Results 201 to 210 of about 33,048 (289)

Human Colitis‐on‐Chip Model Reveals Dual Roles of Butyrate in Epithelial and Macrophage Defense Against Candida albicans Tissue Invasion

open access: yesSmall, EarlyView.
This study establishes a human immunocompetent colitis‐on‐chip model that mimics inflamed gut mucosa and enables quantitative analysis of Candida albicans tissue invasion under DSS‐induced injury. It reveals that microbiota‐derived butyrate simultaneously stabilizes epithelial junctions and reprograms macrophages via HDAC/NLRP3‐dependent mechanisms ...
Manuel Allwang   +16 more
wiley   +1 more source

Retinal Vasculature in Schizophrenia Spectrum Disorder. [PDF]

open access: yesBioengineering (Basel)
Sherman CS   +9 more
europepmc   +1 more source

In Vitro Reconstruction of Axonal Heat Sensing with a Photothermal Nerve‐on‐a‐Chip

open access: yesSmall, EarlyView.
A photothermal nerve‐on‐a‐chip platform is presented that enables precise, localized heating of sensory axons with simultaneous electrical recording. The system reveals millisecond‐scale dynamics of heat‐evoked neural activity and provides a new approach to study how temperature‐dependent ion channel behavior is translated into axonal firing.
Koji Sakai   +6 more
wiley   +1 more source

Precise 3D Tracking of Highly Non‐Planar Eukaryotic Flagellar Beating Patterns Using Digital Holographic Microscopy

open access: yesSmall Methods, EarlyView.
The 3D beating dynamics of eukaryotic flagella drive motility, sensory functions, and resource acquisition, yet highly non‐planar beating patterns remain poorly characterized. Based on Digital Holographic Microscopy, holoV3C enables label‐free 3D reconstruction of such complex dynamics with 53 nm axial resolution, demonstrated on mouse sperm and ...
Patryk Nienaltowski   +7 more
wiley   +1 more source

Multispectral Quantum Dot Tags for Advanced Anticounterfeiting Applications. [PDF]

open access: yesACS Appl Nano Mater
Ali SR   +4 more
europepmc   +1 more source

Brain Pericytes and Wnt/β‐Catenin Signaling Induce Functional Blood–Brain Barrier Phenotype in Human iPSC‐Derived Model

open access: yesSmall Methods, EarlyView.
This study shows that human iPSC‐derived endothelial cells acquire a functional blood–brain barrier phenotype when co‐cultured with brain pericytes and stimulated with CHIR‐99021, a Wnt/β‐catenin activator. This model recapitulates key barrier properties, inflammatory responses, and transcriptomic features of the native human BBB, offering new ...
Henrique Nogueira Pinto   +12 more
wiley   +1 more source

Blurred magnitude homology of functional connectome for ASD diagnosis. [PDF]

open access: yesFront Psychiatry
Kachura A   +3 more
europepmc   +1 more source

Low‐Cost Ambient Pressure Drying Approach for Highly Porous Nanomaterial Structures

open access: yesSmall Methods, EarlyView.
We propose a simple, low‐cost method to dry highly porous nanomaterial structures at ambient temperature and pressure. Using low surface tension solvents, this technique minimizes capillary forces, preventing pore collapse and material shrinkage. This bypasses the need for expensive and size‐limiting critical point drying, enabling scalable production ...
Erik Greve   +5 more
wiley   +1 more source

Concrete Crack Detection and Classification Methods Based on Machine Vision and Deep Learning. [PDF]

open access: yesSensors (Basel)
Chen W   +7 more
europepmc   +1 more source

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