Results 61 to 70 of about 1,090,016 (327)

Surgical complications in human orthotopic liver transplantation. [PDF]

, 1987
Between March 1, 1980 and December 31, 1984, 393 orthotopic liver transplantations (OLT) were performed in 313 consecutive recipients. Technical complications were responsible for a substantial morbidity (41/393 allograft loss--10.4%) and mortality (26 ...
Gordon, RD, Iwatsuki, S, Lerut, J, Starzl, TE   +3 more
core  

Targeted Therapies in Advanced Biliary Tract Cancer: An Evolving Paradigm

Cancers, 2020
Biliary tract cancers (BTCs) are a heterogeneous group of adenocarcinomas that originate from the epithelial lining of the biliary tree. BTCs are characterized by presentation with advanced disease precluding curative surgery, rising global incidence ...
S. Chakrabarti, M. Kamgar, A. Mahipal
semanticscholar   +1 more source

Oral Dosed Organo‐Silica Nanoparticles Restore Glucose Homeostasis and β‐Cell Function in Diabetes Rats

Advanced Functional Materials, EarlyView.
An oral nanoplatform, MOP@T@D, which can maintain glucose homeostasis and restore islet β cells in diabetic rats is developed. It achieves efficient intestinal absorption and liver‐targeted delivery. The nanoparticle disintegrates only in response to hyperglycemia to release insulin on demand and provides antioxidant protection through selenoprotein ...
Chenxiao Chu, Mingli Wei, Che Bian, Xiaoshuang Bi, Yaxin Deng, Peifu Xiao, Jiansong Zhao, Yuying Wang, Haibing He, Jingxin Gou, Tian Yin, Xing Tang, Li Yang, Hongbo Zhang, Yu Zhang   +14 more
wiley   +1 more source

Harnessing Next‐Generation 3D Cancer Models to Elucidate Tumor‐Microbiome Crosstalk

Advanced Healthcare Materials, EarlyView.
Centralizes the microbiome within 3D tumor‐microbiome model platforms, including spheroids, organoids, 3D‐bioprinted constructs, and microfluidic chips, each enabling structured host‐tumor‐microbe studies. These systems support bacterial colonization, facilitating investigation of microbial impacts on tumor growth, immunity, and therapy. The microbiome
Marina Green Buzhor, Giuseppe Longobardi, Or Kandli, Anne Krinsky, Opal Avramoff, Anshika Katyal, Koren Salomon, Adan Miari, Dana Venkert, Tania T. Barnatan, América García Alvarado, Shahar Greenberg, Ronit Satchi‐Fainaro   +12 more
wiley   +1 more source

Adult liver transplantation: An analysis of the early causes of death in 40 consecutive cases [PDF]

, 1986
One hundred twenty‐nine adult patients who received an orthotopic liver transplantation and survived at least 24 hr after surgery were evaluated. During the period of follow‐up, 48 of the 129 patients (37%) died.
Calne, Demetris, Dominguez, Dummer, Eggiak, Fennell, Roddy, Schroter, Shaw, Snover, Starzl, Starzl, Starzl, van Thiel, van Thiel, Wajszczuk, Williams, Zajko   +17 more
core   +1 more source

Strategies to Improve the Lipophilicity of Hydrophilic Macromolecular Drugs

Advanced Healthcare Materials, EarlyView.
Hydrophilic macromolecular drugs can be successfully lipidized by covalent attachment of lipids, by hydrophobic ion pairing with negatively or positively charged surfactants, and by dry or wet reverse micelle formation. Lipophilicity enhancement of hydrophilic macromolecules has several benefits including stability and bioavailability improvement ...
Sera Lindner, Stefan Keim, Soheil Haddadzadegan, Odile Fernandez Romero, Katrin Zöller, Gabriel Stern, Ilaria Cesi, Krum Kafedjiiski, Andreas Bernkop‐Schnürch   +8 more
wiley   +1 more source

Cordycepin Induces S Phase Arrest and Apoptosis in Human Gallbladder Cancer Cells

Molecules, 2014
Gallbladder cancer is the most common malignant tumor of the biliary tract, and this condition has a rather dismal prognosis, with an extremely low five-year survival rate.
Xu-An Wang, Shan-Shan Xiang, Huai-Feng Li, Xiang-Song Wu, Mao-Lan Li, Yi-Jun Shu, Fei Zhang, Yang Cao, Yuan-Yuan Ye, Run-Fa Bao, Hao Weng, Wen-Guang Wu, Jia-Sheng Mu, Yun-Ping Hu, Lin Jiang, Zhu-Jun Tan, Wei Lu, Ping Wang, Ying-Bin Liu   +18 more
doaj   +1 more source

Application progress of CT radiomics in gastrointestinal stromal tumor

Shanghai Jiaotong Daxue xuebao. Yixue ban, 2023
Gastrointestinal stromal tumor (GIST) is the most common mesenchymal tumor in the gastrointestinal tract, with complex biological characteristics and varying risks, and the treatment methods and prognosis of patients with different risks are quite ...
MA Ben, ZHAO Cheng, SHU Yijun, DONG Ping
doaj   +1 more source

Pathologic analysis of liver transplantation for primary biliary cirrhosis [PDF]

, 1988
A retrospective histopathologic review of all pathologic specimens from 394 adult liver transplant patients was undertaken with clinical correlation to determine if primary biliary cirrhosis has affected the posttrans‐plant course compared to all other ...
Ballardini, Baum, Berg, Bernuau, Demetris, Demetris, Demetris, Demetris, Detre, Epstein, Epstein, Esquivel, Fennell, Fung, Haagsma, Iwatsuki, James, MacSween, McFarlane, McFarlane, Neuberger, Popper, Portmann, Portmann, Portmann, Vento   +25 more
core   +1 more source

Probiotic‐Based Materials as Living Therapeutics

Advanced Materials, EarlyView.
Recent advances in Engineered Living Materials are highlighted, integrating synthetic biology and advanced materials, with a focus on probiotic‐based therapeutics. Probiotic Living Materials hold great potential for biosensing, infection treatment, osteogenesis, wound healing, vaginal and gastrointestinal disorders, and cancer therapy. breakthroughs in
Laura Sabio, Graham J. Day, Manuel Salmeron‐Sanchez   +2 more
wiley   +1 more source