Results 51 to 60 of about 449,237 (302)

Eco‐Friendly Extraction and Utilization of Agro Crop Wastes Based Natural Dye for Textile Dyeing

Energy Science & Engineering
The incorporation of waste plant residues into practical applications, particularly as a sustainable source of green dyes in textiles, is increasingly recommended by the global community.
Nimra Amin, Fazal‐ur‐ Rehman, Shahid Adeel, Muhammad Ibrahim, Rony Mia   +4 more
doaj   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

Molecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi, Stavros Makrodimitris, Sandra van Wilpe, Iris te Paske, Vanja de Weerd, Corine M. Beaufort, Hans M. Westgeest, Jens Voortman, Maureen J. B. Aarts, Maud Rijnders, Astrid A. M. van der Veldt, Ronald de Wit, Niven Mehra, Saskia M. Wilting, Debbie G. J. Robbrecht   +14 more
wiley   +1 more source

Bin-3-Way-PARAFAC-PLS: A 3-Way Partial Least Squares for Binary Response

Axioms
In various research domains, researchers frequently encounter multiple datasets pertaining to the same subjects, with one dataset providing explanatory variables for the others.
Elisa Frutos-Bernal, Laura Vicente-González, Ana Elizabeth Sipols   +2 more
doaj   +1 more source

Color Visual Secret Sharing for QR Code with Perfect Module Reconstruction

Applied Sciences, 2019
Visual secret sharing is a secret sharing scheme where the decryption requires no computation. It has found many applications in online transaction security, privacy protection, and bar code security, etc.
Tao Liu, Bin Yan, Jeng-Shyang Pan
doaj   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

A comparison of different criteria for selecting binary tests in diagnostic keys [PDF]

, 1975
The problem of selecting tests to be used in nonprobabilistic binary diagnostic keys is discussed. Five selection criteria are compared and it is shown that all except a new criterion suffer from some deficiency.
Gower, J. C., Payne, R. W.
core   +1 more source

Continuous and binary sets of responses differ in the field

Scientific Reports, 2022
This paper conducts a pre-registered study aimed to compare binary and continuous set of responses in survey questionnaires. Binary responses consist of two possible opposing response options (Yes/No).
Noelia Rivera-Garrido, M. P. Ramos-Sosa, Michela Accerenzi, Pablo Brañas-Garza   +3 more
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

A Trust-Enhancing Variant of the Binary Randomized Response Technique

Axioms
Building on recent studies on trust enhancement in quantitative Randomized Response Technique (RRT) models, this study introduces trust enhancement in a binary mixture RRT model.
Sat Gupta, Nikita Jayaraj, Mala Gupta, Pidugu Trisandhya   +3 more
doaj   +1 more source