Cryo‐EM structure of ALC1 in an open conformation bound to a PARylated nucleosome
Reanalysis of a publicly available cryo‐EM dataset identifies a new conformation of the oncogenic chromatin remodeler ALC1/CHD1L bound to a PARylated nucleosome. This new structure reveals the position of the macro domain in the complex, and may help to understand the large conformational change leading to the activation of ALC1.Nucleosomes are the ...
Hannah R. Bridges +3 more
wiley +1 more source
Risk identification strategies for health pandemics and epidemics on college campuses: A comprehensive analysis of heat maps and behavioral observations. [PDF]
Laske MM +4 more
europepmc +1 more source
Bee community assembly is regulated by functional traits in pristine tropical forest environments
Read the free Plain Language Summary for this article on the Journal blog. Abstract Understanding the drivers of bee beta diversity across pristine environments in the Amazon is critical for ensuring biodiversity conservation, restoration, sustainable land use planning and economic development.
Rafael Cabral Borges +7 more
wiley +1 more source
Historical Manuscripts Analysis: A Deep Learning System for Writer Identification Using Intelligent Feature Selection with Vision Transformers. [PDF]
Boudraa M +4 more
europepmc +1 more source
This graphical abstract illustrates the impacts of climate change on the distribution of the Amazon‐endemic canid Atelocynus microtis, highlighting projected habitat loss under future scenarios (SSP2–4.5 and SSP5–8.5). Despite substantial reductions in suitable habitat, a significant proportion remains within Protected Areas, emphasizing their critical
Isabella Soares Moura Palha da Silva +3 more
wiley +1 more source
Analysing complex excitation patterns in cardiac tissue using wave event networks. [PDF]
Von Koeller HF +5 more
europepmc +1 more source
A tutorial on Bayesian model averaging for exponential random graph models
Abstract The use of exponential random graph models (ERGMs) is becoming prevalent in psychology due to their ability to explain and predict the formation of edges between vertices in a network. Valid inference with ERGMs requires correctly specifying endogenous and exogenous effects as network statistics, guided by theory, to represent the network ...
Ihnwhi Heo +2 more
wiley +1 more source
In Situ Quantization with Memory-Transistor Transfer Unit Based on Electrochemical Random-Access Memory for Edge Applications. [PDF]
Yang Z +9 more
europepmc +1 more source
LLM‐based prior elicitation for Bayesian graphical modeling
ABSTRACT In the Bayesian graphical modeling framework, priors on network structure encode theoretical assumptions and uncertainty about the topology of psychological constructs under study. For instance, the Bernoulli prior specifies the probability of each pairwise interaction, the Beta–Bernoulli prior governs expected network density, and the ...
Nikola Sekulovski +2 more
wiley +1 more source
Automated Analysis of the Foveal Avascular Zone in Optical Coherence Tomography Angiography Before and After Phacoemulsification. [PDF]
Pighin MS +3 more
europepmc +1 more source

