Results 51 to 60 of about 37,436 (239)

Microenvironment‐Responsive Nanomedicine Enables Vertical Modulation of Mitochondrial Pathological Networks in Myocardial Ischemia–Reperfusion Injury

open access: yesAdvanced Science, EarlyView.
A mitochondria‐targeted, microenvironment‐responsive nanoplatform enables pH/ROS‐triggered co‐delivery of berberine and isoliensinine to orchestrate ROS scavenging, inflammation suppression, and apoptosis inhibition. This vertical modulation of mitochondrial pathological networks preserves mitochondrial function and effectively mitigates myocardial ...
Jue Wang   +11 more
wiley   +1 more source

Comparison of Single-Camera-Based Depth Estimation Technology for Digital Twin Model Synchronization of Underground Utility Tunnels

open access: yesApplied Sciences, 2023
Digital twin technology can be used for disaster safety management of underground utility tunnels, which are social infrastructures. To verify its efficiency in an underground utility tunnel, it must be implemented and monitored in the real world ...
Sangmi Park   +3 more
doaj   +1 more source

Cancer‐Associated BCL‐2 Mutants Reveal Mechanisms Towards Venetoclax Resistance

open access: yesAdvanced Science, EarlyView.
Venetoclax (VEN) resistance in chronic lymphocytic leukemia arises from diverse BCL2 mutations. We map mechanisms contributing to VEN resistance across common BCL‐2 variants. G101V and D103Y reduce drug binding and increase sequestration of pro‐apoptotic proteins. V156D blocks VEN allosterically.
Jonas Aufdermauer   +9 more
wiley   +1 more source

BIM coordinators: a review

open access: yesEngineering, Construction and Architectural Management, 2018
Purpose The purpose of this paper is to explore the role, practices and responsibilities of building information modeling (BIM) coordinators (BCs). Design/methodology/approach The aim is achieved through a review of existing publications (n=183) in which the term “BIM coordinators” has been described and discussed (n=78), complemented by interviews ...
Jacobsson, Mattias   +1 more
openaire   +3 more sources

People’s perspectives on heritage conservation and tourism development: a case study of Varanasi

open access: yesBuilt Heritage, 2023
The conservation of heritage and heritage-based tourism are interrelated activities in which the development in one can lead to the growth of the other and vice versa.
Ananya Pati, Mujahid Husain
doaj   +1 more source

How to Navigate Disrupted Business Models in the 21st Century: At the Crossroads of the Circular Economy and the Industry 4.0 Transition

open access: yesBusiness Strategy and the Environment, EarlyView.
ABSTRACT Our planet faces a critical crisis, with pollution, resource depletion and biodiversity loss surpassing sustainable limits. Businesses must address these challenges, with the circular economy and Industry 4.0 offering transformative potential through closed‐loop systems, regenerative solutions and advanced technologies.
Agnes Toth‐Peter   +3 more
wiley   +1 more source

Undoing one-dimensionality: reforming German citizenship through the postmigrant framework

open access: yesComparative Migration Studies
This paper critically examines Germany’s 2024 citizenship reform, designed to promote integration and pluralism through legal and societal transformations. We argue that the prevailing migration discourse in Germany reinforces a one-dimensional political
Tunay Altay   +2 more
doaj   +1 more source

Trapped in the NETs: Multiple Roles of Platelets in the Vascular Complications Associated with Neutrophil Extracellular Traps

open access: yesCells
Neutrophil extracellular traps (NETs) have received significant attention in recent years for their role in both the immune response and the vascular damage associated with inflammation.
Christopher Sennett, Giordano Pula
doaj   +1 more source

Internal Mission by St Nicholas the Wonderworker Brotherhood in Vyatka in the late XIX and early XX Century [PDF]

open access: yesВестник Свято-Филаретовского института, 2015
The article reviews and analyses the missionary and educational work carried out by St Nicholas the Wonderworker Brotherhood in Vyatka, founded by Archpriest Stefan Kashmensky in 1882. The Brotherhood was engaged in educating the Old Believers population
Ekaterina Bim
doaj  

A Decision‐Making Model for Implementing Green Technology in Sustainable Building Projects

open access: yesBusiness Strategy and the Environment, EarlyView.
ABSTRACT Green technology (GT) adoption is pivotal for reconciling environmental stewardship with economic viability in the built environment, particularly in resource‐constrained emerging economies. However, empirical evidence on how specific GT drivers actively mitigate adoption barriers remains scarce.
Abdelazim Ibrahim   +5 more
wiley   +1 more source

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