Results 161 to 170 of about 346,538 (383)

Efficacy and safety of glecirasib in solid tumors with KRAS G12C mutation: A pooled analysis of two phase I/II trials

open access: yesCancer Communications, EarlyView.
Abstract Background Glecirasib, an inhibitor of Kirsten rat sarcoma viral oncogene homolog glycine‐to‐cysteine substitution at codon 12 (KRAS G12C), has exhibited clinical activity in non‐small‐cell lung cancer (NSCLC) and colorectal cancer (CRC).
Jian Li   +31 more
wiley   +1 more source

Intranuclear paraspeckle‐circular RNA TACC3 assembly forms RNA‐DNA hybrids to facilitate MASH‐related hepatocellular carcinoma growth in an m6A‐dependent manner

open access: yesCancer Communications, EarlyView.
Abstract Background Metabolic dysfunction‐associated steatohepatitis (MASH) is anticipated to become the leading cause of hepatocellular carcinoma (HCC). Accumulating evidence indicates that N6‐methyladenosine (m6A)‐modified circular RNAs (circRNAs) play key roles in tumor malignant progression.
Jingbo Fu   +22 more
wiley   +1 more source

The role of ERCP in benign diseases of the biliary tract.

open access: yesGastrointestinal Endoscopy, 2015
K. Chathadi   +24 more
semanticscholar   +1 more source

Advances in radiopharmaceuticals for cancer radiotheranostics: CCK2R targeting as a paradigm for translational innovation

open access: yesCancer Communications, EarlyView.
Abstract Radiopharmaceuticals are reshaping the landscape of cancer therapy, offering a unique theranostic advantage that is becoming increasingly central to precision medicine. By labeling the same molecular scaffold with different radionuclides, these agents enable seamless integration of diagnostic imaging and targeted therapy.
Jing Li   +6 more
wiley   +1 more source

The Aging Gut–Brain Axis: Effects of Dietary Polyphenols and Metal Exposure

open access: yesChronic Diseases and Translational Medicine, EarlyView.
The influence of gut microbiota on brain health ABSTRACT Diet provides essential metals, which are required for the growth, development, and well‐functioning of the body. Nonetheless, some natural and human activities add toxic heavy metals to the diet, consequently introducing them to our bodies, resulting in several disorders and death. The intestine,
Luqi Cao   +7 more
wiley   +1 more source

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