Results 61 to 70 of about 9,207,506 (367)

Prognostic factors in conversion surgery following nab‐paclitaxel with gemcitabine and subsequent chemoradiotherapy for unresectable locally advanced pancreatic cancer: Results of a dual‐center study

open access: yesAnnals of Gastroenterological Surgery, Volume 7, Issue 1, Page 157-166, January 2023., 2023
For radical surgery after induction gemcitabine along with nab‐paclitaxel and subsequent chemoradiotherapy for unresectable locally advanced pancreatic ductal adenocarcinoma, CA19‐9 normalization and maintenance of good nutritional status during treatment until surgery were important for prolonged prognosis.
Takamichi Igarashi   +9 more
wiley   +1 more source

Outbreak of Hantavirus Pulmonary Syndrome, Los Santos, Panama, 1999–2000

open access: yesEmerging Infectious Diseases, 2004
An outbreak of hantavirus pulmonary syndrome occurred in the province of Los Santos, Panama, in late 1999 and early 2000. Eleven cases were identified; 9 were confirmed by serology. Three cases were fatal; however, no confirmed case-patient died.
Vicente Bayard   +21 more
doaj   +1 more source

tRF-3013b inhibits gallbladder cancer proliferation by targeting TPRG1L

open access: yesCellular & Molecular Biology Letters, 2022
Background tRNA-derived fragments (tRFs) are newly discovered noncoding RNAs and regulate tumor progression via diverse molecular mechanisms. However, the expression and biofunction of tRFs in gallbladder cancer (GBC) have not been reported yet.
Lu Zou   +12 more
doaj   +1 more source

Liver and Biliary Disease in Infancy

open access: yesMedicine, 2002
Liver disease in infancy is a relatively rare but serious cause of morbidity and mortality. Since jaundice is a common finding in the neonatal period, the immediate priority is to differentiate between unconjugated hyperbilirubinaemia, which is generally a benign developmental phenomenon, and conjugated hyperbilirubinaemia (conjugated fraction >20 ...
Francavilla, R, Mieli-Vergani, G
openaire   +4 more sources

Intraoral Drug Delivery: Bridging the Gap Between Academic Research and Industrial Innovations

open access: yesAdvanced Functional Materials, EarlyView.
Intraoral drug delivery offers a promising route for systemic and localized therapies, yet challenges such as enzymatic degradation, limited permeability, and microbial interactions hinder efficacy. This figure highlights innovative strategies—mucoadhesive materials, enzyme inhibitors, and permeation enhancers—to overcome these barriers.
Soheil Haddadzadegan   +4 more
wiley   +1 more source

Do postoperative infectious complications really affect long‐term survival in colorectal cancer surgery? A multicenter retrospective cohort study

open access: yesAnnals of Gastroenterological Surgery, Volume 7, Issue 1, Page 110-120, January 2023., 2023
This multicenter retrospective cohort study suggested that postoperative infection (PI) after curative colorectal surgery (CRC) is associated with impaired oncological outcomes. Strategies to prevent PI and implement appropriate postoperative treatment may improve the quality of care and oncological outcomes in patients undergoing curative CRC surgery.
Akihisa Matsuda   +18 more
wiley   +1 more source

Protective effect of oil from Cornus wilsoniana fruits against carbon tetrachloride-induced hepatic fibrosis in mice

open access: yesFood & Nutrition Research, 2020
Background: Cornus wilsoniana Wanger is a widely distributed woody oil plant in south China; oil extracted from its fruits has been the main source of edible oil for local residents for hundreds of years.
Qiang Liu   +14 more
doaj   +1 more source

Case report: A de novo ERBB3 mutation develops in a gallbladder cancer patient carrying BRCA1 mutation after effective treatment with olaparib

open access: yesFrontiers in Oncology, 2023
BackgroundGallbladder cancer (GBC) is highly lethal and resistant to most chemotherapeutic drugs. GBC was reported to carry multiple genetic mutations such as TP53, K-RAS, and ERBB2/3.
Jing-Xiao Yang   +25 more
doaj   +1 more source

“Therapies Through Gut:” Targeted Drug Delivery for Non‐Gastrointestinal Diseases by Oral Administration

open access: yesAdvanced Healthcare Materials, EarlyView.
Schematic illustration of the mechanism of targeted delivery of nanoparticles including 1) paracellular, 2) endolysosomal escape, 3) receptor mediated endocytosis, and 4) M cell mediated transport for non‐GI diseases by oral administration such as atherosclerosis, cancer, diabetes, and brain diseases. Abstract Oral drug delivery is a promising approach
Subarna Ray   +2 more
wiley   +1 more source

A Consensus Meeting on Expert Recommendations on Operating Specifications for Laparoscopic Radical Resection of Hilar Cholangiocarcinoma

open access: yesFrontiers in Surgery, 2021
Background: With advances in techniques and technologies, laparoscopic radical resection of hilar cholangiocarcinoma (HCCA) has gradually been carried out in major medical centers in China.
Yongfu Xiong   +8 more
doaj   +1 more source

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