Results 241 to 250 of about 193,970 (395)

Efficacy of concurrent chemoradiotherapy with 5-fluorouracil or gemcitabine in locally advanced biliary tract cancer

, 2013
Seung Woo Yi, Dae Ryong Kang, Kyung Sik Kim, Mi‐Suk Park, Jinsil Seong, Jeong Youp Park, Seungmin Bang, Si Young Song, Jae Bock Chung, Seung Woo Park   +9 more
openalex   +2 more sources

Characterizing Apixaban Pharmacokinetics Through Physiologically‐Based Pharmacokinetic Modeling: Critical Role of Biliary Secretion and Enterohepatic Circulation in Humans

CPT: Pharmacometrics &Systems Pharmacology, EarlyView.
ABSTRACT Apixaban, a factor Xa inhibitor, is a direct oral anticoagulant with a well‐balanced elimination; it is eliminated evenly via feces, urine (with no active secretion), and as metabolites after oral administration. The common understanding is that biliary secretion and enterohepatic circulation (EHC) of apixaban are limited in humans, and that ...
Toshiaki Tsuchitani, Wen Kou, Masatoshi Tomi, Yuichi Sugiyama   +3 more
wiley   +1 more source

Comparison of 5-Fluorouracil/Leucovorin and Capecitabine as Adjuvant Therapies in Biliary Tract Cancer. [PDF]

J Gastroenterol Hepatol
Lee TS, Choi YH, Kim JY, Lee MH, Paik KH, Cho IR, Kwon WI, Lee SH, Lee IS, Lee MA, Jang JY, Ryu JK, Kim YT, Paik WH.   +13 more
europepmc   +1 more source

PEARL: Protein Eluting Alginate with Recombinant Lactobacilli

Small, EarlyView.
Probiotic lactobacilli meet engineered living materials: This study introduces PEARL (protein eluting alginate with recombinant lactobacilli), an innovative engineered living material combining Lactiplantibacillus plantarum and alginate beads for controlled protein release.
Varun Sai Tadimarri, Marc Blanch‐Asensio, Ketaki Deshpande, Jonas Baumann, Carole Baumann, Rolf Müller, Sara Trujillo, Shrikrishnan Sankaran   +7 more
wiley   +1 more source

Data from Serum IL6 as a Prognostic Biomarker and IL6R as a Therapeutic Target in Biliary Tract Cancers

, 2023
Dan Høgdall, Colm J. O’Rourke, Christian Dehlendorff, Ole Larsen, Lars Henrik Jensen, Astrid Z. Johansen, Hien Dang, Valentina M. Factor, Mie Grunnet, Morten Mau‐Sørensen, Douglas V.N.P. Oliveira, Dorte Linnemann, Mogens K. Boisen, Xin Wei Wang, Julia S. Johansen, Jesper B. Andersen   +15 more
openalex   +1 more source

Bioengineered Bacterial Vesicles and Biomimetic Hybrids Eliminate Biofilms and Balance the Gut Microbiome

Small, EarlyView.
Biomimetic nanocarriers based on liposomes and Myxobacteria outer‐membrane vesicles (OMVs) are effective antibiotic delivery systems. Hybrids have a higher drug loading and can target intracellular pathogens, while OMVs evade immune clearance. Biomimetic nanoantibiotics effectively eliminate the biofilms of Gram‐negative bacteria. Besides, Myxobacteria
Leila Pourtalebi Jahromi, Benedikt Kronast, Jennifer Munkert, Lorenzo Sana, Marcus Koch, Heike Danzer, Sirka Dormeyer, Shuhan Jiang, Fabian Herrmann, Matthias Weiler, Anna Kashkanova, Vahid Sandoghdar, Mario M. Zaiss, Gregor Fuhrmann   +13 more
wiley   +1 more source

GLIM Criteria as Prognostic Factor in Patients Undergoing Adjuvant S-1 Chemotherapy for Biliary Tract Cancer. [PDF]

Cancer Diagn Progn
Konaka R, Yanagimoto H, Tsugawa D, Akita M, Mizumoto T, Yoshida T, Sou S, Ishida J, Nanno Y, Urade T, Fukushima K, Gon H, Komatsu S, Asari S, Kido M, Toyama H, Fukumoto T.   +16 more
europepmc   +1 more source

Molecular targeted therapies: ready for "prime time" in biliary tract cancer.

Journal of Hepatology, 2020
A. Lamarca, J. Barriuso, M. McNamara, J. Valle   +3 more
semanticscholar   +1 more source

Nanomedicine for Oral Delivery: Strategies to Overcome the Biological Barriers

Small Methods, EarlyView.
Oral delivery is a preferred administration route for many clinical applications, valued for its strong patient compliance. In this review, how nanoparticles are engineered and deployed to overcome the gastrointestinal barriers that impede clinical translation of oral delivery formulations is examined.
Luke J. Kubiatowicz, Nima Pourafzal, Audrey T. Zhu, Zhongyuan Guo, Ronnie H. Fang, Liangfang Zhang   +5 more
wiley   +1 more source

Therapeutic T cells with 3-in-1 strategy for the treatment of biliary tract cancer. [PDF]

Cell Rep Med
Wan X, Zhao J, Yang X, Mou X, Liu B, Gao B, Gu W, Zhao H.   +7 more
europepmc   +1 more source