Results 51 to 60 of about 645 (124)
Kartierung der zytotoxischen T-Zell-Antwort gegen zwei humane Herpesviren [PDF]
, 2020 Das Humane Cytomegalievirus (HCMV) und das Epstein-Barr-Virus sind weitverbreitet in der Bevölkerung. Beide können schwere Erkrankungen auslösen, die vor allem in immunsupprimierten Infizierten lebensgefährlich werden können.
Lübke, Maren
core +1 more source
, 2019 The Epstein-Barr virus (EBV) BILF1 gene encodes a constitutively active G protein-coupled receptor (GPCR) that downregulates major histocompatibility complex (MHC) class I and induces signaling-dependent tumorigenesis. Different BILF1 homologs display highly conserved extracellular loops (ECLs) including the conserved cysteine residues involved in ...
Wills, Mark +7 more
openaire +2 more sources
The equine herpesvirus 2 E1 open reading frame encodes a functional chemokine receptor [PDF]
, 1999 Several herpesviruses contain open reading frames (ORFs) that encode potential homologs of eucaryotic genes. Equine herpesvirus 2 (EHV-2) is a gammaherpesvirus related to other lymphotropic herpesviruses such as herpesvirus saimiri and Epstein-Barr virus.
Camarda, Grazia +6 more
core +1 more source
The human cytomegalovirus-encoded G protein- coupled receptor UL33 exhibits oncomodulatory properties [PDF]
, 2019 Herpesviruses can rewire cellular signaling in host cells by expressing viral G protein- coupled receptors (GPCRs). These viral receptors exhibit homology to human chemokine receptors, but some display constitutive activity and promiscuous G protein ...
Bebelman, Maarten P. +18 more
core +2 more sources
Additional file 3. BILF1 receptor expression in HEK-293 cells co-transfected with caveolin and dynamin DNMs and in β-arrestin 1/2 KO cells. The figure shows the expression of BILF1 receptors in HEK-293A or βarr1/2 KO cells, which was measured in parallel with internalization using real-time FRET-based method.
Mavri, Maša +6 more
openaire +1 more source
Additional file 2. Principle of the real-time FRET-based method and the intracellular receptor pool calculation. Schematic representation of the principle used to calculate the intracellular receptor pool using RT-FRET-based internalization method.
Mavri, Maša +6 more
openaire +1 more source
Contribution of the KSHV and EBV lytic cycles to tumourigenesis [PDF]
, 2018 Research in the Whitehouse laboratory is supported in parts by funding from Biotechnology and Biological Sciences Research Council (BB/M006557/1, BB/N014405/1), Medical Research Council (MR/R010145/1, 95505168), Worldwide Cancer Research (16-1025 ...
Manners, Oliver +4 more
core +2 more sources
Additional file 5. Immunoprecipitation experiments. Immunoprecipitation experiments, confirming the interaction between BILF1 receptors and AP-2.
Mavri, Maša +6 more
openaire +1 more source
Additional file 1. Informational spectrum (IS) frequency representing common informational characteristics determined using the informational spectrum method (ISM). Common peak corresponding to IS frequency F(0.216) represents physicochemical characteristics based on the structural motif distribution of the BILF1 receptors and corresponds to the ...
Mavri, Maša +6 more
openaire +1 more source
Mechanisms of immune evasion in Epstein-Barr virus infection [PDF]
, 2016 The human herpesvirus Epstein-Barr virus (EBV) is a large DNA virus that infects over 90% of the adult world population. EBV is the causative agent of infectious mononucleosis and EBV infection is associated with various malignancies.
Gram., A.M.
core +1 more source