Results 221 to 230 of about 2,597,010 (305)

Analysis of C4 Concentrations to Predict Impact of Patient‐Reported Diarrhea Associated With the Ileal Bile Acid Transporter Inhibitor Linerixibat

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 596-605, March 2025.
ABSTRACT Linerixibat, an ileal bile acid transporter (IBAT) inhibitor, is being evaluated for the treatment of pruritus in primary biliary cholangitis (PBC). Diarrhea is commonly reported with this drug class as IBAT inhibition redirects bile acids (BA) to the colon.
Fernando Carreño, Rashmi Mehta, Andrea Ribeiro de Souza, Jon Collins, Brandon Swift   +4 more
wiley   +1 more source

Diagnosis and treatment of cholecystogastric fistula: a case report. [PDF]

Front Surg
Chen B, Luo W.
europepmc   +1 more source

Systematic Review and Meta‐Analysis: Plant‐Based Therapy for Irritable Bowel Syndrome

Phytotherapy Research, EarlyView.
ABSTRACT Irritable bowel syndrome (IBS) is a common disorder of brain‐gut interaction that presents with abdominal pain, bloating associated with variable stool consistency. Many IBS patients prefer plant‐based preparations to pharmacological therapy; however, the utility of this approach is not well established.
Anselm Meyer, Jonas Auer, Lorena Cascant‐Ortolano, Niclas Schreiber, Amy Zimmermann‐Klemd, Carsten Gründemann, Philipp Busche, Jörg Schirra, Mark R. Fox   +8 more
wiley   +1 more source

Healthcare utilisation, expenditure, and admission-based mortality associated with paediatric hepatobiliary diseases in Thailand: a national database analysis (2015-2023). [PDF]

Lancet Reg Health Southeast Asia
Getsuwan S, Charoenwat B, Lertudomphonwanit C, Thepsuthammarat K, Treepongkaruna S, Sutra S.   +5 more
europepmc   +1 more source

Catechins and Their Effect on the Gut Microbiome in Health and Cancer

Phytotherapy Research, EarlyView.
ABSTRACT Catechins are a group of flavonoids found primarily in green tea, fruits, and berries; they play a significant role in the modulation of the gut microbiota, thereby having an impact on gut health and cancer prevention. Owing to their low bioavailability, catechins are transformed by the gut microbiota into various bioactive metabolites such as
Prakash Monika, Bindu Sadanandan, Honnamachanahalli Ramachandraiah Tejashree, Maitreyi Darbha, Kirti Gupta, Srinivas Reneeka   +5 more
wiley   +1 more source

Multimorbidity burden and patterns associated with DeepBrainNet-derived brain-age gap in dementia-free older adults: A community-based study. [PDF]

Alzheimers Dement
Liu X, Mao M, Liu C, Ai D, Wang J, Yu T, Han X, Ren Y, Han X, Dong Y, Song L, Tang S, Tian N, Cong L, Xu K, Du Y, Qiu C, Wang Y.   +17 more
europepmc   +1 more source

Pharmacokinetic and Pharmacodynamic Interactions Between Anti‐Asthma Drugs and Medicinal Plants: A Comprehensive Review

Phytotherapy Research, EarlyView.
ABSTRACT Asthma affects 260–300 million people worldwide. About 20%–35% of patients use medicinal plants with their asthma medication, often without telling their clinicians. Disclosure rates are low; up to 42% of asthma outpatients use herbal products, with no records in their charts.
Emine Kocyigit, Aylin Bülbül, Betul Kocaadam‐Bozkurt, Osman Bozkurt, Duygu Ağagündüz, Raffaele Capasso   +5 more
wiley   +1 more source

Microbiota in cholestatic diseases: crosstalk among bile composition, the biliary microbiome, and host immunity. [PDF]

Front Immunol
Yang Y, Ren L, Zhang Y, Wang X, Shang J, Zhang L.   +5 more
europepmc   +1 more source

Plant‐Derived Bioactives and PPAR Signaling in Functional Dyspepsia: Mechanistic Insights and Therapeutic Perspectives

Phytotherapy Research, EarlyView.
Functional dyspepsia involves duodenal barrier dysfunction, low‐grade immune activation and altered neuroimmune signalling. Various plant‐derived bioactives may modulate PPAR signalling, reduce inflammatory and oxidative stress, and support epithelial, immune, metabolic, and sensory homeostasis.
Irene Palenca, Emidio Scarpellini, Jan Tack, Pierluigi De Pierro, Giovanni Sarnelli, Giuseppe Esposito   +5 more
wiley   +1 more source

Clinical heterogeneity mapping and machine learning-based prediction of recurrence in gallstone disease: a retrospective cohort study of 9,939 patients. [PDF]

PeerJ
Zheng X, Yan Y, Bian C, Sun X, Bai X, Zhuang X, Zhang Y.   +6 more
europepmc   +1 more source