Results 41 to 50 of about 430,651 (258)

Color Visual Secret Sharing for QR Code with Perfect Module Reconstruction

Applied Sciences, 2019
Visual secret sharing is a secret sharing scheme where the decryption requires no computation. It has found many applications in online transaction security, privacy protection, and bar code security, etc.
Tao Liu, Bin Yan, Jeng-Shyang Pan
doaj   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

Molecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi, Stavros Makrodimitris, Sandra van Wilpe, Iris te Paske, Vanja de Weerd, Corine M. Beaufort, Hans M. Westgeest, Jens Voortman, Maureen J. B. Aarts, Maud Rijnders, Astrid A. M. van der Veldt, Ronald de Wit, Niven Mehra, Saskia M. Wilting, Debbie G. J. Robbrecht   +14 more
wiley   +1 more source

Generalized Additive Mixed-Models for Pharmacology Using Integrated Discrete Multiple Organ Co-Culture. [PDF]

PLoS ONE, 2016
Integrated Discrete Multiple Organ Co-culture (IDMOC) is emerging as an in-vitro alternative to in-vivo animal models for pharmacology studies. IDMOC allows dose-response relationships to be investigated at the tissue and organoid levels, yet, these ...
Thomas Ingersoll, Stephanie Cole, Janna Madren-Whalley, Lamont Booker, Russell Dorsey, Albert Li, Harry Salem   +6 more
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

A Trust-Enhancing Variant of the Binary Randomized Response Technique

Axioms
Building on recent studies on trust enhancement in quantitative Randomized Response Technique (RRT) models, this study introduces trust enhancement in a binary mixture RRT model.
Sat Gupta, Nikita Jayaraj, Mala Gupta, Pidugu Trisandhya   +3 more
doaj   +1 more source

An Information Theoretical Method for Analyzing Unreplicated Designs with Binary Response

Revstat Statistical Journal, 2019
The analysis of unreplicated factorial designs constitutes a challenging but difficult issue since there are no degrees of freedom so as to estimate the error variance.
Krystallenia Drosou , Christos Koukouvinos   +1 more
doaj   +1 more source

Predictors of response to pharmacotherapy in children and adolescents with psychiatric disorders: A combined post hoc analysis of four clinical trial data

Neuropsychopharmacology Reports, 2022
Objective The prediction of response to pharmacotherapy has not been sufficiently explored in children and adolescents with psychiatric disorders, which was addressed in this study.
Takashi Tsujii, Hitoshi Sakurai, Hiroyoshi Takeuchi, Takefumi Suzuki, Masaru Mimura, Hiroyuki Uchida   +5 more
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Continuous and binary sets of responses differ in the field

Scientific Reports, 2022
This paper conducts a pre-registered study aimed to compare binary and continuous set of responses in survey questionnaires. Binary responses consist of two possible opposing response options (Yes/No).
Noelia Rivera-Garrido, M. P. Ramos-Sosa, Michela Accerenzi, Pablo Brañas-Garza   +3 more
doaj   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source