Results 1 to 10 of about 608,465 (311)

Organoids: The current status and biomedical applications

open access: yesMedComm, 2023
Organoids are three‐dimensional (3D) miniaturized versions of organs or tissues that are derived from cells with stem potential and can self‐organize and differentiate into 3D cell masses, recapitulating the morphology and functions of their in vivo ...
Siqi Yang   +9 more
doaj   +1 more source

Burden and trends of biliary tract cancer in five Northeast Asian countries, 1990-2021

open access: yesShanghai Jiaotong Daxue xuebao. Yixue ban
Objective·To evaluate the epidemiological characteristics and health inequalities of biliary tract cancer in five Northeast Asian countries (China, Japan, Republic of Korea, Democratic People′s Republic of Korea, and Mongolia) from 1990 to 2021, and to ...
Dong Wenjun   +4 more
doaj   +1 more source

Biliary drainage in malignant biliary obstruction: an umbrella review of randomized controlled trials

open access: yesFrontiers in Oncology, 2023
BackgroundThere are still many controversies about biliary drainage in MBO, and we aimed to summarize and evaluate the evidence associated with biliary drainage.MethodsWe conducted an umbrella review of SRoMAs based on RCTs. Through July 28, 2022, Embase,
Yaoqun Wang   +8 more
doaj   +1 more source

Short-term and Long-term Clinical Outcomes of Combined Caudate Lobectomy for Intrahepatic Cholangiocarcinoma Involving the Hepatic Hilus: A Propensity Score Analysis

open access: yesGut and Liver
Background/Aims: Extended hepatectomy combined with caudate lobe resection has been approved for the radical resection of hilar cholangiocarcinoma. There was a lack of credible research on the clinical value of caudate lobectomy (CL) for intrahepatic ...
Di Zeng   +5 more
doaj   +1 more source

Is conventional functional liver remnant volume higher than 40% still sufficient to prevent post‐hepatectomy liver failure in jaundiced patients with hilar cholangiocarcinoma? A single‐center experience in China

open access: yesCancer Medicine
Objective Our study aims to evaluate the predictive accuracy of functional liver remnant volume (FLRV) in post‐hepatectomy liver failure (PHLF) among surgically‐treated jaundiced patients with hilar cholangiocarcinoma (HCCA).
Tian‐Run Lv   +5 more
doaj   +1 more source

Cordycepin Induces S Phase Arrest and Apoptosis in Human Gallbladder Cancer Cells

open access: yesMolecules, 2014
Gallbladder cancer is the most common malignant tumor of the biliary tract, and this condition has a rather dismal prognosis, with an extremely low five-year survival rate.
Xu-An Wang   +18 more
doaj   +1 more source

Recent Advancements in Known and Emerging Risk Factors of Hepatocellular Carcinoma

open access: yesCancer Medicine
Background Hepatocellular carcinoma (HCC) is the most common primary liver malignancy and a leading cause of cancer‐related deaths worldwide. Despite advancements in antiviral therapies for hepatitis B (HBV) and hepatitis C (HCV), HCC incidence continues
Muhammad Masroor Hussain   +5 more
doaj   +1 more source

Integrating bulk and single cell sequencing data to identify prognostic biomarkers and drug candidates in HBV associated hepatocellular carcinoma

open access: yesScientific Reports
Hepatitis B virus (HBV) infection is a major driver of hepatocellular carcinoma (HCC), yet the mechanisms by which HBV triggers HCC and how it interacts with the immune system remain largely undefined.
Yanjie Zhong   +8 more
doaj   +1 more source

Outcomes after therapeutic SBE-ERCP for choledochojejunal/hepaticojejunal anastomotic stenosis after bile duct injury

open access: yesFrontiers in Surgery
BackgroundCholedochojejunal/hepaticojejunal anastomotic stenosis (CJS/HJS) is significant clinical problem associated with decreased survival postsurgery. Endoscopic retrograde cholangiopancreatography (ERCP) using single-balloon enteroscopy (SBE) is the
Yijun Shu   +38 more
doaj   +1 more source

Individualized Prognostic Insights: CONUT‐GBRS for Survival Prediction in Gallbladder Cancer

open access: yesCancer Medicine
Background The most suitable prognostic prediction system for gallbladder cancer (GBC) is yet to be determined. This study aims to establish a combined score integrating preoperative patients' nutritional and immune status and pathological parameters to ...
Si‐qi Yang   +6 more
doaj   +1 more source

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