Results 51 to 60 of about 21,958 (289)
Drug delivery with carbon nanotubes for in vivo cancer treatment [PDF]
Chemically functionalized single-walled carbon nanotubes (SWNTs) have shown promise in tumor targeted accumulation in mice and exhibit biocompatibility, excretion and little toxicity. Here, we demonstrate in-vivo SWNT drug delivery for tumor suppression in mice.
arxiv +1 more source
Latent class mixed modelling for phenotypic stratification of primary biliary cholangitis patients on first line treatment [PDF]
In patients with primary biliary cholangitis (PBC), the serum liver biochemistry measured during treatment with ursodeoxycholic acid (the UDCA response) accurately predicts long-term outcome. In this study we sought to use liver biochemistry, and in particular alkaline phosphatase (ALP), as a surrogate marker of disease activity, for phenotypic ...
arxiv
Biliary atresia is a progressive, idiopathic, obliterative disease of the extrahepatic biliary tree that presents with biliary obstruction in the neonatal period. It is the most common indication for liver transplantation in children.
Tae Yeon Jeon
doaj +1 more source
Cold-atmospheric plasma induces tumor cell death in preclinical in vivo and in vitro models of human cholangiocarcinoma [PDF]
Through the last decade, cold atmospheric plasma (CAP) has emerged as an innovative therapeutic option for cancer treatment. Recently, we have set up a potentially safe atmospheric pressure plasma jet device that displays antitumoral properties in a preclinical model of cholangiocarcinoma (CCA), a rare and very aggressive cancer emerging from the ...
arxiv +1 more source
Biliary atresia with hyaline cartilage at the porta hepatis: a novel finding of undetermined significance: a case report [PDF]
Biliary atresia is an important cause of liver disease and morbidity in infants with unknown etiology. To date, only five cases of biliary atresia with hyaline cartilage at the porta hepatis have been described.
Batra, Vineeta V.+4 more
core +2 more sources
Extrahepatic biliary atresia is an obliterative cholangiopathy that involves all or part of the extrahepatic biliary tree and, in many cases, the intrahepatic bile ducts. In the United States, from 400 to 600 new cases of biliary atresia are encountered annually.
openaire +2 more sources
Novel NIR-II fluorescent probes for biliary atresia imaging
Biliary atresia is a rare infant disease that predisposes patients to liver transplantation and death if not treated in time. However, early diagnosis is challenging because the clinical manifestations and laboratory tests of biliary atresia overlap with
Xiaodong Zeng+9 more
doaj
Background In biliary atresia, the disease process of obliterative cholangiopathy may begin in the perinatal period; however, no chronological evidence exists on how the cholangiopathy progresses to biliary obliteration.
Tsugumichi Koshinaga+4 more
doaj +1 more source
Embryonic Biliary Atresia in a Very-low-birth-weight Premature Infant
Two major forms of biliary atresia, the embryonic and perinatal type, are considered to have different pathogeneses and distinct prognoses. Embryonic biliary atresia is associated with worse prognosis.
Hung-Wen Chen+6 more
doaj +1 more source
Transplantation in children [PDF]
Kidney transplantation in very young children, less than 2 years of age, has usually failed, mainly because of difficulties maintaining these patients on hemodialysis long enough to permit retransplantation after loss of the original graft.
Charles W. Putnam+15 more
core +1 more source