Results 141 to 150 of about 11,612 (265)

SHAP-based binarization enhances metataxonomic machine learning with application to gut microbiota of inflammatory bowel disease. [PDF]

Sci Rep
Lee Y, Seo J, Di Camillo B.
europepmc   +1 more source

Model‐Based Analysis with Mechanistic Insights to CAR‐T‐Cell Therapy Kinetics: Case Study with Axicabtagene Ciloleucel and Brexucabtagene Autoleucel

Clinical Pharmacology &Therapeutics, EarlyView.
Model‐informed drug development is increasingly used to support chimeric antigen receptor (CAR)‐T‐cell therapy programs. However, most population pharmacokinetic (PK) CAR‐T‐cell models available in literature are variations of an empirical piecewise‐linear model, which accurately describes the observed data but lacks a mechanistic foundation.
Anna M. Mc Laughlin, Martin Bergstrand, Ana Ruiz‐Garcia, Simone Filosto, Rhine Shen   +4 more
wiley   +1 more source

New Binary Reptile Search Algorithms for Binary Optimization Problems. [PDF]

Biomimetics (Basel)
Crawford B, López Cortés B, Cisternas-Caneo F, Gómez-Pulido JM, Olivares R, Soto R, Barrera-Garcia J, Brante-Aguilera C, Giachetti G.   +8 more
europepmc   +1 more source

Acoustic‐driven surface cleaning with millimeter‐sized bubbles at translational resonance

Droplet, EarlyView.
Time‐lapse visualization comparing bubble trajectories. The top panel (0 Hz) shows a bubble's linear path under no acoustic forcing, while the bottom panel (50 Hz) demonstrates the oscillatory motion induced by acoustic waves at a resonance mode. This mechanism holds promising potential for applications such as surface cleaning.
Yan Jun Lin, Zhengyang Liu, Sunghwan Jung   +2 more
wiley   +1 more source

Compression-Efficient Feature Extraction Method for a CMOS Image Sensor. [PDF]

Sensors (Basel)
Kuroda K, Osuka Y, Iegaki R, Ujiie R, Shima H, Yoshida K, Okura S.   +6 more
europepmc   +1 more source

Exponentially‐constrained Gaussian mixture model for quantifying vertical development of water‐conducting fracture zones in lithologically stratified mining roofs

Deep Underground Science and Engineering, EarlyView.
This study proposes an exponentially‐constrained Gaussian mixture model (EcGMM) to quantify vertical fracture heterogeneity in stratified roof strata. The model integrates a piecewise exponential decay term capturing global stress dissipation with Gaussian components representing localized fracture intensification at lithological interfaces.
Huiqing Yuan, Zhimin Xu, Weixiao Chen, Chenghang Zhang, Shijie Xiong, Yajun Sun   +5 more
wiley   +1 more source

Binary Pufferfish Optimization Algorithm for Combinatorial Problems. [PDF]

Biomimetics (Basel)
Crawford B, Paz Á, Soto R, Peña Fritz Á, Astorga G, Cisternas-Caneo F, Toledo Mac-Lean CP, Solís-Piñones F, Arce JL, Giachetti G.   +9 more
europepmc   +1 more source

‘biomod2' – extending presence–absence species distribution models to multiple data types

Ecography, EarlyView.
The R package ‘biomod2' is one of the most widely used and versatile tools for species distribution modelling (SDM), enabling ecologists to calibrate, evaluate, and project species–environment relationships across space and time using multiple modelling algorithms and ensemble forecasting.
Maya Guéguen, Hélène Blancheteau, Rémi Lemaire‐Patin, Wilfried Thuiller   +3 more
wiley   +1 more source

A Dual-Role Amphiphilic Photosensitizer: Enhancing Structural Uniformity and Optical Properties of Langmuir Monolayers. [PDF]

Langmuir
Finkelmeyer SJ, Mankel C, Elmanova A, Hotzel K, Ye Z, Dellith A, Zechel S, Peneva K, Hager MD, Schubert US, Presselt M.   +10 more
europepmc   +1 more source

CardiLect: A combined cross‐species lectin histochemistry protocol for the automated analysis of cardiac remodelling

ESC Heart Failure, Volume 12, Issue 2, Page 1398-1415, April 2025.
Abstract Background Cardiac remodelling, a crucial aspect of heart failure, is commonly investigated in preclinical models by quantifying cardiomyocyte cross‐sectional area (CSA) and microvascular density (MVD) via histological methods, such as immunohistochemistry.
Tamás G. Gergely, Tamás Kovács, Andrea Kovács, Viktória E. Tóth, Nabil V. Sayour, Gábor M. Mórotz, Csenger Kovácsházi, Gábor B. Brenner, Zsófia Onódi, Balázs Enyedi, Domokos Máthé, Przemyslaw Leszek, Zoltán Giricz, Péter Ferdinandy, Zoltán V. Varga   +14 more
wiley   +1 more source