Results 41 to 50 of about 1,047,340 (417)
Organoids: The current status and biomedical applications
Organoids are three‐dimensional (3D) miniaturized versions of organs or tissues that are derived from cells with stem potential and can self‐organize and differentiate into 3D cell masses, recapitulating the morphology and functions of their in vivo ...
Siqi Yang+9 more
doaj +1 more source
Bile dynamics within the biliary tract and microfluidic-based bile component detection: A review [PDF]
Bilestones are solid masses found in the gallbladder or biliary tract, which block the normal bile flow and eventually result in severe life-threatening complications. Studies have shown that bilestone formation may be related to bile flow dynamics and the concentration level of bile components.
arxiv
Circulating Tumor DNA in Biliary Tract Cancer: Current Evidence and Future Perspectives
Peripheral blood of cancer patients “physiologically” presents cells and cellular components deriving from primary or metastatic sites, including circulating tumor cells (CTCs), circulating free DNA (cfDNA) and exosomes containing proteins, lipids and ...
A. Rizzo+3 more
semanticscholar +1 more source
Chemotherapy for Biliary Tract Cancer in 2021
Biliary tract cancer refers to a group of malignancies including cholangiocarcinoma, gallbladder cancer, and ampullary cancer. While surgical resection is considered the only curative treatment, postoperative recurrence can sometimes occur.
Takashi Sasaki+4 more
semanticscholar +1 more source
Matroids over Skew Tracts [PDF]
Matroids over tracts provide an algebraic framework simultaneously generalizing the notions of matroids, oriented matroids, and valuated matroids, presented by Baker and Bowler. Pendavingh partially extended this theory to skew hyperfields and presented a new axiom system in terms of quasi-Pl\"ucker coordinates.
arxiv +1 more source
Molecular profile of BRCA-mutated biliary tract cancers
Introduction Prognosis of biliary tract cancers (BTC) remains dismal and novel treatment strategies are needed to improve survival. BRCA mutations are known to occur in BTC but their frequency and the molecular landscape in which they are observed in ...
G. Spizzo+21 more
semanticscholar +1 more source
Importance Administration of gemcitabine-cisplatin, the current standard therapy for advanced biliary tract cancers, results in median progression-free survival and overall survival of 8.0 and 11.7 months, respectively.
R. Shroff+12 more
semanticscholar +1 more source
Immunotherapy in Biliary Tract Cancer: Worthy of a Second Look
Although immune checkpoint inhibitors (ICIs) have revolutionized the treatment landscape of several malignancies, the role of immunotherapy in biliary tract cancer (BTC) is currently under investigation and ICIs are still looking for their niche in this ...
A. Ricci, A. Rizzo, G. Brandi
semanticscholar +1 more source
Immunotherapy in Advanced Biliary Tract Cancers
Simple Summary A new era has emerged in oncology in the last ten years with the development of immune therapies. However, single-agent immune therapy such as immune checkpoint inhibitors seems to have a limited clinical activity in biliary tract cancers ...
A. Boilève+5 more
semanticscholar +1 more source
Biliary tract complications in human orthotopic liver transplantation [PDF]
The results of 393 consecutive orthotopic liver transplants in 313 patients were reviewed to determine the incidence of primary biliary tract complications.
Esquivel, CO+6 more
core +1 more source