Results 51 to 60 of about 9,590,921 (389)

Successful conversion surgery for locally advanced gallbladder cancer after gemcitabine and nab-paclitaxel chemotherapy

Frontiers in Oncology, 2022
ObjectiveGallbladder cancer (GBC) is highly malignant and is often diagnosed at the advanced stage. Lack of opportunity to surgery results in an unsatisfactory outcome.
Ziyi Yang, Ziyi Yang, Ziyou Wu, Ziyou Wu, Yichen Xiong, Yichen Xiong, Shilei Liu, Shilei Liu, Chen Cai, Chen Cai, Ziyu Shao, Ziyu Shao, Yidi Zhu, Yidi Zhu, Xiaoling Song, Xiaoling Song, Wei Shen, Xuefeng Wang, Xuefeng Wang, Xiangsong Wu, Xiangsong Wu, Wei Gong, Wei Gong   +22 more
doaj   +1 more source

Does the size of the neuroendocrine-carcinoma component determine the prognosis of gallbladder cancer?

Frontiers in Endocrinology
BackgroundGallbladder mixed neuroendocrine-non-neuroendocrine neoplasm generally consists of a gallbladder neuroendocrine tumor and a non-neuroendocrine component.
Ya-Fei Hu, Ya-Fei Hu, Jun-Ke Wang, Jun-Ke Wang, Wen-Jie Ma, Wen-Jie Ma, Hai-Jie Hu, Hai-Jie Hu, Han-Fei Gu, Han-Fei Gu, Fei Liu, Fei Liu, Tian-Run Lv, Tian-Run Lv, Si-Qi Yang, Si-Qi Yang, Yu-Shi Dai, Yu-Shi Dai, Rui-Qi Zou, Rui-Qi Zou, Yan-Wen Jin, Yan-Wen Jin, Fu-Yu Li, Fu-Yu Li   +23 more
doaj   +1 more source

Biliary secretion and excretion in health and disease: Current concepts

Annals of Hepatology, 2007
Biliary secretion in health and disease is reviewed. The powerful techniques of molecular biology have enabled cloning of the transporters involved in biliary secretion and the enterohepatic circulation of bile acids.
Alan F Hofmann
doaj   +1 more source

The anticancer activity of bile acids in drug discovery and development

Frontiers in Pharmacology
Bile acids (BAs) constitute essential components of cholesterol metabolites that are synthesized in the liver, stored in the gallbladder, and excreted into the intestine through the biliary system.
Weijian Li, Weijian Li, Weijian Li, Weijian Li, Lu Zou, Lu Zou, Lu Zou, Lu Zou, Shuai Huang, Huijie Miao, Huijie Miao, Huijie Miao, Huijie Miao, Ke Liu, Ke Liu, Ke Liu, Ke Liu, Yajun Geng, Yajun Geng, Yajun Geng, Yajun Geng, Yingbin Liu, Yingbin Liu, Yingbin Liu, Yingbin Liu, Wenguang Wu, Wenguang Wu, Wenguang Wu, Wenguang Wu   +28 more
doaj   +1 more source

Transport of apolipoproteins A-I and A-II by human thoracic duct lymph [PDF]

, 1981
The daily transport of human plasma apolipoproteins A-I and A-II, triglyceride, and total cholesterol from the thoracic duct lymph into plasma was measured in 2 subjects before and 3 subjects after renal transplantation. Lymph triglyceride transport was ~
Anderson, DW, Brewer, HB, Bronzert, TJ, Forte, T, Lindgren, FT, Niblack, GD, Schaefer, EJ, Starzl, TE, Zech, LA   +8 more
core   +1 more source

Effects of vedolizumab, adalimumab and infliximab on biliary inflammation in individuals with primary sclerosing cholangitis and inflammatory bowel disease

Alimentary Pharmacology and Therapeutics, 2018
Primary sclerosing cholangitis (PSC) is a chronic, progressive cholestatic biliary disease associated with inflammatory bowel disease (IBD) with no known cure.
C. Tse, E. Loftus, L. Raffals, A. Gossard, A. Lightner   +4 more
semanticscholar   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

Triptolide Induces S Phase Arrest and Apoptosis in Gallbladder Cancer Cells

Molecules, 2014
Gallbladder carcinoma is the most common malignancy of the biliary tract, with a very low 5-year survival rate and extremely poor prognosis. Thus, new effective treatments and drugs are urgently needed for the treatment of this malignancy. In this study,
Yun-Ping Hu, Zhu-Jun Tan, Xiang-Song Wu, Tian-Yu Liu, Lin Jiang, Run-Fa Bao, Yi-Jun Shu, Mao-Lan Li, Hao Weng, Qian Ding, Feng Tao, Ying-Bin Liu   +11 more
doaj   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Impact of combination antiretroviral therapy in the NOD.c3c4 mouse model of autoimmune biliary disease

Liver international (Print), 2014
The NOD.c3c4 mouse model develops autoimmune biliary disease characterized by spontaneous granulomatous cholangitis, antimitochondrial antibodies and liver failure.
D. Sharon, Min Chen, Guangzhi Zhang, S. Girgis, B. Sis, Don Graham, C. McDougall, S. Wasilenko, A. Montaño-Loza, A. Mason   +9 more
semanticscholar   +1 more source