Results 161 to 170 of about 347,609 (391)

A 2‐Part, Open‐Label, Phase 1 Bioequivalence and Food‐Effect Study of Ubrogepant in Healthy Adult Participants

open access: yesClinical Pharmacology in Drug Development, EarlyView.
Abstract This Phase 1 study of ubrogepant was conducted to establish the bioequivalence (BE) of the 50‐ and 100‐mg to‐be‐marketed (TBM) tablet formulations with the clinical trial (CT) 100‐mg tablet formulation and evaluate the food effect on the bioavailability of the 100‐mg TBM tablet. This 2‐part study enrolled healthy participants aged 18‐45 years.
Ramesh Boinpally, Joel M. Trugman
wiley   +1 more source

Intestinal microbiota and biliary system diseases

open access: yesFrontiers in Cellular and Infection Microbiology
IntroductionThe incidence of biliary system diseases has been continuously increasing in the past decade. Biliary system diseases bring a heavy burden to humanity and society. However, the specific etiology and pathogenesis are still unknown. The biliary
Hua Wang   +5 more
doaj   +1 more source

Global, regional, and national quality of care of gallbladder and biliary tract cancer: a systematic analysis for the global burden of disease study 1990–2017 [PDF]

open access: gold, 2021
Javad Khanali   +14 more
openalex   +1 more source

Night‐Time Chronotherapy with Methylprednisolone Prevents an Acute Rejection in Pediatric Patients with Liver Transplantation: A Randomized Clinical Trial

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Concept of methylprednisolone chronotherapy to prevent acute rejections. While endogenous cortisol secretion rises in the early morning, the number of lymphocytes in the blood is higher at night, thus exhibiting an antiphase pattern to cortisol secretion. Therefore, compared with the daytime, the infiltration of lymphocytes into immune‐reactive tissues
Kentaro Ushijima   +11 more
wiley   +1 more source

Sonographic findings of biliary tract disease [PDF]

open access: bronze, 1983
Duck Soo Chung   +4 more
openalex   +1 more source

A Novel Plant‐Based Food to Enlarge the Access of Healthy Bioactive Compounds Typical of the Mediterranean Diet to Non‐Adherent People

open access: yesFood Frontiers, EarlyView.
The study showed that the intake of a novel plant‐based Mediterranean Diet‐based food (MD‐based food), which pooled different bioactive compounds characteristic of the Mediterranean Diet, in vitro orchestrated promising changes in the gut microbiota, microbiome and metabolome.
Andrea Polo   +14 more
wiley   +1 more source

Functional Disorders of the Biliary Tract and Cholelithiasis: Analysis of a Possible Relationship

open access: yesРоссийский журнал гастроэнтерологии, гепатологии, колопроктологии
Aim: Diagnostic criteria for functional disorders of the biliary tract are presented in the materials of the Rome IV consensus, as well as expert councils of Russian and foreign specialists.
Yu. O. Shulpekova   +2 more
doaj   +1 more source

An inclusive insight on dietary resistant protein and protein hydrolysates: Structural intricacy, bioactivity and benefits on human health

open access: yesFood Biomacromolecules, EarlyView.
Abstract This assessment explores the health benefits of resistant proteins and protein hydrolysates in human nutrition, highlighting their bioactive properties and amino acid compositions. Resistant proteins, which withstand digestion and operate comparably to dietary fibre and protein hydrolysates, obtained from enzymatic breakdown of proteins ...
Mohan Das   +7 more
wiley   +1 more source

Older adults living with gastrointestinal cancers in 2021

open access: yes
Cancer Communications, EarlyView.
Pojsakorn Danpanichkul   +15 more
wiley   +1 more source

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