Results 171 to 180 of about 159,964 (350)

Phase IIb Trial for the Palliative Treatment of Patients With Primary Hepatic Malignancy Unable to Receive Curative Treatment: Efficacy of Colchicine

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT This trial was to evaluate the efficacy and the safety of colchicine for the palliative treatment of patients with primary hepatic malignancy unable to receive curative treatment. Forty hepatocellular carcinoma (HCC) patients and two intrahepatic cholangiocarcinoma (ICC) patients signed the informed consents.
Zu‐Yau Lin, Ming‐Lun Yeh, Po‐Cheng Liang, Shinn‐Cherng Chen, Chung‐Feng Huang, Jee‐Fu Huang, Chia‐Yen Dai, Ming‐Lung Yu, Wan‐Long Chuang   +8 more
wiley   +1 more source

Prognostic factors in patients with advanced biliary tract cancer (BTC) who showed durable disease control with first-line gemcitabine plus cisplatin (GemCis)

, 2018
Jaewon Hyung, Changhoon Yoo, K.-P. Kim, Bum Joon Kim, Jae Ho Jeong, Heung-Moon Chang, Baek‐Yeol Ryoo   +6 more
openalex   +1 more source

GERD and Upper Aerodigestive Tract Cancer Risk: A Systematic Review and Meta‐Analysis

The Laryngoscope, EarlyView.
ABSTRACT Objective Gastroesophageal reflux disease (GERD) is highly prevalent, yet its association with upper aerodigestive tract (UADT) cancers beyond esophageal adenocarcinoma remains incompletely defined. This systematic review and meta‐analysis aimed to quantify the risk of specific UADT cancers in individuals with GERD.
Janice Huang, Nicolas Jo, Garret Forman, Tonya Aaron, Sophia Peifer, Soumil Prasad, Luke van Leeuwen, Laura Wild, Nicholas DiStefano, Zhibin Chen, Elizabeth Franzmann   +10 more
wiley   +1 more source

Tumor Mutational Burden as a Biomarker for Advanced Biliary Tract Cancer [PDF]

, 2021
Hong-Sik Kim, Hana Kim, Ryul Kim, Hyunji Jo, Hye Ryeon Kim, Joo-Hyun Hong, Joon Oh Park, Young Suk Park, Seung Tae Kim   +8 more
openalex   +1 more source

Beyond PD‐1/PD‐L1: New Immune Checkpoints and Therapeutic Combinations in Cancer Immunotherapy

Medicine Bulletin, EarlyView.
ABSTRACT Recently, immune checkpoint inhibitors (ICIs), particularly PD‐1/PD‐L1 and CTLA‐4 inhibitors, have revolutionized cancer treatment, significantly improving survival rates for various malignancies. However, ICI therapies targeting single checkpoints on T cells still face numerous challenges, such as low response rates and post‐treatment ...
Yangyang Li, Zizhen Kang, Yanyun Du
wiley   +1 more source

Efficacy and Safety of the MDM2–p53 Antagonist Brigimadlin (BI 907828) in Patients with Advanced Biliary Tract Cancer: A Case Series

Noboru Yamamoto, Anthony W. Tolcher, Navid Hafez, Iwona Ługowska, Rodryg Ramlau, Teresa Macarulla, Junxian Geng, Jian Li, Michael Teufel, Angela Märten, Patricia LoRusso   +10 more
openalex   +2 more sources

Genetic associations of cholelithiasis and biliary tract cancer. [PDF]

Transl Oncol
Jiang Y, Chen H, Tian Q, Hu C, Wu Z, Yuan Y, Ouyang X, Chang K, Wu D, Chen J, Huang J, Chen R, Zheng S, Li L.   +13 more
europepmc   +1 more source

Incidence and Mortality Risks of Gastrointestinal Cancers During Working‐Age Period: Trends and Disparities in 204 Countries and Territories (1990–2021)

Med Research, EarlyView.
This comprehensive analysis of gastrointestinal (GI) cancer risk reveals that globally, one in 46 people will develop and one in 73 will die from GI cancers during working age (15–64 years), with 2021 incidence and mortality risks of 2.19% and 1.37%, respectively. Key findings demonstrate striking gender disparities, with males facing nearly double the
Yiming Song, Zhongge Ji, Xunbing Zhang, Qian Liang, Zeyu Li, Xiaojie Huang, Jinnan Chen, Yujie Zhou, Xinyuan Wang, Zhao Li, Liuyi Yang, Yixin Qian, Xiaolu Lin, Qingwei Zhang, Xiaobo Li   +14 more
wiley   +1 more source

Advancing Extracellular Vesicle Research: A Review of Systems Biology and Multiomics Perspectives

PROTEOMICS, EarlyView.
ABSTRACT Extracellular vesicles (EVs) are membrane‐bound vesicles secreted by various cell types into the extracellular space and play a role in intercellular communication. Their molecular cargo varies depending on the cell of origin and its functional state.
Gloria Kemunto, Samaneh Ghadami, Kristen Dellinger   +2 more
wiley   +1 more source

Molecular Profiling of Biliary Tract Cancers in African American and Caucasian Patients [PDF]

Zishuo Ian Hu, Dean C. Pavlick, Jeffrey S. Ross, Sunyoung S. Lee, Madhulika Eluri, Milind Javle   +5 more
openalex   +1 more source