Results 71 to 80 of about 3,684,944 (327)

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

The TESS Ten Thousand Catalog: 10,001 Uniformly Vetted and Validated Eclipsing Binary Stars Detected in Full-frame Image Data by Machine Learning and Analyzed by Citizen Scientists

The Astrophysical Journal Supplement Series
The Transiting Exoplanet Survey Satellite (TESS) has surveyed nearly the entire sky in full-frame image mode with a time resolution of 200 s to 30 minutes and a temporal baseline of at least 27 days.
Veselin B. Kostov, Brian P. Powell, Aline U. Fornear, Marco Z. Di Fraia, Robert Gagliano, Thomas L. Jacobs, Julien S. de Lambilly, Hugo A. Durantini Luca, Steven R. Majewski, Mark Omohundro, Jerome Orosz, Saul A. Rappaport, Ryan Salik, Donald Short, William Welsh, Svetoslav Alexandrov, Cledison Marcos da Silva, Erika Dunning, Gerd Gühne, Marc Huten, Michiharu Hyogo, Davide Iannone, Sam Lee, Christian Magliano, Manya Sharma, Allan Tarr, John Yablonsky, Sovan Acharya, Fred Adams, Thomas Barclay, Benjamin T. Montet, Susan Mullally, Greg Olmschenk, Andrej Prša, Elisa Quintana, Robert Wilson, Hasret Balcioglu, Ethan Kruse, The Eclipsing Binary Patrol Collaboration   +38 more
doaj   +1 more source

The evolution of a supermassive binary caused by an accretion disc

, 1998
The interaction of a massive binary and a non-self-gravitating circumbinary accretion disc is considered. The shape of the stationary twisted disc produced by the binary is calculated.
A. G. Polnarev, Artymowicz, Artymowicz, Artymowicz, Bahcall, Begelman, Demianski, Goldreich, Illarionov, Ivanov, Ivanov, J. C. B. Papaloizou, Jensen, Jensen, Kumar, Kumar, Kumar, Lehto, Lightman, Lin, Lin, Lin, Lyubarskii, P. B. Ivanov, Papaloizou, Papaloizou, Papaloizou, Peters, Petterson, Polnarev, Pringle, Quinlan, Quinlan, Rees, Scheuer, Shakura, Spitzer, Syer, Vokrouhlicky, Ward, Young   +40 more
core   +2 more sources

Binary Domain Generalization for Sparsifying Binary Neural Networks

, 2023
Accepted as conference paper at ECML PKDD ...
Riccardo Schiavone, Francesco Galati, Maria A. Zuluaga   +2 more
openaire   +3 more sources

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

IMNM: integrated multi-network model for identifying pepper leaf diseases

Frontiers in Plant Science
As a vegetable crop with high economic value, the yield of pepper is often significantly restricted by leaf diseases, and the spots formed by these diseases on the surface of leaves are highly complex in color and texture characteristics. To overcome the
Zhaopeng Cai, Zhaopeng Cai, Nadia Farhana, Asif Mahbub Karim, Fengyan Zhai, Wenwen Huang, Meng Guo   +6 more
doaj   +1 more source

Formation of ultra-compact X-ray binaries through circum-binary disk-driven mass transfer

, 2009
The formation of ultra-compact X-ray binaries (UCXBs) has not been well understood. Previous works show that ultra-short orbital periods ($
Andronov, Belczynski, Belle, Bildsten, Bo Ma, Brinkworth, Chakrabarty, Chen, Chou, Deloye, Deloye, Dieball, Dubus, Dubus, Eggleton, Eggleton, Gallo, Galloway, Han, Heinke, Heinke, Hoard, Howell, Ireland, Ivanova, Juett, Kim, King, Krauss, Krimm, Krishnamurthi, Landau, Lombardi, Ma, Markwardt, Monnier, Muno, Nelemans, Nelson, Paltrinieri, Piro, Podsiadlowski, Pols, Pylyser, Queloz, Rasio, Savonije, Shakura, Shaposhnikov, Sills, Spruit, Taam, Tutukov, van den Heuvel, van der Klis, van der Klis, Verbunt, Wang, Wijnands, Willems, Winters, Xiang-Dong Li   +61 more
core   +1 more source

Binary Population and Spectral Synthesis Version 2.1: Construction, Observational Verification, and New Results [PDF]

Publications Astronomical Society of Australia, 2017
The Binary Population and Spectral Synthesis suite of binary stellar evolution models and synthetic stellar populations provides a framework for the physically motivated analysis of both the integrated light from distant stellar populations and the ...
J. Eldridge, E. Stanway, L. Xiao, L. McClelland, G. Taylor, M. Ng, S. Greis, J. Auckland, Nz, U. Warwick, UK.   +10 more
semanticscholar   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

Molecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute, Júlia Huguet‐Pradell, Jordi Abril‐Fornaguera, Albert Gris‐Oliver, Alex Rialdi, Elisa Fernández‐Martínez, Carla Montironi, Vanessa Del Pozo, Peter Houghton, Laura Zanatto, Agavni Mesropian, Ieva Keraite, Swan Thung, Carolina Armengol, Pau Sancho‐Bru, Ernesto Guccione, Roser Pinyol, Josep M. Llovet   +17 more
wiley   +1 more source

A m-ary linear feedback shift register with binary logic [PDF]

, 1973
A family of m-ary linear feedback shift registers with binary logic is disclosed. Each m-ary linear feedback shift register with binary logic generates a binary representation of a nonbinary recurring sequence, producible with a m-ary linear feedback ...
Perlman, M.
core   +1 more source