Results 191 to 200 of about 23,053 (268)

Novel therapeutic targets for chronic visceral pain in gastrointestinal disorders

open access: yesBritish Journal of Pharmacology, EarlyView.
Chronic visceral pain imposes a major clinical challenge in gastroenterology and beyond, profoundly impacting patients' quality of life. However, limited understanding of its complex, multifaceted pathophysiology, encompassing both peripheral and central mechanisms, continues to impede the development of effective management strategies.
Fleur Veldman   +3 more
wiley   +1 more source

Organ‐Specific Cancer‐Associated Fibroblast Subtypes Across the Digestive System Linked to Cancer Hallmarks

open access: yesCancer Science, EarlyView.
We integrated 14 single‐cell RNA‐seq datasets and 18 bulk cohorts to define eight CAF subtypes in GI cancers. myCAF1 and myCAF2 promoted immunosuppressive, poor‐prognosis niches, whereas iCAF1 was linked to favorable prognosis and antitumor immunity.
Huaitao Wang   +7 more
wiley   +1 more source

Single Cell Multi‐Omics Revealing the Important Role of MR1 Mediated MAIT Cells in Maintaining Rejection for Liver Transplantation

open access: yesCell Proliferation, EarlyView.
This multi‐omics study reveals the significant role of MAIT cells in liver transplant rejection. MAIT cells drive rejection in liver transplantation via the MR1 axis. Their absence reshapes T cell responses and clonal expansion, attenuating allograft injury.
Hailun Cai   +15 more
wiley   +1 more source

COVID‐19's Shadow: The Effect of COVID‐19 on Cytopathology Specimens Received at an Academic Laboratory in Central South Africa

open access: yesCytopathology, EarlyView.
Due to global COVID‐19‐related disruptions in healthcare delivery, cytopathology laboratories experienced a reduction in specimen volume that did not fully recover post‐COVID‐19. The findings of the study highlighted the importance of resilient diagnostic services during health crises.
Courtney T. A. Bonato   +2 more
wiley   +1 more source

Management of multicausal iatrogenic bile duct injuries with biliary fistula: Twenty-year experience in a tertiary center. [PDF]

open access: yesEndosc Int Open
Garbay V   +10 more
europepmc   +1 more source

Surgeon Regret and Shared Decision‐Making for Hepatopancreatobiliary Cancer: A Survey of Australia and New Zealand

open access: yes
ANZ Journal of Surgery, EarlyView.
Joshua G. Kovoor   +7 more
wiley   +1 more source

Duodenal stricture and portal gas accumulation secondary to ulcerative, fibronecrotising duodenitis in a foal

open access: yesEquine Veterinary Education, EarlyView.
Summary Gastroduodenal ulcer disease with secondary stricture formation of the proximal duodenum and portal gas accumulation is described in a neonatal foal. Conventional diagnostics were performed to reach a diagnosis, including gastroscopy, ultrasonography and positive contrast radiography. In addition, a post‐mortem CT was acquired with the contrast
R. F. Dash   +3 more
wiley   +1 more source

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