Results 21 to 30 of about 27,992 (288)

Mesenchymal stem cells: A novel treatment option for primary sclerosing cholangitis

open access: yesCell Biology International, Volume 47, Issue 2, Page 467-479, February 2023., 2023
Abstract Primary sclerosing cholangitis (PSC) is a progressive liver disease for which there is no effective therapy. Hepatocytes and cholangiocytes from a PSC patient were cocultured with mesenchymal stem cells (MSCs) to assess in vitro change. A single patient with progressive PSC was treated with 150 million MSCs via direct injection into the common
Amy L. Lightner   +8 more
wiley   +1 more source

The clinicopathological significance and relapse predictive role of tumor microenvironment of intrahepatic cholangiocarcinoma after radical surgery

open access: yesCancer, Volume 129, Issue 3, Page 393-404, 1 February 2023., 2023
Abstract Background This study attempts to detect the expression of FoxP3, CD68, CD8α, and PD‐L1 in the tumor microenvironment (TME) of intrahepatic cholangiocarcinoma (ICC), and analyze the relationship between the corresponding cells and clinicopathological characteristics as well as prognosis of ICC.
Yiling Zheng   +7 more
wiley   +1 more source

Diagnostic pitfalls and the value of fluorescence in situ hybridization as an adjunct to cytologic evaluation of bile duct brushings in patients with primary sclerosing cholangitis

open access: yesDiagnostic Cytopathology, Volume 51, Issue 2, Page 117-122, February 2023., 2023
Abstract Background Primary sclerosing cholangitis (PSC) can present diagnostic difficulties on bile duct brushings as cytologic features mimicking adenocarcinoma may exist. This study evaluates the role of fluorescence in‐situ hybridization (FISH) as an adjunct to cytologic evaluation.
Suzanne M. Selvaggi
wiley   +1 more source

Cold plasma endoscopy applied to biliary ducts: feasibility risk assessment on human-like and porcine models for the treatment of cholangiocarcinoma [PDF]

open access: yesJ. Phys. D. Appl. Phys., Vol. 55, No 45, 2022, 2023
For the past twelve years, cold plasmas have been positioned as a breakthrough technology for treating cancer thanks to their antitumor properties. The innovation of ad hoc plasma sources and personalized protocols appears crucial to treat cancers with a very poor prognosis.
arxiv   +1 more source

Cystadenocarcinoma of the intrahepatic bile duct in a dog

open access: yesJournal of Veterinary Medical Science, 2022
A 14-year-old spayed female Shih-Tzu was referred to the Veterinary Medical Teaching Hospital of Konkuk University for evaluation of an abdominal mass. In diagnostic imaging, two large cystic masses were identified. The affected liver lobes were surgically resected, and the specimens were submitted for histopathological evaluation and ...
KANG, Ji-Hoon   +2 more
openaire   +2 more sources

Histopathology of a benign bile duct lesion in the liver: Morphologic mimicker or precursor of intrahepatic cholangiocarcinoma [PDF]

open access: yesClinical and Molecular Hepatology, 2016
A bile duct lesion originating from intrahepatic bile ducts is generally regarded as an incidental pathologic finding in liver specimens. However, a recent study on the molecular classification of intrahepatic cholangiocarcinoma has focused on the ...
Kyoung-Bun Lee
doaj   +1 more source

TNF receptor–related factor 3 inactivation promotes the development of intrahepatic cholangiocarcinoma through NF‐κB‐inducing kinase–mediated hepatocyte transdifferentiation

open access: yesHepatology, EarlyView., 2022
Abstract Background and Aims Intrahepatic cholangiocarcinoma (ICC) is a deadly but poorly understood disease, and its treatment options are very limited. The aim of this study was to identify the molecular drivers of ICC and search for therapeutic targets.
Yuto Shiode   +16 more
wiley   +1 more source

Bile Duct Segmentation Methods Under 3D Slicer Applied to ERCP: Advantages and Disadvantages [PDF]

open access: yesInternational Journal of Biomedical Engineering and Clinical Science, 2023, 9 (4), pp.66-74, 2023
This article presents an evaluation of biliary tract segmentation methods used for 3D reconstruction, which may be very usefull in various critical interventions, such as endoscopic retrograde cholangiopancreatography (ERCP), using the 3D Slicer software.
arxiv   +1 more source

Phase Ib study of anlotinib combined with TQB2450 in pretreated advanced biliary tract cancer and biomarker analysis

open access: yesHepatology, EarlyView., 2022
Phase 1b study of anlotinib combined with TQB2450 in pretreated advanced biliary tract cancer and biomarker analysis. Abstract Background and Aims We evaluated the efficacy and safety of the antiangiogenic tyrosine kinase inhibitor anlotinib plus TQB2450, a programmed death‐ligand 1 inhibitor in pretreated advanced biliary tract cancers (BTCs ...
Jun Zhou   +13 more
wiley   +1 more source

Fusion Image of Gd-EOB-DTPA MRI and Ultrasound Guiding Microwave Ablation of Hepatocellular Carcinoma Adjacent to Intrahepatic Bile Ducts: A Report of Two Cases [PDF]

open access: yesAdvanced Ultrasound in Diagnosis and Therapy, 2019
Ultrasound (US) has been the most common imaging modality to guide ablation therapy. However, if the tumor is adjacent to intrahepatic bile ducts, only using US as guiding image may not be safe or effective.
Huijuan Peng, MD, Wenzhao Liang, MD, Lei Liu, MD, Jing Jia, MD, Yingqiao Zhu, Dezhi Zhang, MD
doaj   +1 more source

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