Results 31 to 40 of about 1,208 (169)

Prevalence of IgA Antibodies to Endomysium and Tissue Transglutaminase in Primary Biliary Cirrhosis

Canadian Journal of Gastroenterology, 2000
The association between celiac disease and primary biliary cirrhosis has been described in several case reports and small screening studies, with varying prevalence rates.
Helen R Gillett, Karen Cauch-Dudek, E Jenny L Healthcote, Hugh J Freeman   +3 more
doaj   +1 more source

AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

, 2022
Hepatology, EarlyView.
Robert J. Fontana, Iris Liou, Adrian Reuben, Ayako Suzuki, M. Isabel Fiel, William Lee, Victor Navarro   +6 more
wiley   +1 more source

Emergence of highly profibrotic and proinflammatory Lrat+Fbln2+ HSC subpopulation in alcoholic hepatitis

Hepatology, EarlyView., 2022
Lrat+ quiescent hepatic stellate cells (qHSC) give rise to Lrat+Fbln2+ activated HSC (aHSC) in alcohol‐associated hepatitis and this subpopulation is highly profibrotic, inflammatory, and immunoregulatory based on their single cell transcriptomic profile. Abstract Background and Aims Relative roles of HSCs and portal fibroblasts in alcoholic hepatitis (
Steven Balog, Reika Fujiwara, Stephanie Q. Pan, Khairat B. El‐Baradie, Hye Yeon Choi, Sonal Sinha, Qihong Yang, Kinji Asahina, Yibu Chen, Meng Li, Matthew Salomon, Stanley W.‐K. Ng, Hidekazu Tsukamoto   +12 more
wiley   +1 more source

Twelve-Year-Old Girl with Primary Biliary Cirrhosis

Case Reports in Pediatrics, 2012
Primary biliary cirrhosis (PBC) is a slowly progressive cholestatic liver disease of autoimmune etiology. The initial presentation of PBC is varies from asymptomatic, abnormal liver biochemical tests to overt cirrhosis.
Ivana Kitic, Aleksandra Boskovic, Ivica Stankovic, Dragan Prokic   +3 more
doaj   +1 more source

Primary biliary cirrhosis

Orphanet Journal of Rare Diseases, 2008
Primary biliary cirrhosis (PBC) is a chronic and slowly progressive cholestatic liver disease of autoimmune etiology characterized by injury of the intrahepatic bile ducts that may eventually lead to liver failure.
Heathcote E Jenny, Kumagi Teru
doaj   +1 more source

Unilateral Trigeminal Sensory Neuropathy with Sjögren’s Syndrome with Liver and Renal Impairment

Neurology International, 2021
Liver and renal involvement is a rare event in Sjögren’s syndrome. Sjögren’s syndrome is characterized by the progressive immune-mediated destruction of epithelial tissues of the salivary and lacrimal glands.
Kana Ozasa, Noboru Noma, Jumi Nakata, Yoshiki Imamura   +3 more
doaj   +1 more source

Primary biliary cirrhosis presenting with ascites and a hepatic hydrothorax: a case report

Journal of Medical Case Reports, 2009
Introduction We report an unusual presentation of primary biliary cirrhosis. Case presentation We present the case of a 66-year-old white British woman who presented to the Accident and Emergency department with ascites and unilateral pleural effusion ...
Wojcikiewicz Thomas George, Gupta Sachin
doaj   +1 more source

Primary Human Tissue Models for Metabolic Dysfunction‐Associated Liver Disease ‐ toward Streamlining Drug Discovery with Patient‐Derived Assays

Advanced Biology, EarlyView.
The review provides a critical up‐to‐date overview of the current landscape of human in vitro models for fatty liver disease, including spheroids, organoids, organ‐on‐a‐chip systems, bioprinted liver constructs and precision‐cut liver slices. Their utility for faithfully modeling different stages of MASLD and MASH are evaluated and their compatibility ...
Sonia Youhanna, Nayere Taebnia, Yingxin Liang, Ningtao Cheng, Yi Wang, Maurice Michel, Volker M. Lauschke   +6 more
wiley   +1 more source

Navigating Transition Metal‐Dependent Cell Death: Mechanisms, Crosstalk, and Future Directions

Advanced Science, EarlyView.
Transition metals trigger distinct regulated cell death pathways beyond traditional apoptosis. This review examines ferroptosis (iron‐catalyzed lipid peroxidation) and cuproptosis (copper‐induced mitochondrial proteotoxicity), while exploring hypothetical “cobaltosis” as a novel pathway.
Qinghang Song, Yuxuan Yang, Lina Yang
wiley   +1 more source

Antibodies to Cardiolipin in Patients with Primary Biliary Cirrhosis

Canadian Journal of Gastroenterology, 1989
Antibodies to cardiolipin have been recognized in up to 65% of patients with systemic lupus erythematosus. It has been claimed that they are significantly associated with intravascular thrombosis and with obstetrical complications.
John Verrier Jones, Dianne P. Mosher, Edith Jones, C. Noel Williams, Dickran Malatjalian, Roland I. Carr, Mervat Mansour   +6 more
doaj   +1 more source