Results 31 to 40 of about 100,198 (214)

Pathologies of Precursor Lesions of Biliary Tract Carcinoma [PDF]

open access: yes, 2022
Carcinomas and precursor lesions of the biliary tract belong to a spectrum of pancreatobiliary neoplasms that share common histology and cell lineages.
Takashi Sugino   +9 more
core   +1 more source

KRAS G12D mutation eliminates reactive oxygen species through the Nrf2/CSE/H 2S axis and contributes to pancreatic cancer growth

open access: yesActa Biochimica et Biophysica Sinica, 2022
In pancreatic cancer, KRAS G12D can trigger pancreatic cancer initiation and development. Rapid tumor growth is often accompanied by excess intracellular reactive oxygen species (ROS) production, which is unfavorable to tumor.
Fan Kun   +9 more
doaj   +1 more source

Non-invasive detection of biliary tract cancer by low-coverage whole genome sequencing from plasma cell-free DNA: A prospective cohort study

open access: yesTranslational Oncology, 2021
Background: The diagnosis of biliary tract cancer (BTC) is challenging in clinical practice. We performed a prospective study to evaluate the value of plasma copy number variation (CNV) assays in diagnosing BTC.
Xiang Wang   +9 more
doaj   +1 more source

Radiological findings and surgical outcomes of pulmonary metastases originating from biliary tract carcinoma [PDF]

open access: yes, 2019
Purpose: Metastasis to the lungs arising from biliary tract carcinoma (BTC) is extremely rare, and the patient characteristics and prognosis are not well known.
Nakamura, Shota   +4 more
core   +1 more source

Fasting-induced RNF152 resensitizes gallbladder cancer cells to gemcitabine by inhibiting mTORC1-mediated glycolysis

open access: yesiScience
Summary: Abnormal mTORC1 activation by the lysosomal Ragulator complex has been implicated in cancer and glycolytic metabolism associated with drug resistance. Fasting upregulates RNF152 and mediates the metabolic status of cells.
Ying Tao   +13 more
doaj   +1 more source

Additional BCAA-enriched nutrient mixture improves the nutritional condition in cirrhotic patients with hypoalbuminemia despite treatment with regular BCAA granules: A pilot study

open access: yesThe Turkish Journal of Gastroenterology, 2015
Background/Aims: To elucidate the effect of adding branched-chain amino acid (BCAA)-enriched nutrient mixtures in cirrhotic patients with hypoalbuminemia despite the use of BCAA granules. Materials and Methods: A BCAA-enriched nutrient mixture containing
Aiko Fukui   +11 more
doaj   +1 more source

Endoscopic Treatment of Minor Biliary Tract Injuries Due to Cholecystectomy: Single Center Experience [PDF]

open access: yes
Objective: Minor biliary injuries make up about 50% of cholecystectomy-related biliary injuries. In this study, an evaluation of the technical features, technical efficacy, and clinical outcomes of endoscopic treatment for patients with minor biliary ...
Kerem Kenarlı   +2 more
core   +1 more source

Organoids: The current status and biomedical applications

open access: yesMedComm, 2023
Organoids are three‐dimensional (3D) miniaturized versions of organs or tissues that are derived from cells with stem potential and can self‐organize and differentiate into 3D cell masses, recapitulating the morphology and functions of their in vivo ...
Siqi Yang   +9 more
doaj   +1 more source

Biliary drainage in malignant biliary obstruction: an umbrella review of randomized controlled trials

open access: yesFrontiers in Oncology, 2023
BackgroundThere are still many controversies about biliary drainage in MBO, and we aimed to summarize and evaluate the evidence associated with biliary drainage.MethodsWe conducted an umbrella review of SRoMAs based on RCTs. Through July 28, 2022, Embase,
Yaoqun Wang   +8 more
doaj   +1 more source

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