Results 121 to 130 of about 9,207,506 (367)
Advanced Science, EarlyView.This study presents an innovative method to generate high‐quality, objectively annotated cytology datasets without relying on expert involvement. Large‐scale single‐cell DNA sequencing is used as an objective ground truth of cell annotation for generating an accurate, unbiased dataset of exfoliated tumor cells from bronchoalveolar lavage cytology ...
Yichun Zhao +10 more
wiley +1 more source
L0 regularisation for the estimation of piecewise constant hazard rates in survival analysis [PDF]
arXiv, 2016 In a survival analysis context we suggest a new method to estimate the piecewise constant hazard rate model. The method provides an automatic procedure to find the number and location of cut points and to estimate the hazard on each cut interval. Estimation is performed through a penalized likelihood using an adaptive ridge procedure.
arxiv
A COMPARATIVE STUDY OF RENAL AND BILIARY DISEASE IN WHICH CALCULI FIGURE PROMINENTLY. [PDF]
, 1907 A Pond
openalex +1 more source
Engineered Hydrogels for Organoid Models of Human Nonalcoholic Fatty Liver Disease
Advanced Science, EarlyView.Nonalcoholic fatty liver disease (NAFLD) is characterized by lipid accumulation and extracellular matrix stiffening. An in vitro NAFLD model is developed using engineered hydrogels (G′ ≈ 1–6 kPa) and iPSC‐derived hepatic organoids. It is demonstrated that higher stiffness can increase lipid droplet accumulation, fibrosis, and metabolic dysregulation ...
Yueming Liu +11 more
wiley +1 more source
The R Package JMbayes for Fitting Joint Models for Longitudinal and Time-to-Event Data using MCMC [PDF]
arXiv, 2014 Joint models for longitudinal and time-to-event data constitute an attractive modeling framework that has received a lot of interest in the recent years. This paper presents the capabilities of the R package JMbayes for fitting these models under a Bayesian approach using Markon chain Monte Carlo algorithms. JMbayes can fit a wide range of joint models,
arxiv
Engineered Tissue Models to Decode Host–Microbiota Interactions
Advanced Science, EarlyView.Host–Microbiota interactions in the human body. Created in BioRender. Ghezzi, C. (2025) https://BioRender.com/ihivskg. Abstract A mutualistic co‐evolution exists between the host and its associated microbiota in the human body. Bacteria establish ecological niches in various tissues of the body, locally influencing their physiology and functions, but ...
Miryam Adelfio +5 more
wiley +1 more source
A Bioinformatic Approach Validated Utilizing Machine Learning Algorithms to Identify Relevant Biomarkers and Crucial Pathways in Gallbladder Cancer [PDF]
arXivGallbladder cancer (GBC) is the most frequent cause of disease among biliary tract neoplasms. Identifying the molecular mechanisms and biomarkers linked to GBC progression has been a significant challenge in scientific research. Few recent studies have explored the roles of biomarkers in GBC.
arxiv
Plasma Lipoproteins in Liver Disease: I. Immunologically Distinct Low-Density Lipoproteins in Patients with Biliary Obstruction* [PDF]
, 1967 Sam Switzer
openalex +1 more source
Advanced Science, EarlyView.A multifunctional, edible, and hydrogel‐transformable probiotic powder is developed based on the “bacteria‐mediated bacterial eradication” strategy. By leveraging the targeted binding capability of L. reuteri to H. pylori, this approach achieves an integrated therapeutic effect, including bactericidality, anti‐inflammation, gastric mucosal repair, and ...
Yongkang Lai +9 more
wiley +1 more source