Results 41 to 50 of about 2,170,347 (337)

Relation of Adverse Childhood Experiences to Clinical and Patient‐Reported Outcomes for Adults With Sickle Cell Disease: A Registry Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Adverse childhood experiences (ACEs) are stressful or traumatic events prior to age 18 that are known to have a lasting impact on individuals’ health and well‐being. There is a gap in understanding the relationship between ACEs and Other Life Stressors and health status for adults with sickle cell disease (SCD).
Marsha Treadwell   +8 more
wiley   +1 more source

Close binary systems among very low mass stars and brown dwarfs

open access: yes, 2005
Using Monte Carlo simulations and published radial velocity surveys we have constrained the frequency and separation (a) distribution of very low mass star (VLM) and brown dwarf (BD) binary systems. We find that simple Gaussian extensions of the observed
Bate   +21 more
core   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser   +14 more
wiley   +1 more source

Binary sequence detector uses minimum number of decision elements [PDF]

open access: yes, 1966
Detector of an n bit binary sequence code within a serial binary data system assigns states to memory elements of a code sequence detector by employing the same order of states for the sequence detector as that of the sequence generator when the linear ...
Perlman, M.
core   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

A binary deletion channel with a fixed number of deletions

open access: yes, 2013
Suppose a binary string x = x_1...x_n is being broadcast repeatedly over a faulty communication channel.
Graham, Benjamin
core   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Binary Differential Evolution with a Limited Maximum Number of Dimension Changes

open access: yesAlgorithms
Evolutionary Algorithms (EAs) are those based on the phenomenon of survival of the fittest. Differential Evolution (DE) is a member of this family, and it is well-suited for handling problems with real-valued variables. However, to use DE to solve binary
Jade Filgueira   +5 more
doaj   +1 more source

ON THE BINARY DIGITS OF ALGEBRAIC NUMBERS [PDF]

open access: yesJournal of the Australian Mathematical Society, 2010
AbstractBorel conjectured that all algebraic irrational numbers are normal in base 2. However, very little is known about this problem. We improve the lower bounds for the number of digit changes in the binary expansions of algebraic irrational numbers.
openaire   +2 more sources

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

open access: yesMolecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute   +17 more
wiley   +1 more source

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