Results 101 to 110 of about 329,503 (293)
Advanced Science, EarlyView.TRMT6‐mediated m1A modification in CDK9 mRNA enhances its mRNA stability and translation efficiency, thereby increasing the protein levels of CDK9. Upregulated CDK9 promotes the progression of HCC by elevating the levels of oncogenic factors including p‐STAT3, MCL1, and BCL‐2. On the other hand, CDK9 phosphorylates TARDBP at Ser254 to activate HBV core
Rui Zhang +12 more
wiley +1 more source
Short Gamma Ray Bursts: a bimodal origin?
, 2008 Short-hard Gamma Ray Bursts (SGRBs) are currently thought to arise from gravitational wave driven coalescences of double neutron star systems forming either in the field or dynamically in globular clusters.
A. Cerutti +54 more
core +1 more source
Brazilian Bimodal Bilinguals as Heritage Signers
Languages, 2018 This paper presents an analysis of heritage signers: bimodal bilinguals, who are adult hearing children of Deaf parents who acquired sign language at home with their parents and the spoken language from the surrounding community.
Ronice Müller de Quadros +1 more
doaj +1 more source
De Novo Multi‐Mechanism Antimicrobial Peptide Design via Multimodal Deep Learning
Advanced Science, EarlyView.Current AI‐driven peptide discovery often overlooks complex structural data. This study presents M3‐CAD, a generative pipeline that leverages 3D voxel coloring and a massive database of over 12 000 peptides to capture nuanced physicochemical contexts.
Xiaojuan Li +23 more
wiley +1 more source
The Ising Spin Glass in dimension four
, 2015 The critical behaviors of the bimodal and Gaussian Ising spin glass (ISG) models in dimension four are studied through extensive numerical simulations, and from an analysis of high temperature series expansion (HTSE) data of Klein {\it et al.} (1991 ...
Campbell, I. A., Lundow, P. H.
core +3 more sources
Causal Prediction of TP53 Variant Pathogenicity Using a Perturbation‐Informed Protein Language Model
Advanced Science, EarlyView.A TP53‐specific predictor, CaVepP53, is developed by fine‐tuning ESMC on experimentally validated variants, quantifying pathogenicity via Euclidean distances. It outperforms general‐purpose models and extends to five cancer genes, enabling interpretable variant classification for precision medicine.
Huiying Chen +15 more
wiley +1 more source
Development of multisensory spatial integration and perception in humans [PDF]
, 2006 Previous studies have shown that adults respond faster and more reliably to bimodal compared to unimodal localization cues. The current study investigated for the first time the development of audiovisual (A‐V) integration in spatial localization ...
Chee-Ruiter, Christine +4 more
core
Is bimodality a sufficient condition for a first order phase transition existence?
, 2013 Here we present two explicit counterexamples to the widely spread beliefs about an exclusive role of bimodality as the first order phase transition signal.
Bugaev, K. A. +3 more
core +1 more source
Advanced Science, EarlyView.Ru–Mn composite nanozymes are engineered to mimic dual‐enzyme cascade catalysis, enabling efficient ROS clearance and neuroinflammation suppression. In collagenase‐ and autologous blood‐induced ICH mouse models, intranasal and intravenous administration reduced hematoma volume, preserved BBB integrity, and improved neurological recovery.
Zhongxin Duan +8 more
wiley +1 more source
The surprising external upturn of the Blue Straggler radial distribution in M55
, 2007 By combining high-resolution HST and wide-field ground based observations, in ultraviolet and optical bands, we study the Blue Straggler Star (BSS) population of the low density galactic globular cluster M55 (NGC 6809) over its entire radial extent.
A. Sollima +12 more
core +1 more source