Results 121 to 130 of about 1,208 (169)

A Comprehensive Multiomics Approach Illuminates the Biosynthetic Mechanism of Scoparone in Artemisia capillaris

Plant Biotechnology Journal, EarlyView.
ABSTRACT Artemisia capillaris, a traditional Chinese medicinal plant, has displayed favourable effects in the treatment of jaundice, inflammation of the liver and cholecystitis for thousands of years. However, the biosynthesis of scoparone, the major active component in A. capillaris, remains unclear.
Fuyou Guo, Hong Zhou, Fangfang Yan, Junjie Chen, Qiuyu Zhu, Yu Tan, Yutong Guo, Xiangning Lai, Zongquan Li, Miao Zhang, Yi Ni, Matthana Klakong, Jiamin Yu, Liang Yang, Shili Li, Wei Ding   +15 more
wiley   +1 more source

Diagnosis and surgical management of septic peritonitis in small animals: A review

Veterinary Surgery, EarlyView.
Abstract Background Septic peritonitis (SP) is a complex disease with significant morbidity and mortality. Diagnosis can be challenging, and lack of a timely diagnosis may impact survival. Aim The aim of this review was to synthesize current knowledge on the diagnosis and surgical management of SP in dogs and cats.
Bonnie G. Campbell, Shana K. O'Marra
wiley   +1 more source

Perioperative management of septic peritonitis in small animals: A review

Veterinary Surgery, EarlyView.
Abstract Background Septic peritonitis (SP) is a complex, life‐threatening disease, driven by peritoneal inflammation and microbial contamination, requiring timely and dynamic perioperative management. Aims The aim of this review was to synthesize current knowledge on the perioperative management of SP in dogs and cats.
Shana K. O'Marra, Bonnie G. Campbell
wiley   +1 more source

High Score of ELST‐Blue in Endoscopic Ultrasonography Strain Elastography May Provide a High Risk Group of Early Chronic Pancreatitis with the Reduction of Apolipoprotein A2‐i Index

DEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT Background To evaluate the usefulness of the ELST‐blue score to explore its potential application in identifying high‐risk groups for early chronic pancreatitis (ECP) through reflecting on pancreatic elasticity and the reduction of pancreatic function, and we tried to demonstrate whether the ELST‐blue score was significantly associated with ...
Ken Nakamura, Seiji Futagami, Shuhei Agawa, Sakura Higashida, Tomohide Tanabe, Takeshi Onda, Rie Kawawa, Mayu Habiro, Kumiko Kirita, Songyu Sai, Norio Itokawa, Nobue Ueki, Yoshiyuki Watanabe, Ryo Ohta, Nobuhiko Taniai, Kazufumi Honda, Katsuhiko Iwakiri, Masanori Atsukawa   +17 more
wiley   +1 more source

Adverse Events of Single Balloon Enteroscopy‐assisted Endoscopic Retrograde Cholangiopancreatography in the Elderly: A Propensity Score Matching Analysis

DEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT Background Sedation for conventional endoscopic retrograde cholangiopancreatography (ERCP) has been reported to be safe even for elderly patients. However, the safety of sedation for balloon enteroscopy‐assisted ERCP (BE‐ERCP) has not been well‐studied in the elderly.
Hiroki Nakagawa, Tsuyoshi Takeda, Takeshi Okamoto, Takafumi Mie, Takaaki Furukawa, Takashi Sasaki, Masato Ozaka, Takahisa Matsuda, Yoshinori Igarashi, Naoki Sasahira   +9 more
wiley   +1 more source

A Case of Obstructive Jaundice due to Bile Duct Tumor Thrombus of Hepatocellular Carcinoma Diagnosed by Peroral Cholangioscopy

DEN Open, Volume 6, Issue 1, April 2026.
Abstract While hepatocellular carcinoma (HCC) often invades the portal or hepatic vein to form tumor thrombus, tumor thrombus in the bile duct is rare. In such cases, differentiation from intrahepatic cholangiocarcinoma is difficult, and the tumor often appears as a smooth, yellowish‐white, polypoid mass within the bile duct lumen.
Keisuke Kinoshita, Mizuki Endo, Tomoko Tokumaru, Tomoko Saito, Takuro Uchida, Masao Iwao, Mie Arakawa, Kazuhisa Okamoto, Masaaki Kodama, Kazunari Murakami   +9 more
wiley   +1 more source

Genetic variants underlying precancerous conditions of hepatocellular carcinoma

International Journal of Cancer, Volume 158, Issue 3, Page 488-502, 1 February 2026.
Abstract Hepatocellular carcinoma (HCC) is the most common form of liver cancer, accounting for 80% of cases worldwide. While chronic hepatitis B and C infections remain primary risk factors, emerging evidence highlights the increasing contributions of metabolic dysfunction‐associated steatotic liver disease (MASLD) and alcohol‐associated liver disease
Jonathan Jaime G. Guerrero, Paolo C. Encarnacion, Mark Angelo S. del Rosario, Matthew Aldren S. Ora, Jiayan Zhou, Kin Israel Notarte, Wan‐Chun Li, Ching‐Wen Chang   +7 more
wiley   +1 more source

Association of Individual or Family History of Autoimmune Disease With Future Development of Type 1 Diabetes

Diabetes/Metabolism Research and Reviews, Volume 42, Issue 1, January 2026.
ABSTRACT Timely diagnosis of type 1 diabetes (T1D), especially in high‐risk populations, is crucial for preventing serious health complications. T1D is a chronic progressive autoimmune disease that has presymptomatic stages that can be identified through the detection of islet autoantibodies. Given that T1D is associated with other autoimmune diseases,
Nick Thomas, Bijay Vaidya, Richard David Leslie, Daniel Agardh, Richard Oram, Dana Dabelea, Arunjot Singh, Dimitrios Chantzichristos, Marian Rewers   +8 more
wiley   +1 more source

Type 1 Diabetes and Other Autoimmune Diseases—Epidemiology, Pathophysiology and Screening

Endocrinology, Diabetes &Metabolism, Volume 9, Issue 1, January 2026.
Individuals with type 1 diabetes exhibit significantly increased prevalence of additional autoimmune diseases. Epidemiological, familial and mechanistic evidence indicates frequent polyautoimmunity and shared genetic and environmental drivers. Coexistence complicates clinical management, and autoantibody‐based detection often identifies preclinical ...
George J. Kahaly, Thomas Forst, Monika Kellerer, Stefanie Lanzinger, René D. Rötzer, Matthias Schott, Petra‐Maria Schumm‐Draeger   +6 more
wiley   +1 more source

Metabolic bariatric surgery is associated with reduced adverse hepatic and extrahepatic outcomes, and lower all‐cause mortality, in patients with steatotic liver disease

Diabetes, Obesity and Metabolism, Volume 28, Issue 1, Page 174-185, January 2026.
Abstract Aim Metabolic bariatric surgery (MBS) improves histological endpoints in steatotic liver disease (SLD), but data on longer‐term clinical outcomes in this population are scarce. Here, we assessed the impact of MBS on hepatic and extrahepatic morbidity and mortality in individuals with SLD.
Weronika Stupalkowska, Alexander Henney, Eric G. Sheu, Uazman Alam, Daniel J. Cuthbertson   +4 more
wiley   +1 more source