Results 41 to 50 of about 9,590,921 (389)
World Journal of Gastroenterology, 2012 Cholangiopathies are a group of diseases primarily or secondarily affecting bile duct cells, and result in cholangiocyte proliferation, regression, and/or transformation. Their etiopathogenesis may be associated with a broad variety of causes of different nature, which includes genetic, neoplastic, immune-associated, infectious, vascular, and drug ...
Patricia, Munoz-Garrido +6 more
openaire +2 more sources
Cordycepin Induces S Phase Arrest and Apoptosis in Human Gallbladder Cancer Cells
Molecules, 2014 Gallbladder cancer is the most common malignant tumor of the biliary tract, and this condition has a rather dismal prognosis, with an extremely low five-year survival rate.
Xu-An Wang +18 more
doaj +1 more source
TRPM8 contributes to liver regeneration via mitochondrial energy metabolism mediated by PGC1α
Cell Death and Disease, 2022 Impairment of liver regeneration leads to severe morbidity in acute and chronic severe liver disease. Transient receptor potential melastain 8 (TRPM8) is involved in a variety of processes, including temperature sensing, ion homeostasis, and cell ...
Xiaohua Lei +20 more
doaj +1 more source
Neoplasia: An International Journal for Oncology Research, 2023 Background: Most patients with resected bile tract cancers (BTCs) survive for less than 5 years; however, some achieve better prognosis. The tumor microbiome can improve survival by regulating the tumor immune microenvironment. However, whether the tumor
Wen-Jie Ma +7 more
doaj +1 more source
The microbiota of the bilio-pancreatic system: A cohort, STROBE-compliant study [PDF]
, 2019 Background: The gut microbiota play an essential role in protecting the host against pathogenic microorganisms by modulating immunity and regulating metabolic processes.
Agrusa A. +8 more
core +1 more source
Canadian Journal of Gastroenterology and Hepatology, 2021 Purpose. The aim of the study was to investigate the effect of hyperthermic intraperitoneal perfusion chemotherapy (HIPEC) combined with radical surgery and capecitabine on stage III gallbladder cancer. Method.
Sulai Liu +8 more
doaj +1 more source
A phase II study of capecitabine and oxalplatin combination chemotherapy in patients with inoperable adenocarcinoma of the gall bladder or biliary tract [PDF]
, 2016 Background: Advanced biliary tract carcinomas are associated with a poor prognosis, and palliative chemotherapy has only modest benefit. This multi-centre phase II study was conducted to determine the efficacy of capecitabine in combination with ...
E. Soulis +10 more
core +1 more source
The Role of Cholangioscopy in Biliary Diseases
Diagnostics, 2023 Endoscopy plays a central role in diagnostic and therapeutic approaches to biliary disease in both benign and malignant conditions. A cholangioscope is an endoscopic instrument that allows for the direct exploration of the biliary tree.
Aurelio Mauro +7 more
semanticscholar +1 more source
iScienceSummary: Abnormal mTORC1 activation by the lysosomal Ragulator complex has been implicated in cancer and glycolytic metabolism associated with drug resistance. Fasting upregulates RNF152 and mediates the metabolic status of cells.
Ying Tao +13 more
doaj +1 more source
Cancer Medicine, 2023 Background Hepatocellular carcinoma (HCC) has a poor prognosis and new effective treatments are needed. SLC12A5 plays important roles in multiple complex pathological states and is overexpressed in a variety of malignancies.
Qing Tong +6 more
doaj +1 more source