Results 131 to 140 of about 15,104 (253)

Impact of Routine Intraoperative Lithotripsy on Surgical Strategy and Outcomes in Laparoscopic Bile Duct Exploration: A Single-Centre Cohort Study. [PDF]

Cureus
Elsamalouty I, Gupta A, Whitmore M, Browning M, Bowling K, Kostalas M, Christopoulos P, Platt T, Sinha S.   +8 more
europepmc   +1 more source

Arsenite methyltransferase 3 is required for mitochondrial function and hepatic lipid metabolism

The FEBS Journal, EarlyView.
AS3MT is a protein that helps the body process arsenic, a naturally occurring toxin found in water and soil. We discovered it also helps cells make and use energy properly. Without AS3MT, cells' mitochondria do not work well, leading to fatty liver and reduced activity. Increasing AS3MT in liver cells restores energy and protects against arsenic damage,
Patrice Delaney, James Griffin, Nouf Khan, Balnur Ibrash, Matthew J. O'Connor, Tomas Venit, Elizabeth Mayela Ambrosio, Spiros A. Pergantis, Elke Ober, Piergiorgio Percipalle, Kirsten C. Sadler   +10 more
wiley   +1 more source

Safety and Outcomes of Laparoscopic Common Bile Duct Exploration in Elderly Patients: A Retrospective Comparative Cohort Study From a High-Volume Specialist Centre. [PDF]

J Hepatobiliary Pancreat Sci
Brazkiewicz M, Latif J, Anderson R, Bhatti I, Awan A.   +4 more
europepmc   +1 more source

Biliary Abnormality on Imaging During Lenvatinib Plus Hepatic Arterial Infusion Chemotherapy With Cisplatin for Hepatocellular Carcinoma: A Pilot Descriptive Study

Hepatology Research, EarlyView.
ABSTRACT Aim To evaluate the frequency, imaging characteristics, associated factors, and clinical significance of biliary abnormalities on imaging in patients receiving lenvatinib (LEN) plus cisplatin hepatic arterial infusion chemotherapy (HAIC) for hepatocellular carcinoma (HCC).
Hirohito Osanai, Kazuto Kozaka, Takashi Matsubara, Norihide Yoneda, Takahiro Ogi, Kenichiro Okumura, Atsushi Takamatsu, Azusa Kitao, Shintaro Yagi, Taro Yamashita, Satoshi Kobayashi   +10 more
wiley   +1 more source

Histological AI‐Assisted Analysis Outperforms Pathologist Assessment in Predicting Disease Outcomes in PSC Patients

Hepatology Research, EarlyView.
Analyzing liver histology with AI assistance demonstrates superior prognostic performance compared to manual scoring in PSC. AI‐measured portal inflammation, fibrosis, biliary epithelium, and blood vessels predicted key clinical endpoints, such as liver transplantation due to end‐stage liver disease, highlighting the importance of liver histology as a ...
Anna M. Salonen, Iiris Nyholm, Linn Tähti, Matilda Sinkko, Darshan Kumar, Martti Färkkilä, Johanna Arola, Mikko P. Pakarinen, Sonja Boyd, Nelli Sjöblom   +9 more
wiley   +1 more source

Spontaneous bilateral subcapsular hepatic hematoma following open cholecystectomy and common bile duct exploration: a rare and life-threatening postoperative complication. [PDF]

BMC Surg
Yasin NA, Jubur AA, Osman AA, Kulle BM, Ahmed AA, Hassan AI.   +5 more
europepmc   +1 more source

Cisterna Chyli Dilation Is a Risk Factor for Liver Nodules and Hepatocellular Carcinoma in Fontan‐Associated Liver Disease: Pathophysiological Role of Lymphatic Dysfunction

Hepatology Research, EarlyView.
ABSTRACT Aim In Fontan‐associated liver disease (FALD), chronic congestion often confounds conventional fibrosis markers, complicating surveillance for hepatocellular carcinoma (HCC). Although lymphatic dysfunction is fundamental to Fontan physiology, its contribution to hepatocarcinogenesis remains unclear.
Koji Imoto, Masatake Tanaka, Takeshi Goya, Yuuki Azuma, Tomonobu Hioki, Yusuke Morita, Keisuke Sakaguchi, Nobuhiro Fujita, Takamori Kakino, Ayako Ishikita, Kenichiro Yamamura, Ichiro Sakamoto, Kousei Ishigami, Kohtaro Abe, Yoshihiro Ogawa   +14 more
wiley   +1 more source

Interrupted suture vs continuous suture for primary closure of the common bile duct after laparoscopic common bile duct exploration in patients with choledocholithiasis. [PDF]

BMC Surg
An T, Wang Y, Deng L, Wang Y, Liu L.
europepmc   +1 more source

Intratumoral IDH1 mutation status in intrahepatic cholangiocarcinoma is homogeneous

Histopathology, EarlyView.
IDH1 mutations are spatially homogeneous in intrahepatic cholangiocarcinoma. Single‐sample molecular testing is sufficient for clinical decision‐making. Introduction IDH1 mutations occur in approximately 10%–20% of intrahepatic cholangiocarcinoma (iCCA) and constitute an established target for molecularly guided therapy.
Sharon Weidmann, Silvana Ebner, Aayushi Srivastava, Armin Wiegering, Stefan Zeuzem, Peter J. Wild, Maximilian N. Kinzler, Melanie C. Winter, Dirk Walter   +8 more
wiley   +1 more source

Magnetic resonance cholangiopancreatography and laparoscopic bile duct exploration should be standard procedures for patients with the ice-breaking sign? [PDF]

World J Gastrointest Surg
Mejuto L, Delgado M, Rabago LR.
europepmc   +1 more source