Results 31 to 40 of about 141,658 (207)

Characterisation of the immune-related transcriptome in resected biliary tract cancers [PDF]

, 2017
Although biliary tract cancers (BTCs) are known to have an inflammatory component, a detailed characterisation of immune-related transcripts has never been performed.
Braconi, Chiara, Carotenuto, Pietro, Cascione, Luciano, Cillo, Umberto, Fassan, Matteo, Ghidini, Michele, Hahne, Jens C., Lampis, Andrea, Mescoli, Claudia, Previdi, Maria Chiara, Raj, Maya, Rimassa, Lorenza, Roncalli, Massimo, Rugge, Massimo, Said-Huntingford, Ian, Santoro, Armando, Torzilli, Guido, Trevisani, Francesco, Valeri, Nicola, Zerbi, Alessandro   +19 more
core   +3 more sources

Fasting-induced RNF152 resensitizes gallbladder cancer cells to gemcitabine by inhibiting mTORC1-mediated glycolysis

iScience
Summary: Abnormal mTORC1 activation by the lysosomal Ragulator complex has been implicated in cancer and glycolytic metabolism associated with drug resistance. Fasting upregulates RNF152 and mediates the metabolic status of cells.
Ying Tao, Zijun Gong, Sheng Shen, Yaqi Ding, Rui Zan, Bohao Zheng, Wentao Sun, Chaolin Ma, Mengxuan Shu, Xiao Lu, Han Liu, Xiaoling Ni, Houbao Liu, Tao Suo   +13 more
doaj   +1 more source

Organoids: The current status and biomedical applications

MedComm, 2023
Organoids are three‐dimensional (3D) miniaturized versions of organs or tissues that are derived from cells with stem potential and can self‐organize and differentiate into 3D cell masses, recapitulating the morphology and functions of their in vivo ...
Siqi Yang, Haijie Hu, Hengchung Kung, Ruiqi Zou, Yushi Dai, Yafei Hu, Tiantian Wang, Tianrun Lv, Jun Yu, Fuyu Li   +9 more
doaj   +1 more source

Adult liver transplantation: An analysis of the early causes of death in 40 consecutive cases [PDF]

, 1986
One hundred twenty‐nine adult patients who received an orthotopic liver transplantation and survived at least 24 hr after surgery were evaluated. During the period of follow‐up, 48 of the 129 patients (37%) died.
Calne, Demetris, Dominguez, Dummer, Eggiak, Fennell, Roddy, Schroter, Shaw, Snover, Starzl, Starzl, Starzl, van Thiel, van Thiel, Wajszczuk, Williams, Zajko   +17 more
core   +1 more source

Biliary tract cancer

European Journal of Surgical Oncology
Biliary tract cancers comprise a heterogeneous collection of malignancies usually described as cholangiocarcinoma of the intra- or extrahepatic bile duct, including perihilar cholangiocarcinoma and gallbladder cancer.A review of pertinent parts of the ESSO core curriculum for the UEMS diploma targets (Fellowships exam, EBSQ), based on updated and ...
Søreide, Kjetil, Dopazo, Cristina, Berrevoet, Frederik, Carrion-Alvarez, Lucia, Diaz-Nieto, Rafael, Andersson, Bodil, Stättner, Stefan, On behalf of the joint ESSO-EAHPBA-UEMS core curriculum working group, [missing]   +7 more
openaire   +5 more sources

Hepatic progenitor cells from adult human livers for cell transplantation. [PDF]

, 2008
Objective: Liver regeneration is mainly based on cellular self-renewal including progenitor cells. Efforts have been made to harness this potential for cell transplantation, but shortage of hepatocytes and premature differentiated progenitor cells ...
Aurich, H., Brockhoff, G., Christ, B., Jauch, Karl-Walter, Kirchner, S., Kunz-Schughart, L.A., Lichtenauer, M., Schlitt, H.-J., Stock, P., Thasler, Wolfgang E., Weiss, T.S.   +10 more
core   +1 more source

Integrative analyses of bulk and single-cell transcriptomics reveals the infiltration and crosstalk of cancer-associated fibroblasts as a novel predictor for prognosis and microenvironment remodeling in intrahepatic cholangiocarcinoma

Journal of Translational Medicine
Background Intrahepatic cholangiocarcinoma (ICC) is a highly malignant neoplasm and characterized by desmoplastic matrix. The heterogeneity and crosstalk of tumor microenvironment remain incompletely understood.
Yan-Jie Zhong, Xi-Mei Luo, Fei Liu, Zhi-Qiang He, Si-Qi Yang, Wen-Jie Ma, Jun-Ke Wang, Yu-Shi Dai, Rui-Qi Zou, Ya-Fei Hu, Tian-Run Lv, Fu-Yu Li, Hai-Jie Hu   +12 more
doaj   +1 more source

Correlation of mechanical factors and gallbladder pain [PDF]

, 2008
Acalculous biliary pain occurs in patients with no gallstones, but is similar to that experienced by patients with gallstones. Surgical removal of the gallbladder (GB) in these patients is only successful in providing relief of symptoms to about half of ...
Bird, N.C., Chin, S.B., Hill, N.A., Johnson, A.G., Li, W.G., Luo, X.Y., Smythe, A.   +6 more
core   +3 more sources

Short-term and Long-term Clinical Outcomes of Combined Caudate Lobectomy for Intrahepatic Cholangiocarcinoma Involving the Hepatic Hilus: A Propensity Score Analysis

Gut and Liver
Background/Aims: Extended hepatectomy combined with caudate lobe resection has been approved for the radical resection of hilar cholangiocarcinoma. There was a lack of credible research on the clinical value of caudate lobectomy (CL) for intrahepatic ...
Di Zeng, Yaoqun Wang, Ningyuan Wen, Bei Li, Nansheng Cheng, Jiong Lu   +5 more
doaj   +1 more source

Surgical complications in human orthotopic liver transplantation. [PDF]

, 1987
Between March 1, 1980 and December 31, 1984, 393 orthotopic liver transplantations (OLT) were performed in 313 consecutive recipients. Technical complications were responsible for a substantial morbidity (41/393 allograft loss--10.4%) and mortality (26 ...
Gordon, RD, Iwatsuki, S, Lerut, J, Starzl, TE   +3 more
core