Results 41 to 50 of about 679,825 (262)
Binary quantum random number generator based on value indefinite observables
Scientific ReportsAll quantum random number generators based on measuring value indefinite observables are at least three-dimensional because the Kochen–Specker Theorem and the Located Kochen–Specker Theorem are false in dimension two.
Cristian S. Calude, Karl Svozil
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On the Number of Subword Reconstructions in the Binary Alphabet when Superimposed on one Character
Современные информационные технологии и IT-образование, 2020 The problem of obtaining accurate estimates of the number of reconstructions for words over a binary alphabet is considered. Subwords of different lengths from a given set are joined by the method of overlapping end characters.
Galina Zhukova +2 more
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An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
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Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
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Binary Differential Evolution with a Limited Maximum Number of Dimension Changes
AlgorithmsEvolutionary Algorithms (EAs) are those based on the phenomenon of survival of the fittest. Differential Evolution (DE) is a member of this family, and it is well-suited for handling problems with real-valued variables. However, to use DE to solve binary
Jade Filgueira +5 more
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SiGMoiD: A super-statistical generative model for binary data.
PLoS Computational Biology, 2021 In modern computational biology, there is great interest in building probabilistic models to describe collections of a large number of co-varying binary variables. However, current approaches to build generative models rely on modelers' identification of
Xiaochuan Zhao +2 more
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Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
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Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
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DETERMINING THE NUMBER OF CLUSTERS FOR MARKETING BINARY DATA.
Quantitative Methods in Economics, 2015 In the article a new way of determining the number of clusters was proposed focused on data made up of binary variables. An important application aspect is that the data sets on which the new formula was investigated were generated in the way ...
Jerzy Korzeniewski
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Molecular Oncology, EarlyView.Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi +14 more
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