Results 341 to 350 of about 193,970 (395)
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Current Opinion in Gastroenterology, 2000
Investigation into the molecular and cellular biology of carcinogenesis continues to elucidate potential mechanisms for the initiation and progression of biliary tract cancer. The potential role of cell cycle regulators, such as Fas ligand, has been examined in the etiology of bile duct carcinoma.
J N, Cormier, J N, Vauthey
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Investigation into the molecular and cellular biology of carcinogenesis continues to elucidate potential mechanisms for the initiation and progression of biliary tract cancer. The potential role of cell cycle regulators, such as Fas ligand, has been examined in the etiology of bile duct carcinoma.
J N, Cormier, J N, Vauthey
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Durvalumab: an investigational anti-PD-L1 antibody for the treatment of biliary tract cancer
Expert Opinion on Investigational Drugs, 2021Introduction: The prognosis of patients with advanced biliary tract cancer (BTC) remains dismal, with a 5-year overall survival rate of less than 10%.
A. Rizzo, A. Ricci, G. Brandi
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New England Journal of Medicine, 1999
In the United States, an estimated 20,000 new cases of liver and biliary tract cancer are diagnosed annually.1 Biliary tract cancer is the second most common primary hepatobiliary cancer, after hepatocellular cancer. Approximately 7500 new cases of biliary tract cancer are diagnosed per year; about 5000 of these are gallbladder cancer, and between 2000
P C, de Groen +4 more
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In the United States, an estimated 20,000 new cases of liver and biliary tract cancer are diagnosed annually.1 Biliary tract cancer is the second most common primary hepatobiliary cancer, after hepatocellular cancer. Approximately 7500 new cases of biliary tract cancer are diagnosed per year; about 5000 of these are gallbladder cancer, and between 2000
P C, de Groen +4 more
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Precision Medicine in Biliary Tract Cancer.
Journal of Clinical Oncology, 2022Precision medicine has become a dominant theme in the treatment of biliary tract cancers (BTCs). Although prognosis remains poor, technologies for improved molecular characterization along with the US Food and Drug Administration approval of several ...
A. Scott, R. Sharman, R. Shroff
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Radiotherapy for Biliary Tract Cancers
Seminars in Radiation Oncology, 2018Biliary tract cancers (BTCs), including intrahepatic, perihilar and distal cholangiocarcinomas, and gallbladder cancers, are a heterogeneous cohort of tumors that tend to present with advanced stage and with high rates of recurrence after surgical resection.
Florence K, Keane +2 more
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Pitfalls, challenges, and updates in adjuvant systemic treatment for resected biliary tract cancer
Expert Review of Gastroenterology & Hepatology, 2021Introduction: Unfortunately, potentially curative surgical resection is possible in approximately the 25% of biliary tract cancer (BTC) patients at diagnosis, and even following radical surgery, relapse rates remain high.
A. Rizzo, G. Brandi
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Advanced Biliary Tract Cancers
American Society of Clinical Oncology Educational Book, 2012Overview: Single-agent management of metastatic biliary tract cancers with 5-fluorouracil (5-FU) or gemcitabine has shown limited efficacy, although 5-FU has been shown to be more effective than best supportive care alone. An analysis of phase II trials has suggested that platinums enhanced the efficacy of single-agent fluoropyrimidines. In a phase III
Laura Williams, Goff, Jordan D, Berlin
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Hepatology, 2021
Biliary tract cancer (BTC) exhibits diverse molecular characteristics. However, reliable biomarkers that predict therapeutic responses are yet to be discovered.
Jihoon G. Yoon +12 more
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Biliary tract cancer (BTC) exhibits diverse molecular characteristics. However, reliable biomarkers that predict therapeutic responses are yet to be discovered.
Jihoon G. Yoon +12 more
semanticscholar +1 more source
Journal of hepato-biliary-pancreatic sciences
Although surgical resection is the only curative treatment for biliary tract cancer, in some cases, the disease is diagnosed as unresectable at initial presentation. There are few reports of conversion surgery after the initial treatment for unresectable
Y. Yabushita +28 more
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Although surgical resection is the only curative treatment for biliary tract cancer, in some cases, the disease is diagnosed as unresectable at initial presentation. There are few reports of conversion surgery after the initial treatment for unresectable
Y. Yabushita +28 more
semanticscholar +1 more source
Current Opinion in Gastroenterology, 1995
Biliary tract cancer is a rare cancer in most parts of the world, but it is relatively common in some countries and ethnic groups, such as Japan, Central and South America, eastern Europe and in American Indians, and Hispanics. In some countries, such as Japan, Sweden, Finland and Italy, the age adjusted mortality of biliary tract cancer has been ...
Jean-Nicolas Vauthey, Paul Dudrick
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Biliary tract cancer is a rare cancer in most parts of the world, but it is relatively common in some countries and ethnic groups, such as Japan, Central and South America, eastern Europe and in American Indians, and Hispanics. In some countries, such as Japan, Sweden, Finland and Italy, the age adjusted mortality of biliary tract cancer has been ...
Jean-Nicolas Vauthey, Paul Dudrick
openaire +3 more sources