Results 111 to 120 of about 1,189,468 (290)

Impact of APOE ε4 Genotype Load on Cognitive Function and Lipid Metabolism in Patients With Cerebral Small Vessel Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Apolipoprotein ε4 (APOE ε4) is a potent genetic risk factor for Alzheimer's disease (AD). However, its role in cerebral small vessel disease (CSVD) remains unclear. Given the clinical and pathological similarities between CSVD and AD, this study aimed to investigate the associations of APOE ε4 gene dosage with cognitive function and
Tingru Jin, Haocheng Yang, Feng Liu, Sihao Lin, Junru Hu, Jian Wang, Yulan Gou   +6 more
wiley   +1 more source

Mining Double-line Spectroscopic Candidates in the LAMOST Medium-resolution Spectroscopic Survey Using a Human–AI Hybrid Method

The Astrophysical Journal Supplement Series
We utilize a hybrid approach that integrates the traditional cross-correlation function (CCF) and machine learning to detect spectroscopic multiple star systems, specifically focusing on double-line spectroscopic binaries (SB2s).
Shan-shan Li, Chun-qian Li, Chang-hua Li, Dong-wei Fan, Yun-fei Xu, Lin-ying Mi, Chen-zhou Cui, Jian-rong Shi   +7 more
doaj   +1 more source

Lessons Learned: Quality Analysis of Optical Coherence Tomography in Neuromyelitis Optica

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Optical coherence tomography (OCT)‐derived retina measurements are markers for neuroaxonal visual pathway status. High‐quality OCT scans are essential for reliable measurements, but their acquisition is particularly challenging in eyes with severe visual impairment, as often observed in neuromyelitis optica spectrum disorders ...
Hadi Salih, Sara Samadzadeh, Charlotte Bereuter, Seyedamirhosein Motamedi, Claudia Chien, Pablo Villoslada, Hadas Stiebel‐Kalish, Nasrin Asgari, Yang Mao‐Draayer, Marius Ringelstein, Joachim Havla, Marco Aurélio Lana Peixoto, Ho Jin Kim, Jacqueline Palace, Maria Isabel Leite, Srilakshmi M. Sharma, Fereshteh Ashtari, Rahele Kafieh, Lekha Pandit, Orhan Aktas, Philipp Albrecht, Letizia Leocani, Itay Lotan, Sasitorn Siritho, Jérôme de Seze, Romain Marignier, Caroline Froment Tilikete, Denis Bernardi Bichuetti, Ivan Maynart Tavares, Ayse Altintas, Anu Jacob, Saif Huda, Ibis Soto de Castillo, Lawrence J. Cook, Michael R. Yeaman, Axel Petzold, Alexander U. Brandt, Friedemann Paul, Frederike C. Oertel, Hanna G. Zimmermann, with the Guthy Jackson Charitable Foundation—International Clinical Consortium and CROCTINO Collaborators   +40 more
wiley   +1 more source

The TESS Ten Thousand Catalog: 10,001 Uniformly Vetted and Validated Eclipsing Binary Stars Detected in Full-frame Image Data by Machine Learning and Analyzed by Citizen Scientists

The Astrophysical Journal Supplement Series
The Transiting Exoplanet Survey Satellite (TESS) has surveyed nearly the entire sky in full-frame image mode with a time resolution of 200 s to 30 minutes and a temporal baseline of at least 27 days.
Veselin B. Kostov, Brian P. Powell, Aline U. Fornear, Marco Z. Di Fraia, Robert Gagliano, Thomas L. Jacobs, Julien S. de Lambilly, Hugo A. Durantini Luca, Steven R. Majewski, Mark Omohundro, Jerome Orosz, Saul A. Rappaport, Ryan Salik, Donald Short, William Welsh, Svetoslav Alexandrov, Cledison Marcos da Silva, Erika Dunning, Gerd Gühne, Marc Huten, Michiharu Hyogo, Davide Iannone, Sam Lee, Christian Magliano, Manya Sharma, Allan Tarr, John Yablonsky, Sovan Acharya, Fred Adams, Thomas Barclay, Benjamin T. Montet, Susan Mullally, Greg Olmschenk, Andrej Prša, Elisa Quintana, Robert Wilson, Hasret Balcioglu, Ethan Kruse, The Eclipsing Binary Patrol Collaboration   +38 more
doaj   +1 more source

Deep Learning–Assisted Differentiation of Four Peripheral Neuropathies Using Corneal Confocal Microscopy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Peripheral neuropathies contribute to patient disability but may be diagnosed late or missed altogether due to late referral, limitation of current diagnostic methods and lack of specialized testing facilities. To address this clinical gap, we developed NeuropathAI, an interpretable deep learning–based multiclass classification ...
Chaima Ben Rabah, Ioannis N. Petropoulos, Mark Stettner, Maryam Ferdousi, Uazman Alam, Nathan Efron, Ahmed Serag, Rayaz A. Malik   +7 more
wiley   +1 more source

Half a Million Binary Stars Identified from the Low-resolution Spectra of LAMOST

The Astrophysical Journal Supplement Series
Binary stars are prevalent yet challenging to detect. We present a novel approach using convolutional neural networks (CNNs) to identify binary stars from low-resolution spectra obtained by the LAMOST survey.
Yingjie Jing, Tian-Xiang Mao, Jie Wang, Chao Liu, Xiaodian Chen   +4 more
doaj   +1 more source

The role of binaries in the enrichment of the early Galactic halo. II. Carbon-Enhanced Metal-Poor Stars - CEMP-no stars

, 2015
The detailed composition of most metal-poor halo stars has been found to be very uniform. However, a fraction of 20-70% (increasing with decreasing metallicity) exhibit dramatic enhancements in their abundances of carbon - the so-called carbon-enhanced ...
Andersen, J., Beers, T. C., Buchhave, L. A., Hansen, T. T., Nordström, B., Placco, V. M., Yoon, J.   +6 more
core   +2 more sources

Prediction of Myasthenia Gravis Worsening: A Machine Learning Algorithm Using Wearables and Patient‐Reported Measures

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is a rare disorder characterized by fluctuating muscle weakness with potential life‐threatening crises. Timely interventions may be delayed by limited access to care and fragmented documentation. Our objective was to develop predictive algorithms for MG deterioration using multimodal telemedicine data ...
Maike Stein, Haoqi Sun, Sophie Lehnerer, Lea Gerischer, Maximilian Mönch, Christian Meisel, Andreas Meisel, Pushpa Narayanaswami   +7 more
wiley   +1 more source

Tracing the Origins of Mass Segregation in M35: Evidence for Primordially Segregated Binaries

The Astrophysical Journal Letters
M35 is a young open cluster and home to an extensive binary population. Using Gaia Data Release 3, Pan-STARRS, and Two Micron All Sky Survey photometry with the Bayesian statistical software, BASE-9, we derive precise cluster parameters, identify single ...
Erin Motherway, Aaron M. Geller, Anna C. Childs, Claire Zwicker, Ted von Hippel   +4 more
doaj   +1 more source

Longitudinal Relationship Between Pain and Depression in People With Inflammatory Arthritis: A Narrative Review

Arthritis Care &Research, EarlyView.
As many patients with inflammatory arthritis (IA) have chronic pain, understanding how to best assess and manage pain in IA is a priority. Comorbid depression is prevalent in adults with IA, affecting 15% to 39% of people. Although pain and depression are thought to be associated in IA, this concept is largely based on cross‐sectional data.
Natasha Cox, Saeed Farooq, Helen Twohig, Ian C. Scott   +3 more
wiley   +1 more source