Results 281 to 290 of about 102,708 (355)

Triethylene Tetramine Dihydrochloride Toxicity in Primary Biliary Cirrhosis

, 1980
Owen Epstein, Sheila Sherlock
openalex   +1 more source

Stem Cell Therapy for Inflammatory Diseases: Progress, Challenges, and Future Directions

MedComm, Volume 7, Issue 2, February 2026.
Stem cells offer multifaceted therapeutic approaches for inflammatory diseases, each exhibiting distinct therapeutic properties. Hematopoietic stem cells, primarily through hematopoietic stem cell transplantation (HSCT), can effectively remodel the immune environment, showing particular promise in treating genetically linked cases.
Chen Wu, Zhi‐Ping Jin, Shu‐Qiang Weng, Ji‐Min Zhu, Ling Dong   +4 more
wiley   +1 more source

Bile Acid Binding Resins Improve Glucagon Receptor Agonist‐Mediated Weight Loss in Diet‐Induced Obese Mice

Obesity, Volume 34, Issue 2, Page 428-438, February 2026.
ABSTRACT Objective Glucagon‐receptor (GCGR) agonism reguglates bile acid (BA) metabolism and promotes weight loss in diet‐induced obese (DIO) mice. Thus, we hypothesized that BA signaling contributes to GCGR‐stimulated weight loss. Methods To test this hypothesis, we utilized BA‐binding resins (BARs; colesevelam [Colsv] and cholestyramine [Cstyr]) to ...
Teayoun Kim, Mackenzie J. Pearson, Huixian Hong, Shelly Nason, Khadija Seck, Jessica Antipenko, Natalie Presedo, Richard DiMarchi, William C. Roell, Kirk Habegger   +9 more
wiley   +1 more source

IgM-Positive Tubulointerstitial Nephritis Associated With Asymptomatic Primary Biliary Cirrhosis. [PDF]

Kidney Int Rep, 2018
Mizoguchi S, Katayama K, Murata T, Ishikawa E, Kozuka Y, Honda Y, Oda K, Hirabayashi Y, Ito T, Ito M.   +9 more
europepmc   +1 more source

History of liver and other splanchnic organ transplantation [PDF]

, 1996
Starzl, TE
core  

Development of a Physiologically Based Model of Bilirubin Metabolism in Health and Disease and Its Comparison With Real‐World Data

CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 2, February 2026.
ABSTRACT Bilirubin is a breakdown product of erythrocytes and plays a crucial role in elimination of heme‐containing proteins. After its synthesis in the reticuloendothelial system, unconjugated bilirubin is released into plasma and taken up into the liver.
Ahenk Zeynep Sayin, Lars Kuepfer
wiley   +1 more source

Severe Hepatic Adverse Event Induced by Anti‐HER2 Therapy in Breast Cancer: A Case of Successful Immunotherapy With Baricitinib

ACR Open Rheumatology, Volume 8, Issue 2, February 2026.
Yufei Li, Yifan Wang, Miao Shao, Jing He
wiley   +1 more source

Multi‐Omics Analysis of Human Blood Cells Reveals Unique Features of Age‐Associated Type 2 CD8 Memory T Cells

Aging Cell, Volume 25, Issue 2, February 2026.
Aging drives the accumulation of CXCR3‐ central memory CD8 T cells that exhibit Th2‐like transcriptional and epigenetic programs. These cells display a pathogenic Th2‐skewed profile and are associated with age‐related diseases, including asthma, chronic liver disease, and type 2 diabetes.
Hiroyuki Matsui, Marlene Cervantes, Mir M. Khalid, Alan Tomusiak, Varun Dwaraka, Jorge Landgrave‐Gomez, Prasanna Vadhana Ashok Kumaar, Qingwen Chen, Jessica Lasky‐Su, Jake Stone, Ritesh Tiwari, Ryan Kwok, Shuntaro Ichikawa, Benjamin D. Ambrose, Rebeccah R. Riley, Genesis Vega Hormazabal, Ariel Adkisson‐Floro, Andreea Cristina Alexandru, Ryan Smith, Birgit Schilling, Herbert G. Kasler, Eric Verdin   +21 more
wiley   +1 more source

Prediction of Hepatocellular Carcinoma and Other Liver‐Related Events in Chronic Hepatitis B Patients With Metabolic Dysfunction or Metabolic Dysfunction‐Associated Steatotic Liver Disease

Alimentary Pharmacology &Therapeutics, Volume 63, Issue 3, Page 374-382, February 2026.
This study evaluated the performance of the PAGE‐B score in HCC risk among CHB patients with metabolic dysfunction or MASLD. The PAGE‐B score effectively stratified HCC risk in both MASLD and non‐MASLD patients, especially in those without cirrhosis, where low scores were linked to negligible 5‐year HCC risk. ABSTRACT Introduction Metabolic dysfunction
Lesley A. Patmore, Ivana Carey, Jordan J. Feld, Willem P. Brouwer, Keyur Patel, Maria Buti, Pieter Honkoop, Douwe F. Postma, Hans Blokzijl, Özgur. M. Koc, Eva van Oorschot, Kosh Agarwal, Marc van der Valk, Faydra I. Lieveld, Mai Kilany, Matthijs Kramer, Joep de Bruijne, Mark A. A. Claassen, Bettina E. Hansen, Robert A. de Man, Harry L. A. Janssen, R. Bart Takkenberg, Milan J. Sonneveld   +22 more
wiley   +1 more source

Non‐Response to Obeticholic Acid Is Associated With Heightened Risks of Developing Clinical Events in Primary Biliary Cholangitis

Alimentary Pharmacology &Therapeutics, Volume 63, Issue 4, Page 494-506, February 2026.
In a multi‐centre study of obeticholic acid in primary biliary cholangitis, 45% discontinued the drug over 4 years, with 11% moving to combination therapy (fibrates). Of those continuing, response rates increased from 37% (1 year) to 55% (4 years). Non‐response at 12 months and cirrhosis were independent predictors of liver‐related events.
Nadir Abbas, Rachel Smith, Ellina Lytvyak, Miki Scaravaglio, Neil Halliday, Amal Almahroos, Nadia Eden, Diane Lloyd‐Madden, Sanchit Sharma, James Ferguson, Jessica K. Dyson, Douglas Thorburn, David Jones, Aldo J. Montano‐Loza, Marco Carbone, Pietro Invernizzi, George Mells, Emma L. Culver, Palak J. Trivedi   +18 more
wiley   +1 more source