Results 41 to 50 of about 941,611 (292)
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Molecular Oncology, EarlyView.Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser +14 more
wiley +1 more source
Química Nova, 2009 The high cost of sensitivity commercial calorimeters may represent an obstacle for many calorimetric research groups. This work describes the construction and calibration of a batch differential heat conduction calorimeter with sample cells volumes of ...
Rafael Bergamo Trinca +2 more
doaj +1 more source
Reconstruction of Binary Functions and Shapes from Incomplete Frequency Information
, 2012 The characterization of a binary function by partial frequency information is considered. We show that it is possible to reconstruct binary signals from incomplete frequency measurements via the solution of a simple linear optimization problem.
Mao, Yu
core +1 more source
An approximate binary-black-hole metric [PDF]
, 2000 An approximate solution to Einstein's equations representing two widely-separated non-rotating black holes in a circular orbit is constructed by matching a post-Newtonian metric to two perturbed Schwarzschild metrics. The spacetime metric is presented in
C. M. Will +13 more
core +2 more sources
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Parametric derivation of the observable relativistic periastron advance for binary pulsars
, 2005 We compute the dimensionless relativistic periastron advance parameter $k$, which is measurable from the timing of relativistic binary pulsars. We employ for the computation the recently derived Keplerian-type parametric solution to the post-Newtonian ...
Achamveedu Gopakumar +6 more
core +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Energy Reports, 2020 Operation schedule for microgrids has an important role to manage the electric power supply and demand efficiently. This paper presents a problem formulation and its solution method to obtain a coordinated operation schedule of controllable components in
Hirotaka Takano +3 more
doaj +1 more source