Results 41 to 50 of about 298,077 (320)

Global burden and cross-country inequalities in gallbladder and biliary tract cancer (1990-2021) with projections to 2050: insights from the global burden of disease study 2021. [PDF]

Front Med (Lausanne)
Xie D, Liu F, Zhou D, Zhu Q, Xiao F, Zhang K.   +5 more
europepmc   +2 more sources

Prognostic role of inflammatory and tumor biomarkers in hilar cholangiocarcinoma patients receiving postoperative adjuvant therapy

Frontiers in Oncology
BackgroundHilar cholangiocarcinoma (HCCA) is an aggressive cancer with poor prognosis after surgery. The systemic immune-inflammation index (SII) has been proposed as a prognostic marker, but its relationship with other markers such as CA19-9 remains ...
Di Zeng, Di Zeng, Saud Ahmad Saad, Saud Ahmad Saad, Zhen You, Zhen You, Nansheng Cheng, Nansheng Cheng   +7 more
doaj   +1 more source

Analysis of the clinical characteristics of 202 patients with liver abscess associated with diabetes mellitus and biliary tract disease

Journal of International Medical Research, 2020
Objective Clinical characteristics of patients with pyogenic liver abscess (PLA) of varying etiologies may be different. This study aimed to analyze the clinical characteristics, pathogenic bacteria, treatment, and prognosis of patients with PLA ...
Hui-Min Song, Xianbin Wang, Yubao Lian, Tuer Wan   +3 more
semanticscholar   +1 more source

Intraoral Drug Delivery: Bridging the Gap Between Academic Research and Industrial Innovations

Advanced Functional Materials, EarlyView.
Intraoral drug delivery offers a promising route for systemic and localized therapies, yet challenges such as enzymatic degradation, limited permeability, and microbial interactions hinder efficacy. This figure highlights innovative strategies—mucoadhesive materials, enzyme inhibitors, and permeation enhancers—to overcome these barriers.
Soheil Haddadzadegan, Simona Summonte, Fabrizio Ricci, Matthias Sandmeier, Andreas Bernkop‐Schnürch   +4 more
wiley   +1 more source

Diagnostics and treatment of biliary dyskinesia: clinical guidelines of the Russian gastroenterological Association

Российский журнал гастроэнтерологии, гепатологии, колопроктологии, 2018
Aim of publication. To present the guidelines on diagnostics and treatment of biliary dyskinesia to practical doctors. Summary. The gallbladder dyskinesia and sphincter of Oddi dyskinesia are defined as the diseases of functional origin caused by ...
V. T. Ivashkin, I. V. Mayev, Yu. O. Shulpekova, Ye. K. Baranskaya, A. V. Okhlobystin, A. S. Trukhmanov, T. L. Lapina, A. A. Sheptulin   +7 more
doaj   +1 more source

Colon‐Targeted Natural Polysaccharide‐Berberine Armored Hydrogel for the Treatment of Colitis

Advanced Healthcare Materials, EarlyView.
In this research, a novel hydrogel system targeting the colon is developed, incorporating Rhubarb polysaccharides and berberine‐loaded dendrimer. This hydrogel, forms through intermolecular hydrogen bonding and electrostatic interactions, accumulates in colonic tissues, effectively alleviating pathological immune hyperactivation while modulating gut ...
Miao Guo, Bo Li, Hongyi Li, Yi Chen, Qin Yuan, Mingju Shui, Hefeng Zhou, Wei Hao, Shengpeng Wang   +8 more
wiley   +1 more source

Multitasking Smart Intestinal Capsule Robot: A Cutting‐Edge Platform for Sampling, Diagnosis, and Therapy

Advanced Robotics Research, EarlyView.
Gut microbiota and biomarkers are linked to diseases like neurological disorders and metabolic syndromes. Ingestible capsule robots enable minimally invasive gut health assessment. This article proposes a promising direction for the advancement of capsule robots, integrating in situ sampling, real‐time diagnostics, and personalized therapy.
Xizong Chen, Libing Huang, Lei Ren, Miao Wang   +3 more
wiley   +1 more source

Tailoring a Functional Synthetic Microbial Community Alleviates Fusobacterium nucleatum‐infected Colorectal Cancer via Ecological Control

Advanced Science, EarlyView.
The bottom‐up strategy based on multiomics data is used for the SynCom design, and it successfully inhibited F. nucleatum growth and achieved stable colonization in vivo. In addition, it promoted tryptophan metabolism and secondary bile acid conversion, reduced lipid accumulation, relieved microbiome disorder, decreased inflammatory reaction, and ...
Zhongkun Zhou, Mengyue Yang, Hong Fang, Baizhuo Zhang, Yunhao Ma, Yongyuan Li, Yingjie Liu, Zeying Cheng, Yuanchun Zhao, Zhenzhen Si, Hongmei Zhu, Peng Chen   +11 more
wiley   +1 more source

European guidelines from the EHTG and ESCP for Lynch syndrome: an updated third edition of the Mallorca guidelines based on gene and gender

BJS (British Journal of Surgery), EarlyView., 2020
Recommendations for clinical and molecular identification of LS, surgical and endoscopic management of LS‐associated colorectal cancer and preventive measures for cancer were produced. The emphasis was on surgical and gastroenterological aspects of the cancer spectrum.
T. T. Seppälä, A. Latchford, I. Negoi, A. Sampaio Soares, R. Jimenez‐Rodriguez, L. Sánchez‐Guillén, D. G. Evans, N. Ryan, E. J. Crosbie, M. Dominguez‐Valentin, J. Burn, M. Kloor, M. von Knebel Doeberitz, F. J. B. van Duijnhoven, P. Quirke, J. R. Sampson, P. Møller, G. Möslein, on behalf of the European Hereditary Tumour Group (EHTG) and European Society of Coloproctology (ESCP)   +18 more
wiley   +1 more source

The utilisation of biliary organoids for biomedical applications

Frontiers in Bioengineering and Biotechnology
Biliary duct injury, biliary atresia (BA), biliary tract tumors, primary sclerosing cholangitis (PSC), and other diseases are commonly encountered in clinical practice within the digestive system.
Zhongwen Lei, Yijun Yang, Yang Xiang, Yang Xiang   +3 more
doaj   +1 more source