Results 221 to 230 of about 193,970 (395)

Exploring the Role of TAS2Rs in Obesity: Insights From Human and Rat Models

Obesity, EarlyView.
ABSTRACT Objective Obesity is a chronic disease with various causes and diverse treatments, including dietary restriction and bariatric surgery. Bitter taste receptors (TAS2Rs), found in the oral cavity and gastrointestinal tract (GIT), are implicated in digestive and metabolic regulation, but their role in obesity remains unclear.
Maria Descamps‐Solà, Florijan Jalševac, Adrià Vilalta, Margalida Fontcuberta, Harry Park, Carmen Aguilar, Teresa Auguet, Raúl Beltrán‐Debón, Esther Rodríguez‐Gallego, Montserrat Pinent, Ximena Terra, Anna Ardévol   +11 more
wiley   +1 more source

Leveraging Multimodal Foundation Models in Biliary Tract Cancer Research. [PDF]

Tomography
Singh Y, Andersen JB, Hathaway QA, Vera-Garcia DV, Keishing V, Venkatesh SK, Salehi S, Povero D, Wallace MB, Gores GJ, Wei Y, Horvat N, Erickson BJ, Quaia E.   +13 more
europepmc   +1 more source

A phase 1 dose-escalation and expansion study of binimetinib (MEK162), a potent and selective oral MEK1/2 inhibitor [PDF]

, 2017
et al,, Tan, Benjamin R
core   +2 more sources

Bile Acid Binding Resins Improve Glucagon Receptor Agonist‐Mediated Weight Loss in Diet‐Induced Obese Mice

Obesity, EarlyView.
ABSTRACT Objective Glucagon‐receptor (GCGR) agonism reguglates bile acid (BA) metabolism and promotes weight loss in diet‐induced obese (DIO) mice. Thus, we hypothesized that BA signaling contributes to GCGR‐stimulated weight loss. Methods To test this hypothesis, we utilized BA‐binding resins (BARs; colesevelam [Colsv] and cholestyramine [Cstyr]) to ...
Teayoun Kim, Mackenzie J. Pearson, Huixian Hong, Shelly Nason, Khadija Seck, Jessica Antipenko, Natalie Presedo, Richard DiMarchi, William C. Roell, Kirk Habegger   +9 more
wiley   +1 more source

Hyponatremia predicts immunotherapy resistance in biliary tract cancer. [PDF]

Hum Vaccin Immunother
Wang T, Lv Z, Fan R, Han W, Mei Q.
europepmc   +1 more source

Surgical management of biliary tract cancers

, 2016
Mark Fairweather, Vinod P. Balachandran, Michael I. D’Angelica   +2 more
openalex   +1 more source

Gemcitabine-based versusfluoropyrimidine-based chemotherapy with or without platinum in unresectable biliary tract cancer: a retrospective study [PDF]

, 2008
Mi‐Jung Kim, Do‐Youn Oh, Se‐Hoon Lee, Dong‐Wan Kim, Seock‐Ah Im, Tae‐You Kim, Dae Seog Heo, Yung‐Jue Bang   +7 more
openalex   +1 more source

Supplementary Table from Phase II Study of Ramucirumab in Advanced Biliary Tract Cancer Previously Treated By Gemcitabine-Based Chemotherapy

, 2023
Sunyoung Lee, Rachna T. Shroff, Shalini Makawita, Lianchun Xiao, Anaemy Danner De Armas, Priya Bhosale, Kavitha Reddy, Ahmed Shalaby, Kanwal Raghav, Shubham Pant, Robert A. Wolff, Milind Javle   +11 more
openalex   +1 more source

Camrelizumab plus oxaliplatin‐based chemotherapy as first‐line therapy for advanced biliary tract cancer: A multicenter, phase 2 trial

International Journal of Cancer, 2021
Xinni Chen, S. Qin, S. Gu, Z. Ren, Zhendong Chen, J. Xiong, Ying Liu, Z. Meng, Xiao Zhang, Linna Wang, Xiaojing Zhang, J. Zou   +11 more
semanticscholar   +1 more source

Advancing Extracellular Vesicle Research: A Review of Systems Biology and Multiomics Perspectives

PROTEOMICS, EarlyView.
ABSTRACT Extracellular vesicles (EVs) are membrane‐bound vesicles secreted by various cell types into the extracellular space and play a role in intercellular communication. Their molecular cargo varies depending on the cell of origin and its functional state.
Gloria Kemunto, Samaneh Ghadami, Kristen Dellinger   +2 more
wiley   +1 more source