Results 51 to 60 of about 1,653,589 (294)

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

TIME-DEPENDENT DISK ACCRETION IN BINARY SYSTEMS

open access: yesOdessa Astronomical Publications, 2017
The analytic investigation of time dependent accretion in disk is carried out. We consider a disk in a binary system at outburst which has fixed tidally truncated outer radius. The standard model (Shakura-Sunyaev 1973) of the disk is considered.
G. V. Lipunova, N. I. Shakura
doaj   +1 more source

Evolution of Close Binary Systems [PDF]

open access: yesThe Astrophysical Journal, 2005
We collected data on the masses, radii, etc. of three classes of close binary stars: low-temperature contact binaries (LTCBs), near-contact binaries (NCBs), and detached close binaries (DCBs). They restrict themselves to systems where (1) both components are, at least arguably, near the Main Sequence, (2) the periods are less than a day, and (3) there ...
Yakut, K, Eggleton, P
openaire   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Disk Evolution in Young Binaries: from Observations to Theory [PDF]

open access: yes, 2006
The formation of a binary system surrounded by disks is the most common outcome of stellar formation. Hence studying and understanding the formation and the evolution of binary systems and associated disks is a cornerstone of star formation science ...
Clarke, C. J.   +3 more
core   +1 more source

Evolution of binary stars and the effect of tides on binary populations [PDF]

open access: yes, 2002
We present a rapid binary evolution algorithm that enables modelling of even the most complex binary systems. In addition to all aspects of single star evolution, features such as mass transfer, mass accretion, common-envelope evolution, collisions ...
Hurley, Jarrod R.   +2 more
core   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Binary fields on limited systems [PDF]

open access: yesActa Scientiarum Mathematicarum, 2014
The intrinsic structure of binary fields poses a challenging complexity problem from both hardware and software point of view. Motivated by applications to modern cryptography, we describe some simple techniques aimed at performing computations over binary fields using systems with limited resources.
Nagy, Gábor Péter, Lanzone, v.
openaire   +3 more sources

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Triple systems and binary operations

open access: yesDiscrete Mathematics, 2014
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Ales Drápal   +2 more
openaire   +1 more source

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