Results 141 to 150 of about 61,504 (314)
Classically described in the group of non‐cirrhotic portal hypertension, obliterative portal venopathy (OPV) causes are still unknown. Our aim is to describe the characteristics of 43 OPV patients and potential risk factors. Clinically significant portal hypertension was found in 28% of cases. The most frequent indication for liver biopsy was elevation
Vinícius Nunes+7 more
wiley +1 more source
Sonographic findings of biliary tract disease [PDF]
Duck Soo Chung+4 more
openalex +1 more source
Cuproplasia and cuproptosis, two sides of the coin
Abstract Copper is an essential micronutrient in the human body, mainly acting as a crucial cofactor required for a wide range of physiological processes across nearly all cell types. Recent advances revealed that tumor cells seize copper to fulfill their rapid proliferation, metastasis, immune evasion, and so on by reprogramming the copper regulatory ...
Kaizhong Lu+4 more
wiley +1 more source
Endoscopic CBD stone removal is more difficult with stones larger than 2 mm than with distal CBD diameter or round or square‐shaped stones. Therefore, endoscopic large papillary balloon dilatation (ELPBD) is probably more required for stones larger than 2 mm than for distal CBD; likewise, round or square‐shaped stones are likely more required for ELPBD
Chote Wongkanong+4 more
wiley +1 more source
Copper in cancer: friend or foe? Metabolism, dysregulation, and therapeutic opportunities
Abstract Copper, one of the essential nutrients for the human body, acts as an electron relay in multiple pathways due to its redox properties. Both deficiencies and excesses of copper lead to cellular fragility. Therefore, it can manifest pro‐ and anti‐cancer properties in tumors. Therefore, it is crucial to clarify the copper activity within the cell.
Dan Shan+13 more
wiley +1 more source
A Model-Based Analysis of GC-Biased Gene Conversion in the Human and Chimpanzee Genomes [PDF]
GC-biased gene conversion (gBGC) is a recombination-associated process that favors the fixation of G/C alleles over A/T alleles. In mammals, gBGC is hypothesized to contribute to variation in GC content, rapidly evolving sequences, and the fixation of deleterious mutations, but its prevalence and general functional consequences remain poorly understood.
arxiv
Abstract Background The epidemiological profiles of gastrointestinal (GI) cancers vary across countries and over time, largely reflecting variations in risk factors and screening practices. We aimed to provide an overview of the current global burden of the five major types of GI cancers and conduct an updated evaluation of the long‐term trends of GI ...
Mengmeng Li, Sumei Cao, Rui‐Hua Xu
wiley +1 more source
Ioka and colleagues present the results of a phase III study comparing gemcitabine and cisplatin plus S‐1 (GCS) with gemcitabine and cisplatin for unresectable or recurrent biliary tract cancer. GCS demonstrated survival benefits and a higher response rate, and could be the new standard chemotherapy for advanced biliary tract cancer.
Tatsuya Ioka+21 more
wiley +1 more source
Supplementary Figure Legends from Long-term Vaccination with Multiple Peptides Derived from Cancer-Testis Antigens Can Maintain a Specific T-cell Response and Achieve Disease Stability in Advanced Biliary Tract Cancer [PDF]
Atsushi Aruga+7 more
openalex +1 more source