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Primary biliary cirrhosis [PDF]
Orphanet Journal of Rare Diseases, 2008 Primary biliary cirrhosis (PBC) is a chronic and slowly progressive cholestatic liver disease of autoimmune etiology characterized by injury of the intrahepatic bile ducts that may eventually lead to liver failure.
Heathcote E Jenny, Kumagi Teru
doaj +5 more sources
Annals of Hepatology, 2006 Primary biliary cirrhosis (PBC) is a chronic, cholestat-ic liver disease that is characterized by progressive immune mediated destruction of the intrahepatic bile ducts.
Mary Eugenia Rinella
doaj +6 more sources
Primary biliary cirrhosis: Report [PDF]
Srpski Arhiv za Celokupno Lekarstvo, 2002 Chronic non-suppurative destructive cholangitis, the so-called primary biliary cirrhosis, is characterised by changes, which occur in intrahepatic bile ducts in early stages and in hepatic parenchyma as the disease progresses.
Filipović Branka +3 more
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Association between three autoimmune diseases: vitiligo, primary biliary cirrhosis, and Sjögren's syndrome, [PDF]
Anais Brasileiros de Dermatologia, 2020 Although the association of multiple autoimmune diseases has already been widely described, no reports of the association between vitiligo, primary biliary cirrhosis and Sjogren's syndrome were retrieved in the SciELO and PubMed databases.
Lara Silveira Abdo-Aguiar +1 more
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Primary biliary cirrhosis [PDF]
Medicine, 1997 During the last few years, understanding of the natural history of primary biliary cirrhosis (PBC) has undergone considerable revision, with realisation of the great variability of presentation and progression. The majority of patients are middle-aged women who present with a history of gradual onset of pruritus, increasing skin pigmentation and ...
D E, Jones, M F, Bassendine
core +7 more sources
Autoimmune Hepatitis – Primary Biliary Cirrhosis Overlap Syndrome [PDF]
Journal of Clinical and Diagnostic Research, 2017 Autoimmune Hepatitis (AIH) and Primary Biliary Cirrhosis (PBC) are important immune mediated liver diseases. They are usually differentiated based on clinical, biochemical, serological and histological parameters.
INDIRA BAIRY +2 more
doaj +2 more sources
The diagnosis of primary biliary cirrhosis. [PDF]
Autoimmun Rev, 2014 Primary biliary cirrhosis (PBC) is a chronic liver disease characterized by the immune mediated destruction of small intrahepatic bile duct epithelial cells leading to cholestasis and cirrhosis. The autoimmune basis of PBC is supported by the highly specific anti-mitochondrial antibodies (AMAs) and autoreactive T cells, the former being the basis for ...
Bowlus CL, Gershwin ME.
europepmc +6 more sources
Primary biliary cirrhosis [PDF]
Seminars in Immunopathology, 2009 Primary biliary cirrhosis (PBC) is an immune-mediated chronic cholestatic liver disease with a slowly progressive course. Without treatment, most patients eventually develop fibrosis and cirrhosis of the liver and may need liver transplantation in the late stage of disease.
Hohenester, S. +2 more
openaire +6 more sources
The Indonesian Journal of Gastroenterology, Hepatology and Digestive Endoscopy, 2020 Primary biliary cirrhosis (PBC) is an inflammatory disease or chronic liver inflammation, with slow progressive characteristic and is an unknown cholestatic liver disease and commonly happen in middle-aged women.
Irvan Nugraha +6 more
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Primary biliary cirrhosis [PDF]
Best Practice & Research Clinical Gastroenterology, 2010 Primary biliary cirrhosis (PBC) is an idiopathic chronic autoimmune liver disease that primarily affects women. It is believed that the aetiology for PBC is a combination between environmental triggers in genetically vulnerable persons. The diagnosis for PBC is made when two of the three criteria are fulfilled and they are: (1) biochemical evidence of ...
Douglas L, Nguyen +2 more
openaire +2 more sources