Results 221 to 230 of about 88,303 (317)

Factors in the development of liver transplantation [PDF]

open access: yes, 1985
Esquivel, CO   +7 more
core  

Current Cell/Organoid and Animal Models for Primary Sclerosing Cholangitis

open access: yesPortal Hypertension &Cirrhosis, EarlyView.
Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease with limited therapeutic options and a marked risk of progression to biliary fibrosis, cirrhosis, and malignancy. Progress in PSC research has been hindered by the lack of models that faithfully recapitulate the complex biliary microenvironment and disease heterogeneity ...
Qigu Yao   +4 more
wiley   +1 more source

Comparable Diagnostic Accuracy but Discordant Thresholds Between FibroTouch and FibroScan: A Biopsy‐Based Comparative Study

open access: yesPortal Hypertension &Cirrhosis, EarlyView.
In this biopsy‐controlled study, FibroTouch and FibroScan demonstrated comparable diagnostic accuracy for liver fibrosis staging (AUROCs > 0.900), but FibroTouch required consistently higher stiffness thresholds. These discrepancies were more pronounced in patients with MAFLD, highlighting the need for device‐specific cutoffs to avoid misclassification.
Min Wang   +8 more
wiley   +1 more source

Conservation status of species used in the UK herbal medicine industry

open access: yesPLANTS, PEOPLE, PLANET, EarlyView.
Given the ongoing biodiversity crisis, sustainable use and management of medicinal plants is critical. We assessed the conservation status, threats and conservation actions of 298 species sold by UK suppliers to medical herbalists. We found that most species used are unevaluated, representing a gap in conservation knowledge, and of those with ...
Isabella Flowers   +2 more
wiley   +1 more source

Analysis of C4 Concentrations to Predict Impact of Patient‐Reported Diarrhea Associated With the Ileal Bile Acid Transporter Inhibitor Linerixibat

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 596-605, March 2025.
ABSTRACT Linerixibat, an ileal bile acid transporter (IBAT) inhibitor, is being evaluated for the treatment of pruritus in primary biliary cholangitis (PBC). Diarrhea is commonly reported with this drug class as IBAT inhibition redirects bile acids (BA) to the colon.
Fernando Carreño   +4 more
wiley   +1 more source

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