Results 221 to 230 of about 861,008 (299)

Retrohepatic Vena Cava Encirclement, as Surrogate of Extensive Liver Manipulation During Caval Sparing Hepatectomy, Is a Risk Factor for Tumor Recurrence After Liver Transplantation for Hepatocellular Carcinoma

open access: yesJournal of Surgical Oncology, EarlyView.
ABSTRACT Introduction In liver transplantation (LT) with a caval sparing (CS) approach, the presence of complete encirclement of inferior vena cava (IVC‐E) by hypertrophic segment 1 increases the technical complexity of hepatectomy. Thus, in LT for hepatocellular carcinoma (HCC), It may be suspected that the resulting greater liver manipulation and ...
Riccardo Pravisani   +9 more
wiley   +1 more source

Recurrent acute pancreatitis caused by a duodenal diverticulum: The diagnostic value of secretin‐enhanced magnetic resonance cholangiopancreatography

open access: yes
Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Dagmar H. Zeef   +5 more
wiley   +1 more source

Organoid Coculture Models for Cancer Research and Immunotherapy

open access: yesMed Research, EarlyView.
This review summarizes organoid coculture platforms, including submerged Matrigel culture, air–liquid interface, microfluidic/organoid‐on‐a‐chip, and 3D bioprinting, for reconstructing the tumor microenvironment to study tumor–stroma/immune crosstalk, evaluate immunotherapies, and enable drug screening.
Zhuo Yang   +9 more
wiley   +1 more source

Free‐Breathing Hepatic Oxygen Extraction Fraction (OEF) Mapping Using Radial GESSE

open access: yesMagnetic Resonance in Medicine, EarlyView.
ABSTRACT Purpose Noninvasive assessment of hepatic oxygenation is relevant for evaluating liver both in acute and long‐term liver pathologies. However, existing methods are limited to single‐slice acquisitions and require breath‐holding. This study aims to develop and evaluate a motion‐robust technique for whole‐liver oxygen extraction fraction (OEF ...
Ke Zhang   +9 more
wiley   +1 more source

DUCK‐Net: automated deep learning segmentation of ductular reactions in murine liver injury captures multicellular niche dynamics from H&E morphology

open access: yesThe Journal of Pathology, EarlyView.
Abstract Ductular reactions (DRs) are dynamic and complex multicellular responses that occur as a result of various hepatic injuries. Precise identification and quantification of the extent of DRs is a cornerstone of pre‐clinical modelling of liver disease, with links to inflammation, fibrosis, regeneration, and disease severity.
Nathalie Feeley   +15 more
wiley   +1 more source

Phytochemicals as Multitarget Therapeutics in Pancreatic Cancer: Mechanisms, Clinical Evidence, and Translational Challenges

open access: yesPhytotherapy Research, EarlyView.
Pancreatic cancer, particularly pancreatic ductal adenocarcinoma, is aggressive and often diagnosed late, making treatment challenging. This review highlights the potential of phytochemicals, such as curcumin and quercetin, as multitarget agents that influence key carcinogenic pathways. These compounds exhibit anticancer effects by inhibiting processes
Md. Rezaul Islam   +7 more
wiley   +1 more source

Protein Corona Engineering of Lipid Nanoparticles Enables Efficient Functional Gene Silencing in the Liver

open access: yesSmall, EarlyView.
By shaping the protein corona, lipid composition directs LNP tropism and enables the preferential delivery of a TIMP1‐targeting siRNA to liver macrophages. In a murine model of primary biliary cholangitis, this strategy promoted macrophage reprogramming and attenuated liver fibrosis.
Naths G. Sukubo   +15 more
wiley   +1 more source

Sporadic Hepatocellular Carcinoma in an Adolescent Harboring a Somatic CDH1 Mutation: A Case Report and Literature Review

open access: yes
The Kaohsiung Journal of Medical Sciences, EarlyView.
Chang‐Wei Su   +2 more
wiley   +1 more source

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