D-optimal Factorial Designs under Generalized Linear Models [PDF]
, 2013 Generalized linear models (GLMs) have been used widely for modelling the mean response both for discrete and continuous random variables with an emphasis on categorical response.
Mandal, Abhyuday, Yang, Jie
core
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Bits from Photons: Oversampled Image Acquisition Using Binary Poisson Statistics [PDF]
, 2011 We study a new image sensor that is reminiscent of traditional photographic film. Each pixel in the sensor has a binary response, giving only a one-bit quantized measurement of the local light intensity.
Lu, Yue M. +3 more
core +3 more sources
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Eco‐Friendly Extraction and Utilization of Agro Crop Wastes Based Natural Dye for Textile Dyeing
Energy Science & EngineeringThe incorporation of waste plant residues into practical applications, particularly as a sustainable source of green dyes in textiles, is increasingly recommended by the global community.
Nimra Amin +4 more
doaj +1 more source
Reconfigurable THz Metamaterial Filter Based on Binary Response for Information Processing System
Frontiers in Physics, 2021 Light-matter interactions between the metallic and dielectric layers along with the controlling of electromagnetic waves can create a way to develop micro-devices and moderate the functionalities for advanced applications.
Eistiak Ahamed +4 more
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Fuzzy ART: An Adaptive Resonance Algorithm for Rapid, Stable Classification of Analog Patterns [PDF]
, 1991 The Fuzzy ART system introduced herein incorporates computations from fuzzy set theory into ART 1. For example, the intersection (n) operator used in ART 1 learning is replaced by the MIN operator (A) of fuzzy set theory.
Carpetner, Gail A. +2 more
core +1 more source
Optimal Crowdsourced Classification with a Reject Option in the Presence of Spammers
, 2017 We explore the design of an effective crowdsourcing system for an $M$-ary classification task. Crowd workers complete simple binary microtasks whose results are aggregated to give the final decision.
Li, Qunwei, Varshney, Pramod K.
core +1 more source