Results 41 to 50 of about 22,887 (235)

Cobalt Single‐Atom Nanozyme for Enhanced Intestinal Radioprotection and Tumor Radiosensitization via Bidirectional ROS Modulation

Advanced Science, EarlyView.
Orally administered, pH‐responsive Co‐SAN exerts dual functions: in the alkaline intestinal milieu, it scavenges reactive oxygen species (ROS) and suppresses the PI3K/AKT pathway and NETs formation, thus providing radioprotection; whereas in the acidic tumor microenvironment, it generates ROS and alleviates hypoxia, thereby enhancing radiosensitization.
Shengqi Yin, Junjie Li, Yishu Zou, Yang Liu, Yilin Zheng, Lu Yu, Wanying Zheng, Yajun Zou, Zehui Zhang, Tao Li, Peiqun Yin, Jianlin Zhang, Yuen Wu, Yi Ding   +13 more
wiley   +1 more source

Acute hemorrhagic cholecystitis with gallbladder rupture and massive intra-abdominal hemorrhage

Autopsy and Case Reports, 2021
Acute hemorrhagic cholecystitis is a rare, life-threatening condition that can be further complicated by perforation of the gallbladder. We describe a patient with clinical and radiologic findings of acute cholecystitis with a gallbladder rupture and ...
Zachary Pickell, Krishnan Raghavendran, Maria Westerhoff, Aaron M. Williams   +3 more
doaj  

A severe case of hemobilia and biliary fistula following an open urgent cholecystectomy

World Journal of Emergency Surgery, 2009
Background Cholecystectomy has been the treatment of choice for symptomatic gallstones, but remains the greatest source of post-operative biliary injuries.
Del monaco Pamela, Migliaccio Carla, Morelli Umberto, Farinella Eriberto, La Mura Francesco, Cattorini Lorenzo, Spizzirri Alessandro, Cirocchi Roberto, Napolitano Vincenzo, Trastulli Stefano, Di Patrizi Micol, Milani Diego, Sciannameo Francesco   +12 more
doaj   +1 more source

Comparison of spectral characteristics in human and pig biliary system with hyperspectral imaging (HSI)

Current Directions in Biomedical Engineering, 2020
Injuries to the biliary tree during surgical, endoscopic or invasive radiological diagnostic or therapeutic procedures involving the pancreas, liver or organs of the upper gastrointestinal tract give rise to the need to develop a method for clear ...
Cooney Gary Sean, Barberio Manuel, Diana Michele, Sucher Robert, Chalopin Claire, Köhler Hannes   +5 more
doaj   +1 more source

Hypothalamic Control of Liver Health and Disease: From Circuits to Pathophysiology and Therapies

Advanced Science, EarlyView.
This review delineates the hypothalamic circuits that control liver homeostasis via autonomic and neuroendocrine pathways. Dysregulation of this hypothalamus–liver axis drives disease progression across a spectrum including steatotic liver disease, liver inflammation and injury, fibrosis, cirrhosis, and hepatocellular carcinoma.
Qin Tang, Jiahui Li, Haiying Song, Ailin Zhang, Haifeng Zeng, Yining Xu, Li Mo, Jinhan He   +7 more
wiley   +1 more source

AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury

, 2022
Hepatology, EarlyView.
Robert J. Fontana, Iris Liou, Adrian Reuben, Ayako Suzuki, M. Isabel Fiel, William Lee, Victor Navarro   +6 more
wiley   +1 more source

Biodegradable Stents: A Breakthrough in the Management of Complex Biliary Tract Injuries: A Case Report

Reports
Background and Clinical Significance: Biliary tract injuries are a recognized complication of laparoscopic cholecystectomy. Early diagnosis and prompt management are crucial to minimize complications such as bile leaks, strictures, and fistula formation.
Ottavia Cicerone, Giulio Di Gioia, Maria Pajola, Anna Gallotti, Antonio Mauro D’Agostino, Nicola Cionfoli, Riccardo Corti, Pietro Quaretti, Marcello Maestri   +8 more
doaj   +1 more source

Targeting Tex10 Overcomes Oxaliplatin Resistance by Competitively Disrupting the Non‐Canonical BAF Complex in Colorectal Cancer

Advanced Science, EarlyView.
This study reveals that Tex10 drives oxaliplatin resistance in colorectal cancer by competitively binding BRD9 to disrupt the ncBAF complex, thereby suppressing AMBRA1 transcription and ULK1‐mediated autophagy. Gemcitabine is identified as a direct Tex10 inhibitor that restores autophagy and overcomes resistance.
Ping Xu, Jie Huang, Xiaojin Gao, Lin Deng, Yanheng Deng, Denglu Wang, Chunlei Yu, Yunxiang Zhang, Jingdong Li, Xiaocong Xiang   +9 more
wiley   +1 more source

Heat Stress and Gut Microbiome Dynamics in Poultry: Interplay, Consequences, and Mitigation Strategies

Animal Research and One Health, EarlyView.
Heat stress disrupts gut microbial balance in poultry, impairing nutrient absorption and immunity. This review outlines the interplay between thermal stress and microbiome dynamics and discusses integrative mitigation strategies, probiotics, phytogenics, cooling systems, and genetic adaptation to enhance poultry resilience.
O. E. Oke, A. I. Oni, O. A. Akosile, K. M. Oliyide, C. A. Ishola, M. O. Logunleko, O. A. Jimoh, C. P. Njoku, L. O. Fasasi, V. A. Uyanga   +9 more
wiley   +1 more source

Frequency of Rouviere's Sulcus and its Relation to the Dissection Time of Calot's Triangle

Journal of the Dow University of Health Sciences
Objective: To determine the frequency of Rouviere's Sulcus in patients undergoing laparoscopic cholecystectomy and assess its relationship with the dissection time of Calot's Triangle.
Faryal Sajid, Tariq Mukhtar Farani, Muhammad Waqas Ahmed Bhati, Mubashir Ahmad Toor, Fatima Farooq   +4 more
doaj   +2 more sources