Results 41 to 50 of about 608,465 (311)

Non-invasive detection of biliary tract cancer by low-coverage whole genome sequencing from plasma cell-free DNA: A prospective cohort study

open access: yesTranslational Oncology, 2021
Background: The diagnosis of biliary tract cancer (BTC) is challenging in clinical practice. We performed a prospective study to evaluate the value of plasma copy number variation (CNV) assays in diagnosing BTC.
Xiang Wang   +9 more
doaj   +1 more source

Biliary Tract Carcinoma

open access: yesUpsala Journal of Medical Sciences, 1980
A series of 127 patients treated for cancer of the biliary tract during the period 1965-1974 was studied with a follow-up period of at least five years. The mean age was 66 years and the female:male ratio was 3:1. An early diagnosis of biliary tract carcinoma is difficult and the prognosis unfavourable although not hopeless.
V, Skoog, L, Thorén
openaire   +2 more sources

Integrative analyses of bulk and single-cell transcriptomics reveals the infiltration and crosstalk of cancer-associated fibroblasts as a novel predictor for prognosis and microenvironment remodeling in intrahepatic cholangiocarcinoma

open access: yesJournal of Translational Medicine
Background Intrahepatic cholangiocarcinoma (ICC) is a highly malignant neoplasm and characterized by desmoplastic matrix. The heterogeneity and crosstalk of tumor microenvironment remain incompletely understood.
Yan-Jie Zhong   +12 more
doaj   +1 more source

Malignant Biliary Tract Obstruction: Evaluation and Therapy

open access: yes, 2010
Malignant biliary tract obstruction is a common clinical entity. Patients with tumors causing biliary tract obstruction are often asymptomatic until disease is significantly advanced.
Douglas G. Adler, David Chu
core   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Reevaluating Adjuvant Capecitabine for Resected Biliary Tract Cancer [PDF]

open access: yes, 2023
Highlighting concerns about the acceptance of oncologic therapies with no proven benefit, this article compares the interpretation of the clinical trial results of several studies conducted to identify a better therapy for patients with biliary tract ...
Vinay Prasad   +3 more
core   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

open access: yesMolecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla   +4 more
wiley   +1 more source

Printed Integrated Logic Circuits Based on Chitosan‐Gated Organic Transistors for Future Edible Systems

open access: yesAdvanced Functional Materials, EarlyView.
Edible electronics needs integrated logic circuits for computation and control. This work presents a potentially edible printed chitosan‐gated transistor with a design optimized for integration in circuits. Its implementation in integrated logic gates and circuits operating at low voltage (0.7 V) is demonstrated, as well as the compatibility with an ...
Giulia Coco   +8 more
wiley   +1 more source

Clinicopathological parameters of 80 biliary tract cancer patients.

open access: yes, 2016
Clinicopathological parameters of 80 biliary tract cancer patients.
Barbara Uhl (470321)   +11 more
core   +1 more source

Pathologies of Precursor Lesions of Biliary Tract Carcinoma

open access: yes, 2022
Carcinomas and precursor lesions of the biliary tract belong to a spectrum of pancreatobiliary neoplasms that share common histology and cell lineages.
Takashi Sugino   +9 more
core   +1 more source

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