Results 41 to 50 of about 9,207,506 (367)
Objective The etiopathogenesis and risk for development of biliary neoplasia in primary sclerosing cholangitis (PSC) are largely unknown. Microbes or their metabolites have been suggested to play a role.
P. Pereira+7 more
semanticscholar +1 more source
Bile dynamics within the biliary tract and microfluidic-based bile component detection: A review [PDF]
Bilestones are solid masses found in the gallbladder or biliary tract, which block the normal bile flow and eventually result in severe life-threatening complications. Studies have shown that bilestone formation may be related to bile flow dynamics and the concentration level of bile components.
arxiv
Drug delivery with carbon nanotubes for in vivo cancer treatment [PDF]
Chemically functionalized single-walled carbon nanotubes (SWNTs) have shown promise in tumor targeted accumulation in mice and exhibit biocompatibility, excretion and little toxicity. Here, we demonstrate in-vivo SWNT drug delivery for tumor suppression in mice.
arxiv +1 more source
Immunoglobulin G4 (IgG4)‐related disease (IgG4‐RD) of the biliary tree and pancreas is difficult to distinguish from sclerosing cholangitis and biliary/pancreatic malignancies (CA).
M. Doorenspleet+12 more
semanticscholar +1 more source
Accumulating evidence demonstrates that the integration of preoperative geriatric assessment and prehabilitation for frail patients into clinical practice may improve perioperative and long‐term outcomes in patients with gastrointestinal cancer. We proposed an example for the integration of older patients‐specific care into treatment strategies for ...
Kosuke Mima+4 more
wiley +1 more source
The anticancer activity of bile acids in drug discovery and development
Bile acids (BAs) constitute essential components of cholesterol metabolites that are synthesized in the liver, stored in the gallbladder, and excreted into the intestine through the biliary system.
Weijian Li+28 more
doaj +1 more source
Triptolide Induces S Phase Arrest and Apoptosis in Gallbladder Cancer Cells
Gallbladder carcinoma is the most common malignancy of the biliary tract, with a very low 5-year survival rate and extremely poor prognosis. Thus, new effective treatments and drugs are urgently needed for the treatment of this malignancy. In this study,
Yun-Ping Hu+11 more
doaj +1 more source
Cell‐free and extracellular vesicle microRNAs with clinical utility for solid tumors
Cell‐free microRNAs (cfmiRs) are small‐RNA circulating molecules detectable in almost all body biofluids. Innovative technologies have improved the application of cfmiRs to oncology, with a focus on clinical needs for different solid tumors, but with emphasis on diagnosis, prognosis, cancer recurrence, as well as treatment monitoring.
Yoshinori Hayashi+6 more
wiley +1 more source
High tumor budding is a new candidate for an additional determinant of the T category in staging ICC. An LCSGJ staging system containing an additional evaluation of tumor budding may lead to improved staging accuracy. Abstract Purpose This retrospective study evaluated our hypothesis that high tumor budding (≥10 buds) may help determine the appropriate
Hisashi Kosaka+9 more
wiley +1 more source
Long non-coding RNAs (lncRNAs) have been identified as critical contributors in tumor progression for many types of cancer. However, their functions in gallbladder cancer (GBC) have not been systematically clarified.
Bohao Zheng+12 more
doaj