Results 41 to 50 of about 100,198 (214)

Integrative analyses of bulk and single-cell transcriptomics reveals the infiltration and crosstalk of cancer-associated fibroblasts as a novel predictor for prognosis and microenvironment remodeling in intrahepatic cholangiocarcinoma

Journal of Translational Medicine
Background Intrahepatic cholangiocarcinoma (ICC) is a highly malignant neoplasm and characterized by desmoplastic matrix. The heterogeneity and crosstalk of tumor microenvironment remain incompletely understood.
Yan-Jie Zhong, Xi-Mei Luo, Fei Liu, Zhi-Qiang He, Si-Qi Yang, Wen-Jie Ma, Jun-Ke Wang, Yu-Shi Dai, Rui-Qi Zou, Ya-Fei Hu, Tian-Run Lv, Fu-Yu Li, Hai-Jie Hu   +12 more
doaj   +1 more source

Bile acid analysis in biliary tract cancer [PDF]

, 2006
The etiology of biliary tract cancer is obscure, but there are evidences that bile acid plays a role in carcinogenesis. To find the association between biliary tract cancer and bile acid, this study compared the bile acid concentration and composition ...
고준상, 박정엽, 방승민, 정재복, 박병규, 송시영   +5 more
core   +1 more source

Surgical anatomy of the biliary tract [PDF]

, 2008
An intimate knowledge of the morphological, functional, and real anatomy is a prerequisite for obtaining optimal results in the complex surgery of extra and intrahepatic cholangiocarcinoma.
Castaing, Denis
core   +1 more source

Immunotherapy in Advanced Biliary Tract Cancers [PDF]

, 2021
Biliary tract cancers are rare tumors with a poor prognosis. Two-thirds of these primary liver malignancies are diagnosed at advanced stages where therapeutic options are limited.
Michel Ducreux, Alice Boilève, Antoine Hollebecque, Marc Hilmi, Cristina Smolenschi, David Malka   +5 more
core   +1 more source

Short-term and Long-term Clinical Outcomes of Combined Caudate Lobectomy for Intrahepatic Cholangiocarcinoma Involving the Hepatic Hilus: A Propensity Score Analysis

Gut and Liver
Background/Aims: Extended hepatectomy combined with caudate lobe resection has been approved for the radical resection of hilar cholangiocarcinoma. There was a lack of credible research on the clinical value of caudate lobectomy (CL) for intrahepatic ...
Di Zeng, Yaoqun Wang, Ningyuan Wen, Bei Li, Nansheng Cheng, Jiong Lu   +5 more
doaj   +1 more source

Vascular factors, angiogenesis and biliary tract disease [PDF]

, 2010
Purpose of review Recent studies have brought to light that angiogenesis and the expression of pro-angiogenic factors such as vascular endothelial growth factors (VEGFs) participate in the pathogenesis of biliary tract diseases.
Gianfranco Alpini, Shannon S. Glaser, GAUDIO, EUGENIO   +2 more
core   +1 more source

In-hospital mortality after resection of biliary tract cancer in the United States [PDF]

, 2010
ObjectiveTo assess perioperative mortality following resection of biliary tract cancer within the U.S.BackgroundResection remains the only curative treatment for biliary tract cancer. However, current data on operative mortality after surgical resections
McPhee, James T., Tseng, Jennifer F., Sing Chau Ng, Shah, Shimul A., James T. McPhee, Shimul A. Shah, Carroll, James E. Jr., Carroll Jr, James E., Hurwitz, Zachary M., Zachary M. Hurwitz, James E. Carroll Jr, Jessica P. Simons, Simons, Jessica P., Ng, Sing Chau, Al-Refaie, Waddah B., Jennifer F. Tseng, Waddah B. Al-Refaie   +16 more
core   +1 more source

Biliary tract cancers: current knowledge, clinical candidates and future challenges [PDF]

, 2019
Noor-ul-Ain Tariq,1,2 Mairéad G McNamara,1,2 Juan W Valle1,2 1Faculty of Biomedicine and Health Sciences, Division of Cancer Sciences, University of Manchester, Manchester M13 9NT, UK; 2Department of Medical Oncology, The Christie NHS Foundation ...
Tariq N, McNamara MG, Valle JW
core  

Microbiome and Biliary Tract Cancer [PDF]

Biliary tract cancers encompass a group of malignancies that affect the bile ducts and gallbladder and are associated with a poor prognosis, often due to late diagnosis and limited treatment options.
Jin-Seok Park
core   +1 more source

Adaptive regulation of the ileal apical sodium dependent bile acid transporter (ASBT) in patients with obstructive cholestasis. [PDF]

, 2005
Background/Aims The apical sodium dependent bile acid transporter ASBT (SLC10A2) contributes substantially to the enterohepatic circulation of bile acids by their reabsorption from the intestine. In the rat, its adaptive regulation was observed in the
Gutmann, H., Drewe, J., Beglinger, C., Degen, L., Terracciano, L., Zimmermann, Christian, Gutmann, Heike, Hruz, P., Zimmermann, C., Beuers, Ulrich, Drewe, Jürgen, Terracciano, Luigi, Degen, Lukas, Beuers, U., Hruz, Petz, Beglinger, Christoph   +15 more
core   +1 more source