Results 201 to 210 of about 61,504 (314)

Structures and functions of cilia during vertebrate embryo development

Molecular Reproduction and Development, Volume 89, Issue 12, Page 579-596, December 2022., 2022
Abstract Cilia are hair‐like structures that project from the surface of cells. In vertebrates, most cells have an immotile primary cilium that mediates cell signaling, and some specialized cells assemble one or multiple cilia that are motile and beat synchronously to move fluids in one direction.
Jeffrey D. Amack
wiley   +1 more source

Bacteria and disease of the biliary tract. [PDF]

Gut, 1971
openaire   +2 more sources

Plant extracellular vesicles: A promising bionic medicine platform for disease treatment and drug delivery

Interdisciplinary Medicine, EarlyView.
We introduced the basic characterization and isolation methods of PEVs, reviewed the PEVs‐related articles pertaining to disease therapy and drug delivery system, and summarized the drug loading methods, storage techniques, and engineering modification strategies of the carrier, to establish a safer, more efficient and more affordable approach for ...
Jichun Yang, Yuhan Wang, Yunqian Fu, Sitong Wang, Yao Luo, Xin Cui, Chenyu Sun, Jianing Ji, Jiaxi Mo, Yang Wang, Yilin Liu, Xinghong Hu, Xiaohui Chen, Yimin Jia, Yang Luo   +14 more
wiley   +1 more source

CAQ Corner: Immune‐mediated complications

, 2022
Liver Transplantation, EarlyView.
Mary Thomson, John R. Lake
wiley   +1 more source

Engineered strategies for the allergic disease therapy

Interdisciplinary Medicine, EarlyView.
Allergic diseases exist widely across the globe and now there are very limited therapeutics for the treatment of these diseases. In this review, we summarize the recent advances in engineering strategies including nanoemulsion and hydrogel to improve the therapeutic efficacy of allergen‐specific immunotherapy with decreased side effects and long‐term ...
Yun Tian, Xin Wu, Xiaoqi Sun, Lei Rong, Kai Han   +4 more
wiley   +1 more source

Safety Evaluation of Serendipity Berry Sweet Protein From Komagataella phaffii

Journal of Applied Toxicology, EarlyView.
ABSTRACT Serendipity Berry Sweet Protein (sweelin) is a novel hyper‐sweet thermophilic protein designed using Artificial Intelligence Computational Protein Design (AI‐CPD) to improve the stability and sensory profile of the protein found in serendipity berry (Dioscoreophyllum cumminsii).
Yael Lifshitz, Shira Paz, Rotem Saban, Inbar Zuker, Hagay Shmuely, Katy Gorshkov, Jwar Meetro, Shahrzad Tafazoli, Trung Vo, Gabriela Amiram, Carmit Shani Levi, Uri Lesmes, Ilan Samish   +12 more
wiley   +1 more source

The Combination of Active‐Targeted Photodynamic Therapy and Photoactivated Chemotherapy for Enhanced Cancer Treatment

Journal of Biophotonics, EarlyView.
Photoactivated chemotherapy (PACT), an oxygen‐independent light‐based therapy, utilizes chemotherapeutic regimens that remain inert until exposed to light, allowing target‐specific activation while minimizing off‐target toxicity. The integration of these techniques has the potential to improve selectivity and yield synergistic cytotoxic effects that ...
Nkune Williams Nkune, Heidi Abrahamse
wiley   +1 more source

PERSPECTIVE FOR EVALUATION OF MICRORNA IN PLASMA AND BILE FOR DIFFERENTIAL DIAGNOSIS OF OBSTRUCTIVE BILIARY TRACT DISEASE

, 2019
O. M. Terletskiy, V. І. Коlomiytsev, О. V. Lukavetskiy, M. M. Bufan   +3 more
openalex   +1 more source

A Large‐Scale Retrospective Study of Serum Des‐Gamma‐Carboxy Prothrombin as a Diagnostic Marker of HCC: Effect of Liver Function on Specificity

Journal of Clinical Laboratory Analysis, EarlyView.
Serum DCP may serve as an optimal biomarker for the diagnosis of HCC, but its accuracy appears to be influenced by liver function. The serum DCP may also serve as a biomarker for liver resection and interventional therapy of HCC, but is not promising for systemic treatment. ABSTRACT Background This retrospective multicenter study is aimed at evaluating
Hongying Bu, Weijia Luo, Wenli Tao, Chen Dong, Meifang Wang, Xu Ye, Xi Zeng, Boqing Wang, Chang Liu, Qi Yu, Deliang Cao, Hongyu Deng, Yuemin Nan   +12 more
wiley   +1 more source

Pharmacokinetics and Safety of Fenofibrate in Participants with Mild Hepatic Impairment or with Advanced Fibrosis due to Metabolic‐Associated Fatty Liver Disease

The Journal of Clinical Pharmacology, EarlyView.
Abstract Fenofibrate is contraindicated in patients with advanced hepatic fibrosis due to limited clinical data. We evaluated the pharmacokinetics and safety of fenofibrate in participants with mild hepatic impairment (phase 1 study) or advanced fibrosis due to metabolic‐associated fatty liver disease (MAFLD; phase 2a study).
Islam R. Younis, Elijah J. Weber, Cara Nelson, Ann R. Qin, Timothy R. Watkins, Ahmed A. Othman   +5 more
wiley   +1 more source