Results 81 to 90 of about 342,962 (342)

Orally Administered Functional Polyphenol‐Nanozyme‐Armored Probiotics for Enhanced Amelioration of Intestinal Inflammation and Microbiota Dysbiosis

Advanced Science, EarlyView.
This study presents a novel polyphenol‐nanozyme‐armored probiotic system (ECA@EcN) for enhanced treatment of inflammatory bowel disease (IBD). By integrating chitosan‐modified epigallocatechin gallate (EGCG‐CS) with gold nanozymes, the system effectively scavenges ROS, improves probiotic viability, and restores gut microbiota balance.
Yong Zhu, Ziqu Fang, Jie Bai, Longhui Wang, Jiaqing Chen, Zehua Zhang, Qiang Wang, Weiwei Sheng, Xueyin Pan, Zhenyuan Gao, Dengqiu Xu, Pengkai Wu, Beicheng Sun   +12 more
wiley   +1 more source

Analysis of the Serum Bile Acid Composition for Differential Diagnosis in Patients with Liver Disease

Gastroenterology Research and Practice, 2015
Objectives. We determined the serum bile acid (BA) composition in patients with liver diseases and healthy volunteers to investigate the relationship between the etiologies of liver disease and BA metabolism. Material and Methods.
Tomonori Sugita, Katsushi Amano, Masanori Nakano, Noriko Masubuchi, Masahiro Sugihara, Tomokazu Matsuura   +5 more
doaj   +1 more source

Clinical Course and Morphological Features of Chronic Gastritis in Patients with the Most Common Gastroenterological Pathology

Gastroenterologìa, 2014
The article deals with the features of clinical course and morphological state of gastric mucosa in patients with the most common gastroenterological diseases, namely: gallbladder and biliary tract diseases, non-alcoholic fatty liver disease, functional ...
A.S. Svintsytskyi, H.A. Soloviova, O.H. Kuryk, N.Ye. Dolhaia, I.V. Korendovych   +4 more
doaj   +1 more source

A Spatially Discrete Approximation to Log-Gaussian Cox Processes for Modelling Aggregated Disease Count Data [PDF]

, 2019
In this paper, we develop a computationally efficient discrete approximation to log-Gaussian Cox process (LGCP) models for the analysis of spatially aggregated disease count data. Our approach overcomes an inherent limitation of spatial models based on Markov structures, namely that each such model is tied to a specific partition of the study area, and
arxiv   +1 more source

Histone Deacetylase 6 (HDAC6) in Ciliopathies: Emerging Insights and Therapeutic Implications

Advanced Science, EarlyView.
HDAC6 regulates primary cilia, crucial for cellular signalling and environmental responses. Dysregulation of HDAC6 contributes to ciliopathies, affecting multiple organs. This review examines HDAC6's role in ciliogenesis, its interaction with signaling molecules, and its potential as a therapeutic target.
Zhiyi Wang, Xiaofan Zhu, Zhenzhou Huang, Kaidi Ren, Jie Ran, Yang Yang   +5 more
wiley   +1 more source

Diagnostic pitfalls and the value of fluorescence in situ hybridization as an adjunct to cytologic evaluation of bile duct brushings in patients with primary sclerosing cholangitis

Diagnostic Cytopathology, Volume 51, Issue 2, Page 117-122, February 2023., 2023
Abstract Background Primary sclerosing cholangitis (PSC) can present diagnostic difficulties on bile duct brushings as cytologic features mimicking adenocarcinoma may exist. This study evaluates the role of fluorescence in‐situ hybridization (FISH) as an adjunct to cytologic evaluation.
Suzanne M. Selvaggi
wiley   +1 more source

LOXL1 exerts oncogenesis and stimulates angiogenesis through the LOXL1-FBLN5/αvβ3 integrin/FAK-MAPK axis in ICC

Molecular Therapy: Nucleic Acids, 2021
Aberrant expression of lysyl oxidase-like 1 (LOXL1) reportedly leads to fibrous diseases. Recent studies have revealed its role in cancers. In this study, we observed an elevated level of LOXL1 in the tissues and sera of patients with intrahepatic ...
Ruiyan Yuan, Yang Li, Bo Yang, Zhaohui Jin, Jiacheng Xu, Ziyu Shao, Huijie Miao, Tai Ren, Yang Yang, Guoqiang Li, Xiaoling Song, Yunping Hu, Xu’an Wang, Ying Huang, Yingbin Liu   +14 more
doaj  

Issues of therapy for biliary pathology in children: the choice of the optimal solution

Zdorovʹe Rebenka, 2018
Background. Diseases of the hepatobiliary system are one of the most important problems of pediatric gastroentero­logy. Lesions of the biliary tract are associated with persistent changes in lipid metabolism that contributes to the prolonged cholestasis ...
O.V. Shutova, N.V. Pavlenko, O.N. Babadganyan, I.G. Solodovnichenko, O.V. Buksha   +4 more
doaj   +1 more source

The role of diet and nutrition related indicators in biliary diseases: an umbrella review of systematic review and meta-analysis

Nutrition & Metabolism, 2022
Background Diet and nutrition, as a modifiable risk factor, have been demonstrated to play a significant role in the etiology of biliary diseases, whereas few comprehensive studies have been able to evaluate the strength and quality of these evidence ...
Yaoqun Wang, Jiong Lu, Ningyuan Wen, Guilin Nie, Dingzhong Peng, Xianze Xiong, Nansheng Cheng, Bei Li   +7 more
doaj   +1 more source

A CNN-Based Blind Denoising Method for Endoscopic Images [PDF]

, 2020
The quality of images captured by wireless capsule endoscopy (WCE) is key for doctors to diagnose diseases of gastrointestinal (GI) tract. However, there exist many low-quality endoscopic images due to the limited illumination and complex environment in GI tract. After an enhancement process, the severe noise become an unacceptable problem.
arxiv   +1 more source