Abstract Hypoxic‐ischemic encephalopathy (HIE) resulting from perinatal asphyxia presents a substantial risk of mortality and long‐term sequelae in neonates. Therapeutic hypothermia (TH) improves both short‐ and long‐term outcomes in near‐term/term neonates with moderate to severe HIE.
Zoë Vander Elst+10 more
wiley +1 more source
Feasibility study of texture-based machine learning approach for early detection of neonatal jaundice. [PDF]
Phattraprayoon N+5 more
europepmc +1 more source
Abstract Fenofibrate is contraindicated in patients with advanced hepatic fibrosis due to limited clinical data. We evaluated the pharmacokinetics and safety of fenofibrate in participants with mild hepatic impairment (phase 1 study) or advanced fibrosis due to metabolic‐associated fatty liver disease (MAFLD; phase 2a study).
Islam R. Younis+5 more
wiley +1 more source
Bilirubin Metabolism Does Not Influence Serum Bile Acid Profiles According to LC-MS: A Human Case-Control Study. [PDF]
Stelzer TC+8 more
europepmc +1 more source
Effects of Hepatic or Renal Impairment on Pharmacokinetics of Fruquintinib
Abstract Fruquintinib (FRUZAQLATM) is a highly selective tyrosine kinase inhibitor of all three vascular endothelial growth factor receptors (‐1, ‐2, and ‐3). Two Phase 1, open‐label, single‐dose studies investigated the impact of hepatic or renal impairment on the pharmacokinetics and tolerability of fruquintinib.
Martha Gonzalez+8 more
wiley +1 more source
Rapid Resolution of Anabolic Androgenic Steroid-Induced Refractory Pruritus and Bile Cast Nephropathy With Therapeutic Plasma Exchange. [PDF]
Wong S, Con D, Majumdar A.
europepmc +1 more source
Drug‐induced liver injury associated with exposure to Hangeshashinto
While Kampo medicines are deemed relatively safe and associated with few adverse effects, primary care physicians are well advised to be aware of the risk of drug‐induced liver injury in patients prescribed Kampo medicines containing Scutellariae radix, such as Hangeshashinto, in clinical practice and to closely monitor their clinical course.
Kimitoshi Kubo+2 more
wiley +1 more source
Transjugular Liver Biopsy for Histological Diagnosis of Refractory Ascites and Evaluation of Portal Hypertension. [PDF]
Ishikawa T+8 more
europepmc +1 more source
Association between serum total bilirubin levels and 28-day all-cause mortality after intracerebral hemorrhage. [PDF]
Qiu D, Li G, Dong Y.
europepmc +1 more source
Biochemical, coagulation, and platelet count profiles among Schistosoma mansoni infected patients attending at selected Dembiya health institutions, Northwest Ethiopia. [PDF]
Abebe W+10 more
europepmc +1 more source