Results 61 to 70 of about 719,832 (406)

Novel Approach to Bile Duct Damage in Primary Biliary Cirrhosis: Participation of Cellular Senescence and Autophagy

International Journal of Hepatology, 2012
Primary biliary cirrhosis (PBC) is characterized by antimitochondrial autoantibodies (AMAs) in patients' sera and histologically by chronic nonsuppurative destructive cholangitis in small bile ducts, eventually followed by extensive bile duct loss and ...
Motoko Sasaki, Yasuni Nakanuma
doaj   +1 more source

A case report of vanishing bile duct syndrome after exposure to pexidartinib (PLX3397) and paclitaxel. [PDF]

, 2019
Pexidartinib (PLX3397) is a small molecule tyrosine kinase and colony-stimulating factor-1 inhibitor with FDA breakthrough therapy designation for tenosynovial giant-cell tumor, and currently under study in several other tumor types, including breast ...
Chien, A Jo, Esserman, Laura J, Hyland, Colby, Piawah, Sorbarikor, Rugo, Hope S, Umetsu, Sarah E   +5 more
core  

A case of distal extrahepatic cholangiocarcinoma with two positive resection margins [PDF]

, 2016
Cholangiocarcinoma is an uncommon primary malignancy of the biliary tract that is challenging to diagnose and treat effectively due to its relatively silent and late clinical presentation.
Andersen, Anderson, Brandi, Brandi, Chung, Dave Harnanan, Ebata, El Rassi, Esposito, Farhat, Geynisman, Han, Hong, Ito, Jarnagin, Khan, Kitagawa, Klöppel, Lazaridis, Murakami, Murakami, Nakeeb, Nuzzo, Parkin, Pitt, Ravi Maharaj, Razumilava, Reddy, Rizvi, Roach, Sasaki, Serafini, Shaib, Soares, Srikanth Umakanthan, Steiner, Wayne A. Warner, Welzel, Wesley Ramcharan, Woo, Yamamoto, Yoshida, Yoshida   +42 more
core   +2 more sources

Postoperative Bile Duct Strictures

Surgical Clinics of North America, 1990
Bile duct strictures are an uncommon but serious complication of primary operations on the gallbladder or biliary tree. Most strictures occur as a result of injury to the bile duct during cholecystectomy. In addition, strictures can occur at the site of previous biliary anastomoses for reconstruction of the biliary tree.
K D, Lillemoe, H A, Pitt, J L, Cameron
openaire   +2 more sources

Novel Vascularized Human Liver Organoids for Modeling Alcohol‐Induced Liver Injury and Developing Hepatoprotective Therapy

Advanced Science, EarlyView.
This study successfully engineered vascularized liver organoids (3HLOs) by co‐culturing human reprogrammed hepatocyte‐like cells (hrHLs) with human umbilical vein endothelial cells (HUVECs) and human umbilical mesenchymal stem cells (HUMSCs). Upon implantation, the 3HLOs established functional vascular anastomosis with the host circulation and ...
Kangdi Yang, Xiayan Chu, Xuerui Wang, Wenkun Zhang, Jinnuo Lu, Chuting Xu, Shoucheng Hu, Guoyu Pan, Chih‐Tsung Yang, Xiaohui Zhang, Shaojin Li, Zhaobin Guo, Hanyang Liu, Guangbo Ge   +13 more
wiley   +1 more source

"HISTOPATHOLOGY OF LIVER IN CATTLE SPONTANEOUSLY INFECTED WITH FASCIOLA HEPATICA AND FASCLOLA GLGANTICA IN IRAN" [PDF]

Iranian Journal of Public Health, 1982
A total of 1500 infected liver with F. hepatica and F. gigantica from slaughtered cattle in different parts of Iran were studied. Grossly the livers were usually irregular in shape, with prominent bile ducts on the visceral surface as grayish-white, firm-
J.Massoud, L.Vedadi
doaj   +2 more sources

METHOD OF EXTRAHEPATIC BILE DUCTS RECONSTRUCTION WITH FORMATION OF AN ACCESS FOR MINIMALLY INVASIVE INTERVENTIONS

Alʹmanah Kliničeskoj Mediciny, 2016
Background: Methods of repair for iatrogenic extrahepatic bile ducts injuries are still under discussion. Aim: To improve surgical outcomes in patients with diseases and iatrogenic injuries of extrahepatic bile ducts.
V. N. Filizhanko, A. I. Lobakov, A. B. Sidorenko   +2 more
doaj   +1 more source

Hypothermic oxygenated machine perfusion prevents arteriolonecrosis of the peribiliary plexus in pig livers donated after circulatory death. [PDF]

PLoS ONE, 2014
BackgroundLivers derived from donation after circulatory death (DCD) are increasingly accepted for transplantation. However, DCD livers suffer additional donor warm ischemia, leading to biliary injury and more biliary complications after transplantation.
Sanna Op den Dries, Michael E Sutton, Negin Karimian, Marieke T de Boer, Janneke Wiersema-Buist, Annette S H Gouw, Henri G D Leuvenink, Ton Lisman, Robert J Porte   +8 more
doaj   +1 more source

Inflammation, Active Fibroplasia, and End-stage Fibrosis in 172 Biliary Atresia Remnants Correlate Poorly With Age at Kasai Portoenterostomy, Visceral Heterotaxy, and Outcome [PDF]

, 2018
Published histologic studies of the hilar plate or entire biliary remnant at the time of Kasai portoenterostomy (KHPE) have not provided deep insight into the pathogenesis of biliary atresia, relation to age at surgery, prognosis or the basis for ...
Arva, Bove, Chen, Davenport, Davenport, De Jong, Feldman, Gautier, Gautier, Gautier, Harpavat, Harpavat, Humphrey, Kolb, Lobeck, Mack, Magalhaes, Mirkin, Nakamura, Petersen, Russo, Sarinet, Schwarz, Shen, Song, Stahlschmidt, Superina, Tan, Tanaka, Volpert, Wong, Yam-Puc, Zheng   +32 more
core   +1 more source

Nuclear Factor I‐B Delays Liver Fibrosis by Inhibiting Chemokine Ligand 5 Transcription

Advanced Science, EarlyView.
This study identifies the transcription factor Nuclear Factor I‐B (NFIB) as a key suppressor of liver fibrosis. NFIB expression declines during hepatic stellate cell activation, and its overexpression reduces fibrosis in mice models. The mechanism involves NFIB directly repressing chemokine C─C motif ligand 5 (CCL5), thereby alleviating oxidative ...
Qianqian Chen, Fajuan Rui, Zhiwen Fan, Hongju Yang, Nan Geng, Chenqi Lu, Wenjing Ni, Yue Huan, Junping Shi, Chao Wu, Shengxia Yin, Wei An, Xia Lu, Qianwen Zhao, Jie Li   +14 more
wiley   +1 more source