Results 191 to 200 of about 38,616 (261)

A deceptively benign biliary lesion revealing an ALK‐rearranged intrahepatic cholangiocarcinoma

open access: yes
Histopathology, Volume 89, Issue 1, Page 189-192, July 2026.
Anne‐Cécile Brunac   +5 more
wiley   +1 more source

Integrating antibody–drug conjugates into solid tumor oncology: Current standards and future directions

open access: yesCancer, Volume 132, Issue S1, 1 June 2026.
Abstract Antibody–drug conjugates (ADCs) represent a major advance in precision oncology, combining the selectivity of monoclonal antibodies with the cytotoxic potency of chemotherapy. By enabling targeted intracellular delivery of highly potent payloads, ADCs aim to maximize antitumor activity while minimizing systemic toxicity. This review summarizes
André Mansinho   +3 more
wiley   +1 more source

Metachronous Primary Pancreatic Neuroendocrine Tumor and Adenocarcinoma: A Case Report

open access: yesCancer Reports, Volume 9, Issue 6, June 2026.
ABSTRACT Background Pancreatic ductal adenocarcinoma (PDAC) has a dismal prognosis, with most patients presenting with advanced disease. Surgical resection remains the only potentially curative option, yet recurrence rates are high. Case We present a rare case of metachronous primary pancreatic neuroendocrine tumor (PanNET) and PDAC in a 71‐year‐old ...
Anastasia S. Fatyanova   +7 more
wiley   +1 more source

TGF‐β1‐driven epithelial‒mesenchymal transition mediates the fibrotic process in IgG4‐related disease

open access: yesClinical and Translational Discovery, Volume 6, Issue 3, June 2026.
In IgG4‐related disease, the epithelial‐to‐mesenchymal transition of fibroblasts was predominantly driven by transforming growth factor‐β1 secreted from CD19+ B cells. Reciprocally, fibroblasts facilitated CD19+ B‐cell survival and activation through CXCL14–CXCR4 and CXCL12–CXCR4 signalling axes, thereby promoting B‐cell responses and subsequent ...
In‐Woon Baek   +2 more
wiley   +1 more source

Pancreatic Adenocarcinoma: Diagnosis by Ultrasound‐Guided Fine‐Needle Aspiration—Cyto‐Histological Correlation and Experience at a Multidisciplinary Tertiary Reference Center

open access: yesDiagnostic Cytopathology, Volume 54, Issue 6, Page 403-416, June 2026.
ABSTRACT Background Pancreatic adenocarcinoma (PDAC) is characterized by its poor prognosis. Cytology is essential for diagnostic confirmation and ancillary studies. The endoscopic ultrasound (EUS) set a precedent, facilitating cytological sampling through fine‐needle aspiration (FNA), with a sensitivity of 93% and a specificity of 95%.
Judith González‐López   +10 more
wiley   +1 more source

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