Results 131 to 140 of about 1,208 (169)
International Journal of Cancer, Volume 157, Issue 12, Page 2521-2531, 15 December 2025.What's New? Alcohol's prognostic role in colorectal cancer remains uncertain, partly due to biases in self‐reported intake. This is the first study to evaluate blood DNA methylation‐based alcohol consumption scores as prognostic biomarkers in colorectal cancer.
Tanwei Yuan +8 more
wiley +1 more source
Interaction Between Photoperiod and Sex on Hepatic Lipid Homeostasis in Rats Fed an Obesogenic Diet
The FASEB Journal, Volume 39, Issue 23, 15 December 2025.Male and female Fischer 344 rats were fed a cafeteria (CAF) diet for 11 weeks and exposed to long (L18, 18 h of light per day) or short (L6, 6 h of light per day) photoperiods for 8 weeks. Photoperiod and sex influenced hepatic steatosis, plasmatic and hepatic lipid levels, and hepatic lipid handling, showing sex‐specific metabolic responses to ...
Saioa Gómez‐Roncal +6 more
wiley +1 more source
American Journal of Medical Genetics Part A, Volume 197, Issue 12, December 2025.ABSTRACT Gastrointestinal defects and immunodeficiency syndrome 1 (GIDID1) is a rare autosomal recessive disorder caused by biallelic variants in TTC7A. GIDID1 is characterized by a broad clinical spectrum ranging from very early‐onset inflammatory bowel disease (VEOIBD) to multiple intestinal atresia (MIA) with or without immunological manifestations.
Julia Imhoff +8 more
wiley +1 more source
The Anatomical Record, Volume 308, Issue 12, Page 3197-3229, December 2025.Abstract Plutonium was discovered and first synthesized in the early 1940's. Several isotopes of plutonium are used in nuclear technologies, 238Pu for heat generation and 239Pu for energy production and weapons. Both isotopes emit alpha particles, which pose a significant radiation hazard when incorporated into the body.
Scott C. Miller
wiley +1 more source
Brain and Behavior, Volume 15, Issue 12, December 2025.Bile‐duct ligation (BDL)‐induced memory impairment has a molecular, electrophysiological and histopathological basis and might be regulated by miR‐33‐opioid signaling. The modulation of miR in the brain may be a novel therapeutic approach for relieving neuropathological problems in cholestatic cases, and individuals with cholestasis may benefit from ...
Mohadeseh Rahimi‐vala +4 more
wiley +1 more source
Cancer Medicine, Volume 14, Issue 23, December 2025.ABSTRACT Background Gamma‐glutamyltransferase (GGT) is a membrane‐bound enzyme involved in glutathione metabolism and oxidative stress regulation. Although it is traditionally viewed as a liver function marker, emerging evidence suggests that its aberrant expression is closely associated with tumorigenesis, progression, and therapeutic resistance ...
Fei Wang +11 more
wiley +1 more source
Clinical Case Reports, Volume 13, Issue 12, December 2025.ABSTRACT Multiple autoimmune syndrome involves the concurrent presentation of at least three separate autoimmune conditions in one individual. When patients present with both autoimmune hepatitis (AIH) and primary biliary cholangitis (PBC) simultaneously, it is referred to as AIH‐PBC overlap syndrome.
Tahmina Haque +5 more
wiley +1 more source
Clinical Case Reports, Volume 13, Issue 12, December 2025.ABSTRACT A 17‐year‐old with 80% total body burns developed secondary sclerosing cholangitis (SSC) 3 months post‐injury. This rare liver complication, confirmed by imaging, highlights the need to consider SSC in burn patients presenting with cholestatic liver dysfunction. Early recognition is crucial for timely management and improved outcomes.
Amanda N. Siniora +7 more
wiley +1 more source
Cancer Reports, Volume 8, Issue 12, December 2025.ABSTRACT Background Hepatocellular carcinoma (HCC) is a common primary liver malignancy. Despite advancements in treatment, HCC often has a poor prognosis because of frequent recurrence and metastasis. Hematogenous metastasis to the gastrointestinal tract is uncommon, and metastasis to the small intestine is particularly rare.
Meng‐Kai Hsu +2 more
wiley +1 more source
eFood, Volume 6, Issue 6, December 2025.PTE ameliorates alcohol‐induced gastric injury by regulating oxidative stress and inflammatory responses. Activation of the Keap1/Nrf2/HO‐1 pathway and suppression of NF‐κB pathway may represent the molecular mechanisms by which PTE mediates antioxidative and anti‐inflammatory effects.
Mianhong Xu +5 more
wiley +1 more source