Results 161 to 170 of about 700,010 (401)

Associations of body mass index and waist circumference with incidence of overall and of 27 site‐specific cancers: a population‐based retrospective cohort study

open access: yesCancer Communications, EarlyView.
Abstract Background Overweight and obesity are known risk factors for cancer. The aim of this study was to investigate associations of body mass index (BMI) and waist circumference (WC) with incidence of 27 site‐specific cancers stratified by sex and menopausal status accounting for non‐linearity.
Seonghye Kim   +7 more
wiley   +1 more source

Presentation of A Case of Obstructive Jaundice Due to Fasciola hepatica

open access: yesپزشکی بالینی ابن سینا, 2000
Fasciola hepatica is usually a parasite for herbivorouses  bile  ducts. This     parasite can  affect  human via infected water and vegetables . Infection     with this  parasite  can  cause   wide  broad  of  signs  & symptoms. Typical     acute form
Amir Hooshang Mohammad Alizadeh   +2 more
doaj  

Neuroendocrine Carcinoma of the Extrahepatic Bile Ducts: A Case Report. [PDF]

open access: yesAm J Case Rep, 2023
Jevdokimov D   +10 more
europepmc   +1 more source

Ubiquitination in cancer: mechanisms and therapeutic opportunities

open access: yesCancer Communications, EarlyView.
Abstract Ubiquitination, a key post‐translational modification, plays an essential role in tumor biology by regulating fundamental cellular processes, such as metabolism and cell death. Additionally, it interacts with other post‐translational modifications, which are closely linked to tumorigenesis, tumor progression, the tumor microenvironment, and ...
Susi Zhu   +7 more
wiley   +1 more source

Short‐chain acyl post‐translational modifications in cancers: Mechanisms, roles, and therapeutic implications

open access: yesCancer Communications, EarlyView.
Abstract Post‐translational modifications (PTMs) play a pivotal role in epigenetic regulation and are key pathways for modulating protein functionality. PTMs involve the covalent attachment of distinct chemical groups, such as succinyl, crotonyl, and lactyl, at specific protein sites, which alter protein structure, function, stability, and activity ...
Ting Wu   +16 more
wiley   +1 more source

Liver transplantation in biliary atresia with concomitant hepatoma. [PDF]

open access: yes, 1972
Two cases are reported in which the very infrequently reported association was found of liver cell carcinoma and biliary cirrhosis secondary to congenital biliary atresia.
Giles, G   +5 more
core  

Population Pharmacokinetic Modeling of Glycochenodeoxycholic Acid 3‐O‐Sulfate (GCDCA‐S) as Endogenous Biomarker of OATP1B3 and OAT3 Transporters

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Endogenous biomarkers for drug transporters are an emerging tool for the assessment of transporter‐mediated drug–drug interactions (DDI). Glycochenodeoxycholic acid 3‐O‐sulfate (GCDCA‐S) has been proposed as a Tier 2 biomarker of hepatic OATP1B3 and renal OAT3 transporters by the International Transporter Consortium.
Yuki Ujihira   +3 more
wiley   +1 more source

Relieving the bile ducts prior to pancreatoduodenectomy - A retrospective cohort study. [PDF]

open access: yesAnn Med Surg (Lond), 2022
Farooqui W   +5 more
europepmc   +1 more source

Late Pleistocene to Holocene sedimentation in the Great Blue Hole (Lighthouse Reef, Belize): Results from a 30 m long core

open access: yesThe Depositional Record, EarlyView.
A 30 m long sedimentary succession at the bottom of the Belize Blue Hole represents terrestrial cenote (12.5–7.2 ka BP), restricted marine swamp (7.2–5.7 ka BP) and fully marine lagoonal phases (5.7–0 ka BP) on Lighthouse Reef carbonate platform. Post‐glacial and Holocene sea‐level rise largely controlled the sedimentological, faunal and floral changes
Eberhard Gischler   +12 more
wiley   +1 more source

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